A phenomics-based strategy identifies loci on APOC1, BRAP, and PLCG1 associated with metabolic syndrome phenotype domains (Q34055370)

30 July 2017

A phenomics-based strategy identifies loci on APOC1, BRAP, and PLCG1 associated with metabolic syndrome phenotype domains (English)

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30 July 2017

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10

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30 July 2017

5

Eric Boerwinkle

0 references

Charles Kooperberg

8

Charles Kooperberg

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30 July 2017

Jose L Ambite

4

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Sarah Pendergrass

Sarah A Pendergrass

11

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Jerome I Rotter

14

Jerome I Rotter

1 reference

30 July 2017

Qianchuan He

2

0 references

James B. Meigs

9

James B Meigs

1 reference

30 July 2017

13

Marylyn D Ritchie

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30 July 2017

17

Gerardo Heiss

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30 July 2017

12

Bruce M Psaty

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30 July 2017

6

Myriam Fornage

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30 July 2017

3

Kari E North

1 reference

30 July 2017

7

Lucia A Hindorff

1 reference

30 July 2017

15

Kent D Taylor

1 reference

30 July 2017

16

Lynne R Wilkens

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30 July 2017

1

Christy L Avery

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30 July 2017

Dan Yu Lin

18

1 reference

30 July 2017

13 October 2011

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30 July 2017

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30 July 2017

7

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10

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30 July 2017

e1002322

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Creative Commons CC0 License

30 July 2017

start time

13 October 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted, dedicated to the public domain by copyright holder

0 references

cites work

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The use of phenome-wide association studies (PheWAS) for exploration of novel genotype-phenotype relationships and pleiotropy discovery

5 July 2018

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A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium

5 July 2018

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Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels

5 July 2018

1 reference

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Phenomics: the next challenge

5 July 2018

1 reference

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MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes

5 July 2018

1 reference

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Genetic variants influencing circulating lipid levels and risk of coronary artery disease

5 July 2018

1 reference

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A genome-wide association study of the metabolic syndrome in Indian Asian men

5 July 2018

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Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

5 July 2018

1 reference

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Candidate gene association resource (CARe): design, methods, and proof of concept

5 July 2018

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Genetic studies of common types of obesity: a critique of the current use of phenotypes

5 July 2018

1 reference

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Novel associations of multiple genetic loci with plasma levels of factor VII, factor VIII, and von Willebrand factor: The CHARGE (Cohorts for Heart and Aging Research in Genome Epidemiology) Consortium

5 July 2018

1 reference

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Genome-wide association study of hematological and biochemical traits in a Japanese population

5 July 2018

1 reference

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New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

5 July 2018

1 reference

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Genetic Loci associated with C-reactive protein levels and risk of coronary heart disease

5 July 2018

1 reference

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Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations

5 July 2018

1 reference

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Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192835

Genome-wide association study of blood pressure and hypertension

5 July 2018

1 reference

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Phenomics: the systematic study of phenotypes on a genome-wide scale

5 July 2018

1 reference

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Metabolic syndrome and collateral vessel formation in patients with documented occluded coronary arteries: association with hyperglycaemia, insulin-resistance, adiponectin and plasminogen activator inhibitor-1.

5 July 2018

1 reference

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Common variants at 30 loci contribute to polygenic dyslipidemia

5 July 2018

1 reference

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Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192835

Concept, design and implementation of a cardiovascular gene-centric 50 k SNP array for large-scale genomic association studies

5 July 2018

1 reference

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5 July 2018

1 reference

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Phenomics: building scaffolds for biological hypotheses in the post-genomic era

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192835

Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192835

Newly identified loci that influence lipid concentrations and risk of coronary artery disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192835

Genetic determinants of the metabolic syndrome

5 July 2018

1 reference

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Principal components analysis corrects for stratification in genome-wide association studies

5 July 2018

1 reference

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Metabolic syndrome--a new world-wide definition. A Consensus Statement from the International Diabetes Federation

5 July 2018

1 reference

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Drug therapy of the metabolic syndrome: minimizing the emerging crisis in polypharmacy

5 July 2018

1 reference

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Regulation of vascular endothelial growth factor expression and vascularization in the myocardium by insulin receptor and PI3K/Akt pathways in insulin resistance and ischemia

5 July 2018

1 reference

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Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement

5 July 2018

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Heritabilities of the metabolic syndrome and its components in the Northern Manhattan Family Study.

5 July 2018

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Down-regulation of plasminogen activator inhibitor 1 expression promotes myocardial neovascularization by bone marrow progenitors

5 July 2018

1 reference

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Phenomics, lipodystrophy, and the metabolic syndrome

5 July 2018

1 reference

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Signal transduction: implications for Ras-dependent ERK signaling.

5 July 2018

1 reference

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Definition of metabolic syndrome: Report of the National Heart, Lung, and Blood Institute/American Heart Association conference on scientific issues related to definition

5 July 2018

1 reference

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Ras regulates assembly of mitogenic signalling complexes through the effector protein IMP

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192835

American College of Endocrinology position statement on the insulin resistance syndrome.

5 July 2018

1 reference

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The human phenome project

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192835

Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192835

Absence of erythrogenesis and vasculogenesis in Plcg1-deficient mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192835

Protection from obesity and insulin resistance in mice overexpressing human apolipoprotein C1.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192835

Cardiovascular morbidity and mortality associated with the metabolic syndrome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192835

Invited commentary: insulin resistance syndrome? Syndrome X? Multiple metabolic syndrome? A syndrome at all? Factor analysis reveals patterns in the fabric of correlated metabolic risk factors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192835

Pancreatic beta-cell glucokinase: closing the gap between theoretical concepts and experimental realities.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192835

Identification of a novel cytoplasmic protein that specifically binds to nuclear localization signal motifs

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192835

Multiple trait analysis of genetic mapping for quantitative trait loci.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192835

Inositol trisphosphate, a novel second messenger in cellular signal transduction

5 July 2018

1 reference

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The apolipoprotein multigene family: biosynthesis, structure, structure-function relationships, and evolution.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192835

Effect of the human plasma apolipoproteins and phosphatidylcholine acyl donor on the activity of lecithin. Cholesterol acyltransferase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192835

Functional variants in ADH1B and ALDH2 coupled with alcohol and smoking synergistically enhance esophageal cancer risk

5 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002322

A large-scale genome-wide association study of Asian populations uncovers genetic factors influencing eight quantitative traits.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002322

Insulin receptor and lipid metabolism pathology in ataxin-2 knock-out mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002322

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002322

Prevalence and characteristics of the metabolic syndrome in the San Antonio Heart and Framingham Offspring Studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002322

Genome-wide association study for C-reactive protein levels identified pleiotropic associations in the IL6 locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002322

A comparison of univariate and multivariate tests for genetic linkage

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22022282

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Comment on the provisional report from the WHO consultation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22022282

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Common familial influences on clustering of metabolic syndrome traits with central obesity and insulin resistance: the Kiel obesity prevention study

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22022282

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PGEN.1002322

1 reference

30 July 2017

1 reference

30 July 2017

1 reference

PubMed ID

22022282