Interleukin-21: a new mediator of inflammation in systemic lupus erythematosus (Q34002864)

30 July 2017

6 references

12 March 2019

13 March 2019

17 June 2019

30 June 2019

20 November 2019

8 April 2021

Interleukin-21: a new mediator of inflammation in systemic lupus erythematosus (English)

1 reference

systemic lupus erythematosus

30 July 2017

0 references

5 references

12 March 2019

13 March 2019

17 June 2019

30 June 2019

20 November 2019

1 reference

20 November 2019

inflammation mediators

1 reference

8 April 2021

Massimiliano Sarra

1

1 reference

PubMed ID

20652041

30 July 2017

Giovanni Monteleone

series ordinal

2

1 reference

30 July 2017

28 June 2010

7 references

Journal of Biomedicine and Biotechnology

30 July 2017

12 March 2019

13 March 2019

17 June 2019

30 June 2019

20 November 2019

8 April 2021

7 references

30 July 2017

12 March 2019

13 March 2019

17 June 2019

30 June 2019

20 November 2019

8 April 2021

2010

1 reference

30 July 2017

294582

1 reference

Creative Commons Attribution 3.0 Unported

30 July 2017

start time

1 January 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

cites work

B cell-intrinsic signaling through IL-21 receptor and STAT3 is required for establishing long-lived antibody responses in humans

1 reference

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Elevated interleukin-21 correlated to Th17 and Th1 cells in patients with immune thrombocytopenia

5 July 2018

1 reference

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A novel subpopulation of B-1 cells is enriched with autoreactivity in normal and lupus-prone mice.

5 July 2018

1 reference

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IL-21 and T follicular helper cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905909

A polymorphism within IL21R confers risk for systemic lupus erythematosus

5 July 2018

1 reference

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Interleukin-21 as a new therapeutic target for immune-mediated diseases

5 July 2018

1 reference

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T-cell and B-cell signaling biomarkers and treatment targets in lupus

5 July 2018

1 reference

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A vital role for interleukin-21 in the control of a chronic viral infection

5 July 2018

1 reference

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IL-21 is required to control chronic viral infection

5 July 2018

1 reference

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Follicular helper T cells: lineage and location

5 July 2018

1 reference

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Testing for the association of the KIAA1109/Tenr/IL2/IL21 gene region with rheumatoid arthritis in a European family-based study

5 July 2018

1 reference

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IL-21 mediates suppressive effects via its induction of IL-10.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905909

Follicular helper T cells are required for systemic autoimmunity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905909

IL-21: an executor of B cell fate

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905909

Genetic variants in the region harbouring IL2/IL21 associated with ulcerative colitis

5 July 2018

1 reference

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A critical role for IL-21 receptor signaling in the pathogenesis of systemic lupus erythematosus in BXSB-Yaa mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905909

ICOS-dependent extrafollicular helper T cells elicit IgG production via IL-21 in systemic autoimmunity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905909

Involvement of ERK-1/2 in IL-21-induced cytokine production in leukemia cells and human monocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905909

Anomalous type 17 response to viral infection by CD8+ T cells lacking T-bet and eomesodermin.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905909

The role of IL-21 in regulating B-cell function in health and disease.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905909

A fundamental role for interleukin-21 in the generation of T follicular helper cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905909

The Yin and Yang of interleukin-21 in allergy, autoimmunity and cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905909

IL-21 and TGF-beta are required for differentiation of human T(H)17 cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905909

Interleukin 21: a cytokine/cytokine receptor system that has come of age

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905909

Interleukin-21: a critical regulator of the balance between effector and regulatory T-cell responses

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905909

A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905909

Interleukin-21: Basic Biology and Implications for Cancer and Autoimmunity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905909

IL-21 synergizes with IL-7 to augment expansion and anti-tumor function of cytotoxic T cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905909

IL-21 initiates an alternative pathway to induce proinflammatory T(H)17 cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905909

IL-6 programs T(H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905909

A genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905909

Molecular scanning of interleukin-21 gene and genetic susceptibility to type 1 diabetes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905909

IL-21 has a pathogenic role in a lupus-prone mouse model and its blockade with IL-21R.Fc reduces disease progression.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905909

IL-21 is produced by NKT cells and modulates NKT cell activation and cytokine production

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905909

IL-21 receptor signaling is integral to the development of Th2 effector responses in vivo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905909

The IL-21 receptor augments Th2 effector function and alternative macrophage activation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905909

B cells as antigen presenting cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905909

T- and B-cell abnormalities in systemic lupus erythematosus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905909

A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905909

Interleukin-21 enhances T-helper cell type I signaling and interferon-gamma production in Crohn's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905909

Synergy of IL-21 and IL-15 in regulating CD8+ T cell expansion and function.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905909

Regulation of B cell differentiation and plasma cell generation by IL-21, a novel inducer of Blimp-1 and Bcl-6

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905909

B cells in human and murine systemic lupus erythematosus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905909

Interleukin-21 inhibits dendritic cell activation and maturation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905909

A critical role for IL-21 in regulating immunoglobulin production

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905909

IL-21 up-regulates the expression of genes associated with innate immunity and Th1 response

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905909

Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905909

Lessons from BXSB and related mouse models

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905909

B cells are required for lupus nephritis in the polygenic, Fas-intact MRL model of systemic autoimmunity.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905909

A novel mouse with B cells but lacking serum antibody reveals an antibody-independent role for B cells in murine lupus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905909

Role of interleukin 10 in the B lymphocyte hyperactivity and autoantibody production of human systemic lupus erythematosus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905909

Systemic lupus erythematosus.

5 July 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F294582

Cytokine-mediated regulation of human B cell differentiation into Ig-secreting cells: predominant role of IL-21 produced by CXCR5+ T follicular helper cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F294582

Distinct activation signals determine whether IL-21 induces B cell costimulation, growth arrest, or Bim-dependent apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F294582

Regulation of gut inflammation and th17 cell response by interleukin-21.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F294582

Treatment of BXSB-Yaa mice with IL-21R-Fc fusion protein minimally attenuates systemic lupus erythematosus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F294582

IL-21R on T cells is critical for sustained functionality and control of chronic viral infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F294582

Genetic association of interleukin-21 polymorphisms with systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F294582

Decreased expression of interleukin-21 receptor on peripheral B lymphocytes in systemic lupus erythematosus.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905909

Involvement of interleukin-21 in the epidermal hyperplasia of psoriasis

29 October 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F294582

A Functional Role for Interleukin-21 in Promoting the Synthesis of the T-Cell Chemoattractant, MIP-3α, by Gut Epithelial Cells

21 January 2018

1 reference

12 December 2020

Elevated production of B cell chemokine CXCL13 is correlated with systemic lupus erythematosus disease activity

1 reference

12 December 2020

Interferon-gamma-expressing cells are a major source of interleukin-21 in inflammatory bowel diseases

1 reference

12 December 2020

IL-21 induces the apoptosis of resting and activated primary B cells

1 reference

12 December 2020

Rituximab improves peripheral B cell abnormalities in human systemic lupus erythematosus

1 reference

12 December 2020

Spontaneous production of interleukin-10 by B lymphocytes and monocytes in systemic lupus erythematosus

1 reference

12 December 2020

A Common Exonic Variant of Interleukin21 Confers Susceptibility to Atopic Asthma

1 reference

12 December 2020

Interleukin-21: biology and application to cancer therapy

1 reference

12 December 2020

Identifiers

DOI

10.1155/2010/294582

1 reference

30 July 2017

1 reference

30 July 2017

1 reference

PubMed ID

20652041