Urokinase receptor and integrin partnership: coordination of signaling for cell adhesion, migration and growth. (Q34026314)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10978898%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

review article

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title

Urokinase receptor and integrin partnership: coordination of signaling for cell adhesion, migration and growth (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10978898%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

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2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10978898%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

author name string

L Ossowski

series ordinal

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10978898%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

publication date

1 October 2000

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Current Opinion in Cell Biology

9 November 2019

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10978898%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

volume

12

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9 November 2019

issue

5

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9 November 2019

page(s)

613-620

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Plasminogen activators, integrins, and the coordinated regulation of cell adhesion and migration

9 November 2019

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Production of second messengers following chemotactic and mitogenic urokinase-receptor interaction in human fibroblasts and mouse fibroblasts transfected with human urokinase receptor

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Tumor dormancy induced by downregulation of urokinase receptor in human carcinoma involves integrin and MAPK signaling

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Identification of a urokinase receptor-integrin interaction site. Promiscuous regulator of integrin function

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Myosin light chain kinase functions downstream of Ras/ERK to promote migration of urokinase-type plasminogen activator-stimulated cells in an integrin-selective manner

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The urokinase plasminogen activator receptor (UPAR) is preferentially induced by nerve growth factor in PC12 pheochromocytoma cells and is required for NGF-driven differentiation.

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Urokinase receptor (CD87) regulates leukocyte recruitment via beta 2 integrins in vivo.

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Nonproteolytic role for the urokinase receptor in cellular migration in vivo.

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Intracellular transport of GPI-anchored proteins

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GM3-enriched Microdomain Involved in Cell Adhesion and Signal Transduction through Carbohydrate-Carbohydrate Interaction in Mouse Melanoma B16 Cells

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uPA, uPAR, PAI-1: key intersection of proteolytic, adhesive and chemotactic highways?

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Expression and localization of elements of the plasminogen activation system in benign breast disease and breast cancers

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Reduction in surface urokinase receptor forces malignant cells into a protracted state of dormancy

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Proteolytic cleavage of the urokinase receptor substitutes for the agonist-induced chemotactic effect

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A urokinase-sensitive region of the human urokinase receptor is responsible for its chemotactic activity.

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7 January 2021

Cleavage of urokinase receptor regulates its interaction with integrins in thyroid cells.

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Glycosylation profile of a recombinant urokinase-type plasminogen activator receptor expressed in Chinese hamster ovary cells

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7 January 2021

Mapping part of the functional epitope for ligand binding on the receptor for urokinase-type plasminogen activator by site-directed mutagenesis

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Identification of specific sites involved in ligand binding by photoaffinity labeling of the receptor for the urokinase-type plasminogen activator. Residues located at equivalent positions in uPAR domains I and III participate in the assembly [...]

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7 January 2021

Urokinase plasminogen activator induces human smooth muscle cell migration and proliferation via distinct receptor-dependent and proteolysis-dependent mechanisms

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Urokinase-type plasminogen activator stimulates the Ras/Extracellular signal-regulated kinase (ERK) signaling pathway and MCF-7 cell migration by a mechanism that requires focal adhesion kinase, Src, and Shc. Rapid dissociation of GRB2/Sps-Shc compl

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A requirement for caveolin-1 and associated kinase Fyn in integrin signaling and anchorage-dependent cell growth

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Urokinase receptor-dependent and -independent p56/59(hck) activation state is a molecular switch between myelomonocytic cell motility and adherence

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Binding of urokinase-type plasminogen activator to its receptor in MCF-7 cells activates extracellular signal-regulated kinase 1 and 2 which is required for increased cellular motility

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Urokinase induces activation and formation of Stat4 and Stat1-Stat2 complexes in human vascular smooth muscle cells

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Urokinase activates calcium-dependent potassium channels in U937 cells via calcium release from intracellular stores

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Urokinase receptor-deficient mice have impaired neutrophil recruitment in response to pulmonary Pseudomonas aeruginosa infection

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Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10978898%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

1 reference