Ubiquitin regulates GGA3-mediated degradation of BACE1 (Q34025306)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20484053%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

title

Ubiquitin regulates GGA3-mediated degradation of BACE1 (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20484053%20AND%20SRC:MED&resulttype=core&format=json

Golgi associated, gamma adaptin ear containing, ARF binding protein 3

2 February 2020

main subject

1 reference

GOA release 2020-03-11

ubiquitin binding

1 reference

GOA release 2020-03-11

author

Fabrizio Piazza

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20484053%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

author name string

Eugene L Kang

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20484053%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

Andrew N Cameron

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20484053%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

Kendall R Walker

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20484053%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

Giuseppina Tesco

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20484053%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

language of work or name

English

0 references

publication date

18 May 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20484053%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

2 February 2020

published in

1 reference

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2 February 2020

volume

285

1 reference

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2 February 2020

issue

31

1 reference

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2 February 2020

page(s)

24108-24119

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VHS domains of ESCRT-0 cooperate in high-avidity binding to polyubiquitinated cargo

2 February 2020

cites work

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5 July 2018

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Depletion of GGA3 stabilizes BACE and enhances beta-secretase activity

5 July 2018

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5 July 2018

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Transport of LAPTM5 to lysosomes requires association with the ubiquitin ligase Nedd4, but not LAPTM5 ubiquitination

5 July 2018

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Differential regulation of EGF receptor internalization and degradation by multiubiquitination within the kinase domain

5 July 2018

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BACE is degraded via the lysosomal pathway

5 July 2018

1 reference

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Molecular mechanism of ubiquitin recognition by GGA3 GAT domain

5 July 2018

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GGA proteins regulate retrograde transport of BACE1 from endosomes to the trans-Golgi network

5 July 2018

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Parkin mediates nonclassical, proteasomal-independent ubiquitination of synphilin-1: implications for Lewy body formation

5 July 2018

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Structural mechanism for ubiquitinated-cargo recognition by the Golgi-localized, gamma-ear-containing, ADP-ribosylation-factor-binding proteins

5 July 2018

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Optimized large-scale production of high titer lentivirus vector pseudotypes

5 July 2018

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The GAT domains of clathrin-associated GGA proteins have two ubiquitin binding motifs

5 July 2018

1 reference

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Demonstration of BACE (beta-secretase) phosphorylation and its interaction with GGA1 in cells by fluorescence-lifetime imaging microscopy

5 July 2018

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Degradation of BACE by the ubiquitin-proteasome pathway

5 July 2018

1 reference

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Reticulon family members modulate BACE1 activity and amyloid-beta peptide generation

5 July 2018

1 reference

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GGA proteins bind ubiquitin to facilitate sorting at the trans-Golgi network

5 July 2018

1 reference

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Interactions of GGA3 with the ubiquitin sorting machinery

5 July 2018

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The GGA proteins: adaptors on the move

5 July 2018

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GAT (GGA and Tom1) domain responsible for ubiquitin binding and ubiquitination.

5 July 2018

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Biochemical and structural characterization of the interaction of memapsin 2 (beta-secretase) cytosolic domain with the VHS domain of GGA proteins

5 July 2018

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Hrs regulates multivesicular body formation via ESCRT recruitment to endosomes

5 July 2018

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TSG101 interaction with HRS mediates endosomal trafficking and receptor down-regulation

5 July 2018

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5 July 2018

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STAM and Hrs are subunits of a multivalent ubiquitin-binding complex on early endosomes

5 July 2018

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5 July 2018

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5 July 2018

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Mammalian class E vps proteins recognize ubiquitin and act in the removal of endosomal protein-ubiquitin conjugates

5 July 2018

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5 July 2018

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5 July 2018

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Purification and cloning of amyloid precursor protein beta-secretase from human brain

5 July 2018

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Membrane-anchored aspartyl protease with Alzheimer's disease beta-secretase activity

5 July 2018

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Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

5 July 2018

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A function for monoubiquitination in the internalization of a G protein-coupled receptor

5 July 2018

1 reference

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The carboxyl-terminus of BACE contains a sorting signal that regulates BACE trafficking but not the formation of total A(beta).

5 July 2018

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Insights into the phosphoregulation of beta-secretase sorting signal by the VHS domain of GGA1.

21 January 2018

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Ubiquitination and proteasomal activity is required for transport of the EGF receptor to inner membranes of multivesicular bodies

21 January 2018

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GGA proteins mediate the recycling pathway of memapsin 2 (BACE).

21 January 2018

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Mutant ubiquitin-mediated beta-secretase stability via activation of caspase-3 is related to beta-amyloid accumulation in ischemic striatum in rats

21 January 2018

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Dose-dependent inhibition of proteasome activity by a mutant ubiquitin associated with neurodegenerative disease

21 January 2018

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Maturation and endosomal targeting of beta-site amyloid precursor protein-cleaving enzyme. The Alzheimer's disease beta-secretase

21 January 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/20484053

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M109.092742

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20484053%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20484053%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

PubMed publication ID

20484053

1 reference