Repair of telomeric DNA prior to replicative senescence (Q34034005)

30 July 2017

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title

Repair of telomeric DNA prior to replicative senescence (English)

1 reference

30 July 2017

Lansdorp PM

1

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30 July 2017

1 September 2000

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Mechanisms of Ageing and Development

30 July 2017

1 reference

30 July 2017

118

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30 July 2017

1-2

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30 July 2017

23-34

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Telomere length predicts replicative capacity of human fibroblasts

30 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

Atm-deficient mice: a paradigm of ataxia telangiectasia

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

Structure and function of telomeres

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

Telomere shortening and tumor formation by mouse cells lacking telomerase RNA

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

Extension of life-span by introduction of telomerase into normal human cells

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

Components of the Ku-dependent non-homologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

Sir proteins, Rif proteins, and Cdc13p bind Saccharomyces telomeres in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

Asymmetric cell divisions sustain long-term hematopoiesis from single-sorted human fetal liver cells

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

Telomere dynamics and telomerase activity in in vitro immortalised human cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

UbcD1, a Drosophila ubiquitin-conjugating enzyme required for proper telomere behavior

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

Telomere length and replicative aging in human vascular tissues

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

A human telomeric protein

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

Dissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

Functions of poly(ADP-ribose) polymerase in controlling telomere length and chromosomal stability.

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

Unlimited mileage from telomerase?

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

Replicative senescence: the human fibroblast comes of age.

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

Yeast Ku as a regulator of chromosomal DNA end structure

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

Telomere length regulation

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https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

Telomerase activity, cell proliferation, and cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

Identification of a specific telomere terminal transferase activity in Tetrahymena extracts

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

Mammalian telomeres end in a large duplex loop

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

Telomere length dynamics and chromosomal instability in cells derived from telomerase null mice

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

Elongated Telomeres inscidMice

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

Telomere loss: mitotic clock or genetic time bomb?

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

A brief history of the mortality and immortality of cultured cells

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

The serial cultivation of human diploid cell strains

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

Sequence-specific DNA cleavage by Fe2+-mediated fenton reactions has possible biological implications

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

Ku is associated with the telomere in mammals

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

Early growth determines longevity in male rats and may be related to telomere shortening in the kidney.

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

Telomerase expression in human somatic cells does not induce changes associated with a transformed phenotype

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

DNA damage and repair in telomeres: relation to aging

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

Lessons from mice without telomerase

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

Heterogeneity in telomere length of human chromosomes.

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

Extension of cell life-span and telomere length in animals cloned from senescent somatic cells

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

Mutation of yeast Ku genes disrupts the subnuclear organization of telomeres.

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

Accumulation of short telomeres in human fibroblasts prior to replicative senescence

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

Accelerated telomere shortening in ataxia telangiectasia

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

Absence of cancer-associated changes in human fibroblasts immortalized with telomerase

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

Telomerase activity in hematopoietic cells is associated with self-renewal potential

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

A highly conserved repetitive DNA sequence, (TTAGGG)n, present at the telomeres of human chromosomes

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

Circular chromosome formation in a fission yeast mutant defective in two ATM homologues.

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

Telomere maintenance in telomerase-deficient mouse embryonic stem cells: characterization of an amplified telomeric DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

A theory of marginotomy. The incomplete copying of template margin in enzymic synthesis of polynucleotides and biological significance of the phenomenon

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

Preferential accumulation of single-stranded regions in telomeres of human fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

Longevity, Stress Response, and Cancer in Aging Telomerase-Deficient Mice

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

Telomere fluorescence measurements in granulocytes and T lymphocyte subsets point to a high turnover of hematopoietic stem cells and memory T cells in early childhood.

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

Telomere length dynamics in human lymphocyte subpopulations measured by flow cytometry.

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

Accelerated loss of telomeric repeats may not explain accelerated replicative decline of Werner syndrome cells

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

Replicative senescence: implications for in vivo aging and tumor suppression

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

Tankyrase, a poly(ADP-ribose) polymerase at human telomeres

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

Accelerated telomere shortening in the human inactive X chromosome

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

Radiosensitivity and repair of the inactive X-chromosome. Insights from FISH and immunocytogenetics

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

Telomere-telomere recombination is an efficient bypass pathway for telomere maintenance in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

TRF2 Protects Human Telomeres from End-to-End Fusions

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

ATM-dependent telomere loss in aging human diploid fibroblasts and DNA damage lead to the post-translational activation of p53 protein involving poly(ADP-ribose) polymerase.

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

Breast cancer genes and DNA repair.

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

Somatic mutations and aging: a re-evaluation

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

Origin of Concatemeric T7DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

Evidence for a new step in telomere maintenance

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

Human endothelial cell life extension by telomerase expression

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

Nuclear structure in normal and Bloom syndrome cells

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

Telomere functions: lessons from yeast.

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

Association of BRCA1 with the hRad50-hMre11-p95 complex and the DNA damage response

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

Senescence of human fibroblasts induced by oncogenic Raf.

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

Telomere length regulation in mice is linked to a novel chromosome locus.

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

Telomeres in the mouse have large inter-chromosomal variations in the number of T2AG3 repeats

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900151-2

7 January 2021

10.1016/S0047-6374(00)00151-2

Identifiers

DOI

1 reference

30 July 2017

1 reference

PubMed ID

10989122