Inactivation of SOCS3 in leptin receptor-expressing cells protects mice from diet-induced insulin resistance but does not prevent obesity (Q34080577)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25161884%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

title

Inactivation of SOCS3 in leptin receptor-expressing cells protects mice from diet-induced insulin resistance but does not prevent obesity (English)

1 reference

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14 March 2020

0 references

1 reference

1 reference

1

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14 March 2020

Carol F Elias

7

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14 March 2020

Jose Donato

8

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14 March 2020

author name string

Daniella C Buonfiglio

2

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14 March 2020

Lais I Cardinali

3

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14 March 2020

Isadora C Furigo

4

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14 March 2020

Angela M Ramos-Lobo

5

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Julio Tirapegui

6

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14 March 2020

publication date

12 June 2014

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14 March 2020

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14 March 2020

volume

3

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14 March 2020

issue

6

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14 March 2020

page(s)

608-618

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Improved metabolic phenotype of hypothalamic PTP1B-deficiency is dependent upon the leptin receptor.

14 March 2020

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Combined neural inactivation of suppressor of cytokine signaling-3 and protein-tyrosine phosphatase-1B reveals additive, synergistic, and factor-specific roles in the regulation of body energy balance

5 July 2018

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Nestin-Cre mice are affected by hypopituitarism, which is not due to significant activity of the transgene in the pituitary gland.

5 July 2018

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Segregation of acute leptin and insulin effects in distinct populations of arcuate proopiomelanocortin neurons

5 July 2018

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Functional role of suppressor of cytokine signaling 3 upregulation in hypothalamic leptin resistance and long-term energy homeostasis.

5 July 2018

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Phosphatidyl inositol 3-kinase signaling in hypothalamic proopiomelanocortin neurons contributes to the regulation of glucose homeostasis

5 July 2018

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Palmitic acid mediates hypothalamic insulin resistance by altering PKC-theta subcellular localization in rodents

5 July 2018

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Recent advances in understanding leptin signaling and leptin resistance

5 July 2018

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5 July 2018

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SOCS-1 deficiency does not prevent diet-induced insulin resistance

5 July 2018

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Selective inactivation of Socs3 in SF1 neurons improves glucose homeostasis without affecting body weight

5 July 2018

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Mice lacking inhibitory leptin receptor signals are lean with normal endocrine function

5 July 2018

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Attenuation of leptin and insulin signaling by SOCS proteins

5 July 2018

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Complete rescue of obesity, diabetes, and infertility in db/db mice by neuron-specific LEPR-B transgenes

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Leptin treatment increases suppressors of cytokine signaling in central and peripheral tissues

5 July 2018

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5 July 2018

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Identification of SOCS-3 as a potential mediator of central leptin resistance

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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28 October 2018

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Protein tyrosine phosphatase epsilon affects body weight by downregulating leptin signaling in a phosphorylation-dependent manner.

28 October 2018

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Glucose sensing by POMC neurons regulates glucose homeostasis and is impaired in obesity.

28 October 2018

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Enhanced leptin sensitivity and improved glucose homeostasis in mice lacking suppressor of cytokine signaling-3 in POMC-expressing cells.

28 October 2018

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Socs3 deficiency in the brain elevates leptin sensitivity and confers resistance to diet-induced obesity

28 October 2018

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ATP-sensitive K+ channels in the hypothalamus are essential for the maintenance of glucose homeostasis.

28 October 2018

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Divergent roles of SHP-2 in ERK activation by leptin receptors

28 October 2018

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28 October 2018

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Insulin activates ATP-sensitive K+ channels in hypothalamic neurons of lean, but not obese rats

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25161884

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Differential expression of hypothalamic neuropeptides in the early phase of diet-induced obesity in mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25161884

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.MOLMET.2014.06.001

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25161884%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25161884%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25161884%20AND%20SRC:MED&resulttype=core&format=json