The transforming growth factor-betas: structure, signaling, and roles in nervous system development and functions (Q34083587)

30 July 2017

1 reference

title

The transforming growth factor-betas: structure, signaling, and roles in nervous system development and functions (English)

1 reference

30 July 2017

0 references

Böttner M

1

1 reference

30 July 2017

Krieglstein K

series ordinal

2

1 reference

30 July 2017

Unsicker K

series ordinal

3

1 reference

30 July 2017

language of work or name

English

0 references

publication date

1 December 2000

1 reference

Journal of Neurochemistry

30 July 2017

1 reference

30 July 2017

75

1 reference

30 July 2017

2227-2240

1 reference

30 July 2017

6

1 reference

Transforming growth factor-beta 1 promotes re-elongation of injured axons of cultured rat hippocampal neurons

30 July 2017

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Activation of signalling by the activin receptor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Artemin, a novel member of the GDNF ligand family, supports peripheral and central neurons and signals through the GFRalpha3-RET receptor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Source of the anti-Müllerian hormone synthesized by the fetal testis: Müllerian-inhibiting activity of fetal bovine Sertoli cells in tissue culture.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Evolution of the transforming growth factor-beta superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Developmental regulation of neuronal K+ channels by target-derived TGF beta in vivo and in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Extracellular modulation of the Hedgehog, Wnt and TGF-beta signalling pathways during embryonic development

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Tumor necrosis factor-alpha mediates the release of bioactive transforming growth factor-beta in murine microglial cell cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Smad4 and FAST-1 in the assembly of activin-responsive factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Regulation of transforming growth factor beta- and activin-induced transcription by mammalian Mad proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Pioneer axon guidance by UNC-129, a C. elegans TGF-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Transient production of TGF-beta 2 by postnatal cerebellar neurons and its effect on neuroblast proliferation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Transforming growth factor-beta 1 (TGF-β1) expression and regulation in rat cortical astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Glial cell-specific mechanisms of TGF-beta 1 induction by IL-1 in cerebral cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Crystal structure of transforming growth factor-beta 2: an unusual fold for the superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

GDNF signalling through the Ret receptor tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Bone morphogenetic proteins and their receptors: potential functions in the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Molecular profile of reactive astrocytes--implications for their role in neurologic disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

The tumor suppressor Smad4/DPC4 and transcriptional adaptor CBP/p300 are coactivators for smad3 in TGF-beta-induced transcriptional activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Decapentaplegic acts as a morphogen to organize dorsal-ventral pattern in the Drosophila embryo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

TGF-beta 1 is an organizer of responses to neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Effects of TGF-betas and bFGF on Astroglial Cell Growth and Gene Expression in Vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Altered expression of transforming growth factor-beta in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Transforming growth factor-betas in neurodegenerative disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Cytokine-induced changes in the ability of astrocytes to support migration of oligodendrocyte precursors and axon growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

The GS domain of the transforming growth factor-beta type I receptor is important in signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Rapid TGF beta 1 effects on actin cytoskeleton of astrocytes: comparison with other factors and implications for cell motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Regulation of the transmitter phenotype of rostral and caudal groups of cultured serotonergic raphe neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Three-dimensional structure of recombinant human osteogenic protein 1: structural paradigm for the transforming growth factor beta superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Central nervous system neuronal migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

TGF-beta signalling from cell membrane to nucleus through SMAD proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Transforming growth factor beta 1: three-dimensional structure in solution and comparison with the X-ray structure of transforming growth factor beta 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Distinctive patterns of PDGF-A, FGF-2, IGF-I, and TGF-beta1 gene expression during remyelination of experimentally-induced spinal cord demyelination.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Bone morphogenetic proteins: multifunctional regulators of vertebrate development

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Transforming growth factor-betas inhibit mitogen-stimulated proliferation of astrocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Tumor necrosis factor alpha induces adhesion molecule expression on human fetal astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Smad6 inhibits signalling by the TGF-beta superfamily.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Transforming growth factor-beta 1 and -beta 2 promote neurite sprouting and elongation of cultured rat hippocampal neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Transforming growth factor beta1 induces nuclear export of inhibitory Smad7

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

GFRalpha-2 and GFRalpha-3 are two new receptors for ligands of the GDNF family

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Transforming growth factor-beta 1 differentially regulates proliferation and MHC class-II antigen expression in forebrain and brainstem astrocyte primary cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Serine/threonine kinase receptors and ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Transforming growth factor-beta 1: a lesion-associated cytokine of the nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

The TGF-beta superfamily: new members, new receptors, and new genetic tests of function in different organisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Detection of ebaf, a novel human gene of the transforming growth factor beta superfamily association of gene expression with endometrial bleeding

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Neurturin, a relative of glial-cell-line-derived neurotrophic factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

SMADs: mediators and regulators of TGF-beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

The TGF-beta family mediator Smad1 is phosphorylated directly and activated functionally by the BMP receptor kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Transforming growth factor-beta promotes survival of midbrain dopaminergic neurons and protects them against N-methyl-4-phenylpyridinium ion toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Distinct modulatory actions of TGF-beta and LIF on neurotrophin-mediated survival of developing sensory neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Neural functions of the transforming growth factors beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Transforming growth factor type beta 1 modulates the effects of basic fibroblast growth factor on growth and phenotypic expression of rat astroblasts in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Partnership between DPC4 and SMAD proteins in TGF-beta signalling pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

The specification of dorsal cell fates in the vertebrate central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Transforming growth factor-beta 1 in the rat brain: increase after injury and inhibition of astrocyte proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Isolation and partial characterization of a Mr 32,000 protein with inhibin activity from porcine follicular fluid

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Human type II receptor for bone morphogenic proteins (BMPs): extension of the two-kinase receptor model to the BMPs

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

A human Mad protein acting as a BMP-regulated transcriptional activator

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Ubiquitin-dependent degradation of TGF-beta-activated smad2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Betaglycan presents ligand to the TGF beta signaling receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

MADR2 is a substrate of the TGFbeta receptor and its phosphorylation is required for nuclear accumulation and signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Transforming growth factor-beta 2: cDNA cloning and sequence analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Transforming growth factor beta 1 is a potent survival factor for rat embryo motoneurons in culture.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

The transforming growth factor-beta family

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

TGF-beta signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

A structural superfamily of growth factors containing a cystine knot motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

A role for TGF-beta in oligodendrocyte differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Bone morphogenetic proteins in the nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Left-right asymmetric expression of the TGF beta-family member lefty in mouse embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Persephin, a novel neurotrophic factor related to GDNF and neurturin

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Immunohistochemical localization of TGF beta 1, TGF beta 2, and TGF beta 3 in the mouse embryo: expression patterns suggest multiple roles during embryonic development

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Inhibin and activin modulate the release of gonadotropin-releasing hormone, human chorionic gonadotropin, and progesterone from cultured human placental cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

TGF beta 2 and TGF beta 3 are potent survival factors for midbrain dopaminergic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

TGF-beta in the central nervous system: potential roles in ischemic injury and neurodegenerative diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Control of C. elegans larval development by neuronal expression of a TGF-beta homolog

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

New class of transforming growth factors potentiated by epidermal growth factor: isolation from non-neoplastic tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Floor plate and motor neuron induction by different concentrations of the amino-terminal cleavage product of sonic hedgehog autoproteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

In vivo protection of nigral dopamine neurons by lentiviral gene transfer of the novel GDNF-family member neublastin/artemin

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Cloning and characterization of a human type II receptor for bone morphogenetic proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Caenorhabditis elegans genes sma-2, sma-3, and sma-4 define a conserved family of transforming growth factor beta pathway components

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Transforming growth factors type beta 1 and beta 2 suppress rat astrocyte autoantigen presentation and antagonize hyperinduction of class II major histocompatibility complex antigen expression by interferon-gamma and tumor necrosis factor-alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

An unusual feature revealed by the crystal structure at 2.2 A resolution of human transforming growth factor-beta 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Expression of DSD-1-PG in primary neural and glial-derived cell line cultures, upregulation by TGF-beta, and implications for cell-substrate interactions of the glial cell line Oli-neu

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Alternative neural crest cell fates are instructively promoted by TGFbeta superfamily members

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Regulation of intercellular adhesion molecule-1 gene expression by tumor necrosis factor-alpha, interleukin-1 beta, and interferon-gamma in astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Identification of a potent Xenopus mesoderm-inducing factor as a homologue of activin A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

The cystine-knot growth-factor superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

GFRalpha-4, a new GDNF family receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Processed Vg1 protein is an axial mesoderm inducer in Xenopus

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Effects of transforming growth factor beta 1 on astroglial cells in culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Characterization of a multicomponent receptor for GDNF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Functional receptor for GDNF encoded by the c-ret proto-oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

SARA, a FYVE domain protein that recruits Smad2 to the TGFbeta receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Growth factors in chromaffin cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Transforming growth factor beta isoforms in the adult rat central and peripheral nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Expression, localization, and function of transforming growth factor-beta s in embryonic chick spinal cord, hindbrain, and dorsal root ganglia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Purification and characterization of an FSH releasing protein from porcine ovarian follicular fluid

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Spontaneously increased production of nitric oxide and aberrant expression of the inducible nitric oxide synthase in vivo in the transforming growth factor beta 1 null mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Transforming growth factor beta (TGF-?) in inflammation: A cause and a cure

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

A maternal mRNA localized to the vegetal hemisphere in Xenopus eggs codes for a growth factor related to TGF-beta.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Transforming growth factor-β, but not ciliary neurotrophic factor, inhibits DNA synthesis of adrenal medullary cells in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

A Smad transcriptional corepressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Novel regulators of bone formation: molecular clones and activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

TGF beta signals through a heteromeric protein kinase receptor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Mechanism of activation of the TGF-beta receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Transforming growth factor-beta1 induces apoptosis of rat microglia without relation to bcl-2 oncoprotein expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Receptor-associated Mad homologues synergize as effectors of the TGF-beta response

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Nodal is a novel TGF-beta-like gene expressed in the mouse node during gastrulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

Two forms of transforming growth factor-β distinguished by multipotential haematopoietic progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.2000.0752227.X

10.1046/J.1471-4159.2000.0752227.X

21 January 2018

Identifiers

DOI

1 reference

30 July 2017

1 reference