Rotational-echo double-resonance NMR distance measurements for the tubulin-bound Paclitaxel conformation (Q34001846)

30 July 2017

title

Rotational-echo double-resonance NMR distance measurements for the tubulin-bound Paclitaxel conformation (English)

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30 July 2017

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12

Lynette Cegelski

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30 July 2017

Susan Bane

5

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David G.I. Kingston

14

object named as

David G I Kingston

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30 July 2017

10

Jacob Schaefer

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30 July 2017

Younkee Paik

1

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30 July 2017

Chao Yang

2

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30 July 2017

Belhu Metaferia

3

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30 July 2017

Shoubin Tang

4

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30 July 2017

Rudravajhala Ravindra

6

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30 July 2017

Natasha Shanker

7

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30 July 2017

Ana A Alcaraz

8

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30 July 2017

Scott A Johnson

9

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30 July 2017

Robert D O'Connor

11

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30 July 2017

James P Snyder

13

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30 July 2017

language of work or name

English

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publication date

1 January 2007

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Journal of the American Chemical Society

30 July 2017

published in

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30 July 2017

volume

129

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30 July 2017

issue

2

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30 July 2017

page(s)

361-370

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Recent advances in the new generation taxane anticancer agents.

30 July 2017

cites work

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Paclitaxel-resistant cells have a mutation in the paclitaxel-binding region of beta-tubulin (Asp26Glu) and less stable microtubules

5 July 2018

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Use of the tubulin bound paclitaxel conformation for structure-based rational drug design

5 July 2018

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Recent progress in structure activity relationship and mechanistic studies of taxol analogues

5 July 2018

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The taxol pharmacophore and the T-taxol bridging principle.

5 July 2018

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Synthesis of C2-C3'N-linked macrocyclic taxoids. Novel docetaxel analogues with high tubulin activity

5 July 2018

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The bioactive Taxol conformation on beta-tubulin: experimental evidence from highly active constrained analogs.

5 July 2018

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Docetaxel and paclitaxel in the treatment of breast cancer: a review of clinical experience

5 July 2018

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Microtubules as a target for anticancer drugs

5 July 2018

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Synthesis of novel C2-C3'N-linked macrocyclic taxoids by means of highly regioselective Heck macrocyclization

5 July 2018

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Paclitaxel in cancer therapy

5 July 2018

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Design, synthesis and biological activity of novel C2-C3' N-Linked macrocyclic taxoids

5 July 2018

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Refined structure of alpha beta-tubulin at 3.5 A resolution

5 July 2018

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The binding conformation of Taxol in beta-tubulin: a model based on electron crystallographic density

5 July 2018

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SIMPSON: a general simulation program for solid-state NMR spectroscopy

5 July 2018

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5 July 2018

The taxanes: an update

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A common pharmacophore for epothilone and taxanes: molecular basis for drug resistance conferred by tubulin mutations in human cancer cells

5 July 2018

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Conformation of microtubule-bound paclitaxel determined by fluorescence spectroscopy and REDOR NMR.

5 July 2018

1 reference

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Molecular effects of paclitaxel: myths and reality (a critical review).

5 July 2018

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A common pharmacophore for cytotoxic natural products that stabilize microtubules

5 July 2018

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High-resolution model of the microtubule

5 July 2018

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Synthesis and biological evaluation of 2-acyl analogues of paclitaxel (Taxol).

5 July 2018

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Structure of the alpha beta tubulin dimer by electron crystallography

5 July 2018

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Conformation of a water-soluble derivative of taxol in water by 2D-NMR spectroscopy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2432525

THE DEVELOPMENT AND CLINICAL UTILITY OF THE TAXANE CLASS OF ANTIMICROTUBULE CHEMOTHERAPY AGENTS

5 July 2018

1 reference

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Mechanism of mitotic block and inhibition of cell proliferation by taxol at low concentrations

5 July 2018

1 reference

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Crystal and molecular structure of paclitaxel (taxol).

5 July 2018

1 reference

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Mechanism of action of taxol

5 July 2018

1 reference

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Promotion of microtubule assembly in vitro by taxol

5 July 2018

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Synthesis of novel macrocyclic docetaxel analogues. Influence of their macrocyclic ring size on tubulin activity

5 July 2018

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Synthesis and NMR-driven conformational analysis of taxol analogues conformationally constrained on the C13 side chain

29 October 2018

1 reference

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Raf-1/bcl-2 phosphorylation: a step from microtubule damage to cell death.

29 October 2018

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29 October 2018

The T-Taxol Conformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2432525

The INPHARMA Method: Protein-Mediated Interligand NOEs for Pharmacophore Mapping

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2432525

T-Taxol and the electron crystallographic density in beta-tubulin

29 October 2018

1 reference

12 December 2020

Conformationally restricted paclitaxel analogues: macrocyclic mimics of the "hydrophobic collapse" conformation

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12 December 2020

A Common Pharmacophore for Taxol and the Epothilones Based on the Biological Activity of a Taxane Molecule Lacking a C-13 Side Chain†

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12 December 2020

Microtubule structure at 8 A resolution

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12 December 2020

Identifiers

DOI

10.1021/JA0656604

1 reference

release_uf25qbfmfvcuzgr2eupzopikiu

30 July 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/uf25qbfmfvcuzgr2eupzopikiu

24 November 2022

mapped directly with Wikidata item

PMC publication ID

2432525

1 reference

30 July 2017

1 reference