Protein kinase C isoforms zeta and iota mediate collagenase expression and cartilage destruction via STAT3- and ERK-dependent c-fos induction (Q33991241)

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English	Protein kinase C isoforms zeta and iota mediate collagenase expression and cartilage destruction via STAT3- and ERK-dependent c-fos induction	scientific article

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2 February 2020

Protein kinase C isoforms zeta and iota mediate collagenase expression and cartilage destruction via STAT3- and ERK-dependent c-fos induction (English)

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2 February 2020

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Martina S Elias

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2 February 2020

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Gary J Litherland

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2 February 2020

Wang Hui

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Christopher D Macdonald

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Jonathon B Catterall

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Matt J Barter

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Matthew J Farren

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Matthew Jefferson

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Andrew D Rowan

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12 May 2010

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2 February 2020

Journal of Biological Chemistry

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285

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2 February 2020

22414-22425

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2 February 2020

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Structural basis of protein kinase C isoform function

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Protein kinase C iota: human oncogene, prognostic marker and therapeutic target

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5 July 2018

Basic fibroblast growth factor stimulates matrix metalloproteinase-13 via the molecular cross-talk between the mitogen-activated protein kinases and protein kinase Cdelta pathways in human adult articular chondrocytes

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5 July 2018

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Identification of a classic cytokine-induced enhancer upstream in the human iNOS promoter

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5 July 2018

PKCzeta at the crossroad of NF-kappaB and Jak1/Stat6 signaling pathways

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5 July 2018

Matrix metalloproteinases: role in arthritis

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5 July 2018

Atypical protein kinase Ciota plays a critical role in human lung cancer cell growth and tumorigenicity

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5 July 2018

Control of T helper 2 cell function and allergic airway inflammation by PKCzeta

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5 July 2018

Human nasal cartilage responds to oncostatin M in combination with interleukin 1 or tumour necrosis factor alpha by the release of collagen fragments via collagenases

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5 July 2018

The role of Raf kinase inhibitor protein (RKIP) in health and disease

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5 July 2018

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5 July 2018

Cellular protein kinase C isozyme regulation by exogenously delivered physiological disulfides--implications of oxidative protein kinase C regulation to cancer prevention

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Protein kinase C switches the Raf kinase inhibitor from Raf-1 to GRK-2

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5 July 2018

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1 reference

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Synergistic induction of matrix metalloproteinase 1 by interleukin-1alpha and oncostatin M in human chondrocytes involves signal transducer and activator of transcription and activator protein 1 transcription factors via a novel mechanism

1 reference

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5 July 2018

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1 reference

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21 January 2018

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21 January 2018

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1 reference

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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1 reference

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21 January 2018

Retinoic acid and oncostatin M combine to promote cartilage degradation via matrix metalloproteinase-13 expression in bovine but not human chondrocytes

1 reference

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21 January 2018

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1 reference

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21 January 2018

Oncostatin M Stimulates c-Fos to Bind a Transcriptionally Responsive AP-1 Element within the Tissue Inhibitor of Metalloproteinase-1 Promoter

1 reference

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21 January 2018

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21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/20463008

12 December 2020

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Involvement of protein kinase Czeta in interleukin-1beta induction of ADAMTS-4 and type 2 nitric oxide synthase via NF-kappaB signaling in primary human osteoarthritic chondrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20463008

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mitogen-activated protein kinase and JAK-STAT signaling pathways are required for an oncostatin M-responsive element-mediated activation of matrix metalloproteinase 1 gene expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/20463008

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of oncostatin M in animal and human connective tissue collagen turnover and its localization within the rheumatoid joint

1 reference

https://pubmed.ncbi.nlm.nih.gov/20463008

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase Czeta is up-regulated in osteoarthritic cartilage and is required for activation of NF-kappaB by tumor necrosis factor and interleukin-1 in articular chondrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20463008

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

96-Well plate assays for measuring collagenase activity using (3)H-acetylated collagen

1 reference

https://pubmed.ncbi.nlm.nih.gov/20463008

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-1 induction of collagenase 3 (matrix metalloproteinase 13) gene expression in chondrocytes requires p38, c-Jun N-terminal kinase, and nuclear factor kappaB: differential regulation of collagenase 1 and collagenase 3

1 reference

https://pubmed.ncbi.nlm.nih.gov/20463008

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retinoic acid combines with interleukin-1 to promote the degradation of collagen from bovine nasal cartilage: matrix metalloproteinases-1 and -13 are involved in cartilage collagen breakdown

1 reference

https://pubmed.ncbi.nlm.nih.gov/20463008

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The breakdown of collagen by chondrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20463008

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calphostin C (UCN-1028C), a novel microbial compound, is a highly potent and specific inhibitor of protein kinase C

1 reference

https://pubmed.ncbi.nlm.nih.gov/20463008

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Monoclonal antibodies against human fibroblast collagenase and the design of an enzyme-linked immunosorbent assay to measure total collagenase

1 reference

https://pubmed.ncbi.nlm.nih.gov/20463008

12 December 2020

based on heuristic

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Atypical protein kinase C-zeta modulates clonogenicity, motility, and secretion of proteolytic enzymes in murine mammary cells

1 reference

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based on heuristic

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Identifiers

10.1074/JBC.M110.120121

1 reference

Europe PubMed Central

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2 February 2020

PMC publication ID

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Europe PubMed Central

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2 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

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2 February 2020

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