Barbiturates require the N terminus and first transmembrane domain of the delta subunit for enhancement of alpha1beta3delta GABAA receptor currents (Q34025382)

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English	Barbiturates require the N terminus and first transmembrane domain of the delta subunit for enhancement of alpha1beta3delta GABAA receptor currents	scientific article

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scholarly article

1 reference

Europe PubMed Central

30 July 2017

Barbiturates require the N terminus and first transmembrane domain of the delta subunit for enhancement of alpha1beta3delta GABAA receptor currents (English)

1 reference

Europe PubMed Central

30 July 2017

transmembrane protein

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author name string

Hua-Jun Feng

1

1 reference

Europe PubMed Central

30 July 2017

Robert L Macdonald

2

1 reference

Europe PubMed Central

30 July 2017

language of work or name

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publication date

4 June 2010

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Europe PubMed Central

30 July 2017

Journal of Biological Chemistry

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Europe PubMed Central

30 July 2017

285

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Europe PubMed Central

30 July 2017

31

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Europe PubMed Central

30 July 2017

23614-23621

1 reference

Europe PubMed Central

30 July 2017

Extrasynaptic GABAA receptors: form, pharmacology, and function

1 reference

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5 July 2018

Tryptophan mutations at azi-etomidate photo-incorporation sites on alpha1 or beta2 subunits enhance GABAA receptor gating and reduce etomidate modulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911329

5 July 2018

Etomidate, propofol and the neurosteroid THDOC increase the GABA efficacy of recombinant alpha4beta3delta and alpha4beta3 GABA A receptors expressed in HEK cells

1 reference

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5 July 2018

Variations on an inhibitory theme: phasic and tonic activation of GABA(A) receptors

1 reference

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5 July 2018

Multiple actions of propofol on alphabetagamma and alphabetadelta GABAA receptors

1 reference

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5 July 2018

Diversity of inhibitory neurotransmission through GABA(A) receptors

1 reference

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5 July 2018

Pentobarbital differentially modulates alpha1beta3delta and alpha1beta3gamma2L GABAA receptor currents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911329

5 July 2018

Proton modulation of alpha 1 beta 3 delta GABAA receptor channel gating and desensitization

1 reference

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5 July 2018

Activation of GABA(A) receptors containing the alpha4 subunit by GABA and pentobarbital

1 reference

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5 July 2018

Neurosteroids shift partial agonist activation of GABA(A) receptor channels from low- to high-efficacy gating patterns.

1 reference

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5 July 2018

Ethanol enhances alpha 4 beta 3 delta and alpha 6 beta 3 delta gamma-aminobutyric acid type A receptors at low concentrations known to affect humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911329

5 July 2018

Neuroactive steroids reduce neuronal excitability by selectively enhancing tonic inhibition mediated by delta subunit-containing GABAA receptors

1 reference

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5 July 2018

Structure and gating mechanism of the acetylcholine receptor pore

1 reference

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5 July 2018

Coupling of agonist binding to channel gating in the GABA(A) receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911329

5 July 2018

Hormonally regulated alpha(4)beta(2)delta GABA(A) receptors are a target for alcohol

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911329

5 July 2018

Mutation of the GABAA receptor M1 transmembrane proline increases GABA affinity and reduces barbiturate enhancement.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911329

5 July 2018

Tracazolate reveals a novel type of allosteric interaction with recombinant gamma-aminobutyric acid(A) receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911329

5 July 2018

Enhanced neurosteroid potentiation of ternary GABA(A) receptors containing the delta subunit.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911329

5 July 2018

Modulation of GABA(A) receptor channel gating by pentobarbital

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911329

5 July 2018

alpha4beta3delta GABA(A) receptors characterized by fluorescence resonance energy transfer-derived measurements of membrane potential

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911329

5 July 2018

Structural determinants of fast desensitization and desensitization-deactivation coupling in GABAa receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911329

5 July 2018

Acetylcholine receptor channel structure in the resting, open, and desensitized states probed with the substituted-cysteine-accessibility method

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911329

5 July 2018

A single glycine residue at the entrance to the first membrane-spanning domain of the gamma-aminobutyric acid type A receptor beta(2) subunit affects allosteric sensitivity to GABA and anesthetics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911329

5 July 2018

Effects of halothane on GABA(A) receptor kinetics: evidence for slowed agonist unbinding.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911329

5 July 2018

Attenuated sensitivity to neuroactive steroids in gamma-aminobutyrate type A receptor delta subunit knockout mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911329

5 July 2018

The diversity of GABAA receptors. Pharmacological and electrophysiological properties of GABAA channel subtypes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911329

5 July 2018

The location of the gate in the acetylcholine receptor channel.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911329

5 July 2018

Contribution of the beta subunit M2 segment to the ion-conducting pathway of the acetylcholine receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911329

5 July 2018

Single channel properties of recombinant GABAA receptors containing gamma 2 or delta subtypes expressed with alpha 1 and beta 3 subtypes in mouse L929 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911329

5 July 2018

Expression of functional GABAA receptors in transfected L929 cells isolated by immunomagnetic bead separation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911329

5 July 2018

Which GABAA-receptor subtypes really occur in the brain?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911329

5 July 2018

Channel gating governed symmetrically by conserved leucine residues in the M2 domain of nicotinic receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911329

5 July 2018

Assembly of GABAA receptor subunits: role of the delta subunit

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911329

5 July 2018

Barbiturate enhancement of GABA-mediated inhibition and activation of chloride ion conductance: correlation with anticonvulsant and anesthetic actions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911329

5 July 2018

Modulation of recombination human gamma-aminobutyric acidA receptors by isoflurane: influence of the delta subunit.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.122564

21 January 2018

Identification of acetylcholine receptor channel-lining residues in the M1 segment of the alpha-subunit.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.122564

21 January 2018

Backbone mutations in transmembrane domains of a ligand-gated ion channel: implications for the mechanism of gating.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.122564

21 January 2018

The actions of sevoflurane and desflurane on the gamma-aminobutyric acid receptor type A: effects of TM2 mutations in the alpha and beta subunits

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.122564

21 January 2018

Identification of a GABAA receptor anesthetic binding site at subunit interfaces by photolabeling with an etomidate analog.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.122564

21 January 2018

Anaesthetic binding sites for etomidate and propofol on a GABAA receptor model.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.122564

21 January 2018

A conserved tyrosine in the beta2 subunit M4 segment is a determinant of gamma-aminobutyric acid type A receptor sensitivity to propofol.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.122564

21 January 2018

Desensitized states prolong GABAA channel responses to brief agonist pulses.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.122564

21 January 2018

Microscopic kinetic determinants of macroscopic currents: insights from coupling and uncoupling of GABAA receptor desensitization and deactivation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.122564

21 January 2018

The role of conserved leucines in the M2 domain of the acetylcholine receptor in channel gating.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911329

29 October 2018

GABAA receptor subunit gamma2 and delta subtypes confer unique kinetic properties on recombinant GABAA receptor currents in mouse fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/20525684

12 December 2020

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10.1074/JBC.M110.122564

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Europe PubMed Central

30 July 2017

release_augbcklh5vd7tg6f73wfqh2to4

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1 reference

Europe PubMed Central

30 July 2017

1 reference

Europe PubMed Central

30 July 2017

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