Slit2N and Robo4 regulate lymphangiogenesis through the VEGF-C/VEGFR-3 pathway (Q34003819)

30 July 2017

title

Slit2N and Robo4 regulate lymphangiogenesis through the VEGF-C/VEGFR-3 pathway (English)

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30 July 2017

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7

Jerome E Groopman

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30 July 2017

Jinlong Yu

1

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30 July 2017

Xuefeng Zhang

2

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30 July 2017

Paula M Kuzontkoski

3

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30 July 2017

Shuxian Jiang

4

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30 July 2017

Weiquan Zhu

5

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30 July 2017

Dean Y Li

6

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30 July 2017

publication date

7 April 2014

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Cell Communication and Signaling

30 July 2017

published in

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30 July 2017

volume

12

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30 July 2017

page(s)

25

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describes a project that uses

30 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4122147/fullTextXML

inferred from PubMed Central ID database lookup

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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Magic roundabout is a new member of the roundabout receptor family that is endothelial specific and expressed at sites of active angiogenesis

28 July 2018

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Stimulation of beta 1 integrin induces tyrosine phosphorylation of vascular endothelial growth factor receptor-3 and modulates cell migration

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122147

Diversity and specificity of actions of Slit2 proteolytic fragments in axon guidance

28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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Slit proteins bind Robo receptors and have an evolutionarily conserved role in repulsive axon guidance

28 July 2018

1 reference

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Vascular endothelial growth factors VEGF-B and VEGF-C are expressed in human tumors

28 July 2018

1 reference

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A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases

28 July 2018

1 reference

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The effect of the expression of vascular endothelial growth factor (VEGF)-C and VEGF receptor-3 on the clinical outcome in patients with gastric carcinoma

28 July 2018

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Vascular endothelial growth factor C (VEGF-C) in esophageal cancer correlates with lymph node metastasis and poor patient prognosis

21 January 2018

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HER2/neu expression correlates with vascular endothelial growth factor-C and lymphangiogenesis in lymph node-positive breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1478-811X-12-25

Expression of the fms-like tyrosine kinase 4 gene becomes restricted to lymphatic endothelium during development.

21 January 2018

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https://api.crossref.org/works/10.1186%2F1478-811X-12-25

Cloning and expression of three zebrafish roundabout homologs suggest roles in axon guidance and cell migration.

21 January 2018

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Biochemical purification of a mammalian slit protein as a positive regulator of sensory axon elongation and branching

21 January 2018

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https://api.crossref.org/works/10.1186%2F1478-811X-12-25

Robo4 counteracts VEGF signaling.

21 January 2018

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https://api.crossref.org/works/10.1186%2F1478-811X-12-25

Induction of tumor angiogenesis by Slit-Robo signaling and inhibition of cancer growth by blocking Robo activity

21 January 2018

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https://api.crossref.org/works/10.1186%2F1478-811X-12-25

Vascular endothelial growth factor receptor-3 directly interacts with phosphatidylinositol 3-kinase to regulate lymphangiogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1478-811X-12-25

Ligand-induced vascular endothelial growth factor receptor-3 (VEGFR-3) heterodimerization with VEGFR-2 in primary lymphatic endothelial cells regulates tyrosine phosphorylation sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1478-811X-12-25

Extracellular matrix regulates endothelial functions through interaction of VEGFR-3 and integrin alpha5beta1.

21 January 2018

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Molecular regulation of angiogenesis and lymphangiogenesis

21 January 2018

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SLIT2 attenuation during lung cancer progression deregulates beta-catenin and E-cadherin and associates with poor prognosis

21 January 2018

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https://api.crossref.org/works/10.1186%2F1478-811X-12-25

Ephrin-B2 regulates VEGFR2 function in developmental and tumour angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1478-811X-12-25

Robo4-dependent Slit signaling stabilizes the vasculature during pathologic angiogenesis and cytokine storm

21 January 2018

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https://api.crossref.org/works/10.1186%2F1478-811X-12-25

Tumor lymphangiogenesis as a potential therapeutic target

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122147

Expression of vascular endothelial growth factor (VEGF) family members in breast cancer.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4122147

Vegf, Vegf-B, Vegf-C and their receptors KDR, FLT-1 and FLT-4 during the neoplastic progression of human colonic mucosa

29 October 2018

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12 December 2020

Down-regulation of vascular endothelial cell growth factor-C expression using small interfering RNA vectors in mammary tumors inhibits tumor lymphangiogenesis and spontaneous metastasis and enhances survival

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12 December 2020

Expression of vascular endothelial growth factors A, B, C, and D and their relationships to lymph node status in lung adenocarcinoma

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Clinical significance of vascular endothelial growth factors C and D and chemokine receptor CCR7 in gastric cancer

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Slit2-N inhibits PDGF-induced migration in rat airway smooth muscle cells: WASP and Arp2/3 involved

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Expression of vascular endothelial growth factors C and D correlates with lymphangiogenesis and lymph node metastasis in lung adenocarcinoma

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12 December 2020

Role of vascular endothelial growth factor C expression in the development of lymph node metastasis in gastric cancer

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12 December 2020

Identification and characterization of roundabout orthologs in zebrafish

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Lymphangiogenesis and cancer metastasis

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Increased vascular endothelial growth factor and vascular endothelial growth factor-c and decreased nm23 expression associated with microdissemination in the lymph nodes in stage I non-small cell lung cancer

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12 December 2020

VEGFc and VEGFR3 expression in human thyroid pathologies

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12 December 2020

Vascular endothelial growth factor-C gene expression in papillary and follicular thyroid carcinomas

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12 December 2020

Signal transduction by vascular endothelial growth factor receptors

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12 December 2020

Soluble Robo4 receptor inhibits in vivo angiogenesis and endothelial cell migration

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12 December 2020

Identifiers

DOI

10.1186/1478-811X-12-25

1 reference

Dimensions Publication ID

30 July 2017

0 references

1 reference

30 July 2017

1 reference