Gene knockdowns in adult animals: PPMOs and vivo-morpholinos (Q34016744)

1 July 2019

2 references

17 September 2019

19 September 2019

Gene knockdowns in adult animals: PPMOs and vivo-morpholinos (English)

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1 July 2019

biomedical investigative technique

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17 September 2019

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19 September 2019

Jon D Moulton

1

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1 July 2019

Shan Jiang

series ordinal

2

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1 July 2019

language of work or name

English

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publication date

25 March 2009

3 references

1 July 2019

17 September 2019

19 September 2019

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1 July 2019

17 September 2019

19 September 2019

14

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1 July 2019

issue

3

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1 July 2019

page(s)

1304-1323

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1 July 2019

Creative Commons Attribution

copyright license

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17 September 2019

19 September 2019

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Morpholino, siRNA, and S-DNA compared: impact of structure and mechanism of action on off-target effects and sequence specificity

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14031304

A simple method for delivering morpholino antisense oligos into the cytoplasm of cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14031304

Hepatitis C virus internal ribosome entry site (IRES) stem loop IIId contains a phylogenetically conserved GGG triplet essential for translation and IRES folding

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14031304

Controlling morpholino experiments: don't stop making antisense.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14031304

Beta-catenin signaling activity dissected in the early Xenopus embryo: a novel antisense approach

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14031304

Systemic delivery of morpholino oligonucleotide restores dystrophin expression bodywide and improves dystrophic pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14031304

Morpholino antisense oligomers: design, preparation, and properties

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14031304

Stability of cell-penetrating peptide-morpholino oligomer conjugates in human serum and in cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14031304

Arginine-rich peptide conjugation to morpholino oligomers: effects on antisense activity and specificity.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14031304

The design, synthesis, and evaluation of molecules that enable or enhance cellular uptake: peptoid molecular transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14031304

Delivery of steric block morpholino oligomers by (R-X-R)4 peptides: structure-activity studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14031304

Design and synthesis of dendritic molecular transporter that achieves efficient in vivo delivery of morpholino antisense oligo

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14031304

HIV Tat peptide enhances cellular delivery of antisense morpholino oligomers.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14031304

Cell-penetrating peptides as transporters for morpholino oligomers: effects of amino acid composition on intracellular delivery and cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14031304

Cell-penetrating peptides. A reevaluation of the mechanism of cellular uptake

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14031304

Vectorization of morpholino oligomers by the (R-Ahx-R)4 peptide allows efficient splicing correction in the absence of endosomolytic agents.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14031304

Inhibition of coxsackievirus B3 in cell cultures and in mice by peptide-conjugated morpholino oligomers targeting the internal ribosome entry site.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14031304

Antiviral effects of antisense morpholino oligomers in murine coronavirus infection models

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14031304

Sustained dystrophin expression induced by peptide-conjugated morpholino oligomers in the muscles of mdx mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14031304

Arginine-rich cell-penetrating peptides with uncharged antisense oligomers

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14031304

Role of membrane potential and hydrogen bonding in the mechanism of translocation of guanidinium-rich peptides into cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14031304

Vivo-Morpholinos: a non-peptide transporter delivers Morpholinos into a wide array of mouse tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14031304

Inhibition of dengue virus serotypes 1 to 4 in vero cell cultures with morpholino oligomers

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14031304

Inhibition of RNA virus infections with peptide-conjugated morpholino oligomers

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14031304

Efficient stimulation of site-specific ribosome frameshifting by antisense oligonucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14031304

Exogenous control of mammalian gene expression through modulation of RNA self-cleavage

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14031304

Achieving targeted and quantifiable alteration of mRNA splicing with Morpholino oligos

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14031304

Correction of aberrant FGFR1 alternative RNA splicing through targeting of intronic regulatory elements

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14031304

Inhibition of zebrafish fgf8 pre-mRNA splicing with morpholino oligos: a quantifiable method for gene knockdown.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14031304

MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14031304

Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14031304

Zebrafish miR-214 modulates Hedgehog signaling to specify muscle cell fate

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14031304

Targeted inhibition of miRNA maturation with morpholinos reveals a role for miR-375 in pancreatic islet development

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14031304

Target protectors reveal dampening and balancing of Nodal agonist and antagonist by miR-430.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14031304

Effective rescue of dystrophin improves cardiac function in dystrophin-deficient mice by a modified morpholino oligomer

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14031304

Cell-penetrating peptide-conjugated antisense oligonucleotides restore systemic muscle and cardiac dystrophin expression and function.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14031304

RNA repair restores hemoglobin expression in IVS2-654 thalassemic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14031304

Nucleic acid-based inhibition of flavivirus infections

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14031304

Treatment of AG129 mice with antisense morpholino oligomers increases survival time following challenge with dengue 2 virus.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14031304

Inhibition of influenza A H3N8 virus infections in mice by morpholino oligomers

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14031304

Dystrophin expression in the mdx mouse after localised and systemic administration of a morpholino antisense oligonucleotide

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES14031304

Peptide-assisted delivery of steric-blocking antisense oligomers.

21 January 2018

1 reference

12 December 2020

Efficacy of systemic morpholino exon-skipping in Duchenne dystrophy dogs

1 reference

12 December 2020

Morpholino antisense oligomers: the case for an RNase H-independent structural type

1 reference

12 December 2020

Octa-guanidine morpholino restores dystrophin expression in cardiac and skeletal muscles and ameliorates pathology in dystrophic mdx mice

1 reference

12 December 2020

Endo-Porter: a novel reagent for safe, effective delivery of substances into cells

1 reference

12 December 2020

Chemical modifications of antisense morpholino oligomers enhance their efficacy against Ebola virus infection

1 reference

12 December 2020

Using Morpholinos to control gene expression.

1 reference

12 December 2020

10.3390/MOLECULES14031304

Identifiers

DOI

1 reference

1 July 2019

PMC publication ID

6253989

1 reference

1 July 2019

PubMed publication ID

19325525

1 reference

1 July 2019