BRAF inhibition increases tumor infiltration by T cells and enhances the antitumor activity of adoptive immunotherapy in mice (Q33996674)

30 July 2017

title

BRAF inhibition increases tumor infiltration by T cells and enhances the antitumor activity of adoptive immunotherapy in mice (English)

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30 July 2017

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15

Keith T Flaherty

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30 July 2017

21

Patrick Hwu

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30 July 2017

6

Jennifer A Wargo

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30 July 2017

11

Dennie Tompers Frederick

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30 July 2017

Chengwen Liu

1

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30 July 2017

Weiyi Peng

2

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30 July 2017

Chunyu Xu

3

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30 July 2017

Yanyan Lou

4

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30 July 2017

Minying Zhang

5

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30 July 2017

Jie Qing Chen

7

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30 July 2017

Haiyan S Li

8

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30 July 2017

Stephanie S Watowich

9

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30 July 2017

Yan Yang

10

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30 July 2017

Zachary A Cooper

12

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30 July 2017

Rina M Mbofung

13

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30 July 2017

Mayra Whittington

14

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30 July 2017

Scott E Woodman

16

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30 July 2017

Michael A Davies

17

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30 July 2017

Laszlo G Radvanyi

18

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30 July 2017

Willem W Overwijk

19

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30 July 2017

Gregory Lizée

20

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30 July 2017

language of work or name

English

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publication date

30 November 2012

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30 July 2017

published in

Clinical Cancer Research

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30 July 2017

volume

19

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30 July 2017

issue

2

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30 July 2017

page(s)

393-403

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The activation of MAPK in melanoma cells resistant to BRAF inhibition promotes PD-L1 expression that is reversible by MEK and PI3K inhibition

30 July 2017

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Acquired resistance to BRAF inhibitors mediated by a RAF kinase switch in melanoma can be overcome by cotargeting MEK and IGF-1R/PI3K

5 July 2018

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Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation

5 July 2018

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COT drives resistance to RAF inhibition through MAP kinase pathway reactivation

5 July 2018

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MEK-independent survival of B-RAFV600E melanoma cells selected for resistance to apoptosis induced by the RAF inhibitor PLX4720.

5 July 2018

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Transduction of tumor-specific T cells with CXCR2 chemokine receptor improves migration to tumor and antitumor immune responses

5 July 2018

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BMP2-activated Erk/MAP kinase stabilizes Runx2 by increasing p300 levels and histone acetyltransferase activity

5 July 2018

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Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma

5 July 2018

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Inhibition of Mutated, Activated BRAF in Metastatic Melanoma

5 July 2018

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Analysis of the genome to personalize therapy for melanoma

5 July 2018

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Antiangiogenic agents can increase lymphocyte infiltration into tumor and enhance the effectiveness of adoptive immunotherapy of cancer

5 July 2018

1 reference

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Selective BRAFV600E inhibition enhances T-cell recognition of melanoma without affecting lymphocyte function

5 July 2018

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Recovery of phospho-ERK activity allows melanoma cells to escape from BRAF inhibitor therapy.

5 July 2018

1 reference

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RAF inhibitors transactivate RAF dimers and ERK signalling in cells with wild-type BRAF

5 July 2018

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PLX4032, a selective BRAF(V600E) kinase inhibitor, activates the ERK pathway and enhances cell migration and proliferation of BRAF melanoma cells

5 July 2018

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RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth

5 July 2018

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Secretion of vascular endothelial growth factor by oral squamous cell carcinoma cells skews endothelial cells to suppress T-cell functions

5 July 2018

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Adoptive cell therapy for the treatment of patients with metastatic melanoma

5 July 2018

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MEK/ERK inhibitor U0126 affects in vitro and in vivo growth of embryonal rhabdomyosarcoma.

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Gene transfer of tumor-reactive TCR confers both high avidity and tumor reactivity to nonreactive peripheral blood mononuclear cells and tumor-infiltrating lymphocytes

5 July 2018

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Role of the mitogen-activated protein kinase signaling pathway in the regulation of human melanocytic antigen expression

5 July 2018

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The BRAF-MAPK signaling pathway is essential for cancer-immune evasion in human melanoma cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4120472

Anti-angiogenesis therapy can overcome endothelial cell anergy and promote leukocyte-endothelium interactions and infiltration in tumors.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4120472

Dendritic cells strongly boost the antitumor activity of adoptively transferred T cells in vivo.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4120472

Cancer immunotherapy: a treatment for the masses

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4120472

Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4120472

Tumor regression and autoimmunity after reversal of a functionally tolerant state of self-reactive CD8+ T cells.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4120472

Mutations of the BRAF gene in human cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4120472

VEGF as a mediator of tumor-associated immunodeficiency

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4120472

Antigen capture, processing, and presentation by dendritic cells: recent cell biological studies.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4120472

Selective BRAF inhibitors induce marked T-cell infiltration into human metastatic melanoma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4120472

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4120472

Localization of 111indium-labeled tumor infiltrating lymphocytes to tumor in patients receiving adoptive immunotherapy. Augmentation with cyclophosphamide and correlation with response

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23204132

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Vascular normalization in Rgs5-deficient tumours promotes immune destruction

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23204132

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1158/1078-0432.CCR-12-1626

1 reference

release_p7uorwe3tvczfknspv2jroasme

30 July 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/p7uorwe3tvczfknspv2jroasme

mapped directly with Wikidata item

24 November 2022

based on heuristic

PMC publication ID

4120472

1 reference

30 July 2017

1 reference