Pancreatic cancer and its stroma: a conspiracy theory (Q34093809)

31 July 2017

Pancreatic cancer and its stroma: a conspiracy theory (English)

1 reference

31 July 2017

1 reference

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25170206%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Jeremy S. Wilson

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25170206%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Minoti V. Apte

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25170206%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

author name string

Zhihong Xu

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25170206%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

language of work or name

English

0 references

publication date

1 August 2014

1 reference

World Journal of Gastroenterology

31 July 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25170206%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

volume

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25170206%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

page(s)

11216-11229

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25170206%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

issue

32

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25170206%20AND%20SRC:MED&resulttype=core&format=json

Migratory activity of CD105+ pancreatic cancer cells is strongly enhanced by pancreatic stellate cells

31 May 2020

cites work

1 reference

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Angiotensin inhibition enhances drug delivery and potentiates chemotherapy by decompressing tumour blood vessels

5 July 2018

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Inhibition of pancreatic carcinoma by homo- and heterocombinations of antibodies against EGF-receptor and its kin HER2/ErbB-2

5 July 2018

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Activated pancreatic stellate cells sequester CD8+ T cells to reduce their infiltration of the juxtatumoral compartment of pancreatic ductal adenocarcinoma

5 July 2018

1 reference

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Tumour-stroma interactions in pancreatic ductal adenocarcinoma: rationale and current evidence for new therapeutic strategies

5 July 2018

1 reference

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nab-Paclitaxel mechanisms of action and delivery

5 July 2018

1 reference

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Stromal expression of SPARC in pancreatic adenocarcinoma

5 July 2018

1 reference

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Therapeutic advances in pancreatic cancer

5 July 2018

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A starring role for stellate cells in the pancreatic cancer microenvironment

5 July 2018

1 reference

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Phase I study of the Hedgehog pathway inhibitor IPI-926 in adult patients with solid tumors

5 July 2018

1 reference

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The angiotensin II type I receptor blocker olmesartan inhibits the growth of pancreatic cancer by targeting stellate cell activities in mice

5 July 2018

1 reference

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Immune cell infiltration as an indicator of the immune microenvironment of pancreatic cancer

5 July 2018

1 reference

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5 July 2018

Cancer statistics, 2013

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p53-independent roles of MDM2 in NF-κB signaling: implications for cancer therapy, wound healing, and autoimmune diseases

5 July 2018

1 reference

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Stellate cells from rat pancreas are stem cells and can contribute to liver regeneration

5 July 2018

1 reference

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Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes

5 July 2018

1 reference

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CXCL12/CXCR4 protein signaling axis induces sonic hedgehog expression in pancreatic cancer cells via extracellular regulated kinase- and Akt kinase-mediated activation of nuclear factor κB: implications for bidirectional tumor-stromal interactions

5 July 2018

1 reference

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Pancreatic stellate cells: a starring role in normal and diseased pancreas

5 July 2018

1 reference

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Inhibition of the hedgehog pathway targets the tumor-associated stroma in pancreatic cancer

5 July 2018

1 reference

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Stromal galectin-1 expression is associated with long-term survival in resectable pancreatic ductal adenocarcinoma

5 July 2018

1 reference

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Tumor-derived granulocyte-macrophage colony-stimulating factor regulates myeloid inflammation and T cell immunity in pancreatic cancer.

5 July 2018

1 reference

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Pancreatic stellate cells enhance stem cell-like phenotypes in pancreatic cancer cells

5 July 2018

1 reference

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Syndecan-2 promotes perineural invasion and cooperates with K-ras to induce an invasive pancreatic cancer cell phenotype

5 July 2018

1 reference

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Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer

5 July 2018

1 reference

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Enzymatic targeting of the stroma ablates physical barriers to treatment of pancreatic ductal adenocarcinoma

5 July 2018

1 reference

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An NF-κB pathway-mediated positive feedback loop amplifies Ras activity to pathological levels in mice.

5 July 2018

1 reference

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Epidemiology, risk factors, and the promotion of pancreatic cancer: role of the stellate cell

5 July 2018

1 reference

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Dangerous liaisons: pancreatic stellate cells and pancreatic cancer cells

5 July 2018

1 reference

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Trefoil factor family peptides in normal and diseased human pancreas.

5 July 2018

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Cancers with increasing incidence trends in the United States: 1999 through 2008.

5 July 2018

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Oncogenic Kras is required for both the initiation and maintenance of pancreatic cancer in mice

5 July 2018

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Galectin-1 research in T cell immunity: past, present and future

5 July 2018

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Gemcitabine plus nab-paclitaxel is an active regimen in patients with advanced pancreatic cancer: a phase I/II trial

5 July 2018

1 reference

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Inhibiting Cxcr2 disrupts tumor-stromal interactions and improves survival in a mouse model of pancreatic ductal adenocarcinoma

5 July 2018

1 reference

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Trefoil factor 1 stimulates both pancreatic cancer and stellate cells and increases metastasis

5 July 2018

1 reference

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Precursor lesions in pancreatic cancer: morphological and molecular pathology.

5 July 2018

1 reference

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CD40 agonists alter tumor stroma and show efficacy against pancreatic carcinoma in mice and humans

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4145760

5 July 2018

Global cancer statistics

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Malignant cells facilitate lung metastasis by bringing their own soil

5 July 2018

1 reference

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Molecular biology of pancreatic ductal adenocarcinoma progression: aberrant activation of developmental pathways

5 July 2018

1 reference

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Suppression of antitumor immunity by stromal cells expressing fibroblast activation protein-alpha

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4145760

Inhibition of renin-angiotensin system affects prognosis of advanced pancreatic cancer receiving gemcitabine

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4145760

Role of pancreatic stellate cells in pancreatic cancer metastasis.

5 July 2018

1 reference

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KRAS, Hedgehog, Wnt and the twisted developmental biology of pancreatic ductal adenocarcinoma.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4145760

CD10+ pancreatic stellate cells enhance the progression of pancreatic cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4145760

Molecular mechanism of pancreatic cancer--understanding proliferation, invasion, and metastasis

5 July 2018

1 reference

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Ras activity in acinar cells links chronic pancreatitis and pancreatic cancer

5 July 2018

1 reference

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Germ-line mutations, pancreatic inflammation, and pancreatic cancer

5 July 2018

1 reference

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Organotypic culture model of pancreatic cancer demonstrates that stromal cells modulate E-cadherin, beta-catenin, and Ezrin expression in tumor cells

5 July 2018

1 reference

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Inflammation and pancreatic cancer: an evidence-based review

5 July 2018

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Ras activity levels control the development of pancreatic diseases.

5 July 2018

1 reference

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Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer

5 July 2018

1 reference

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Identification of a pancreatic stellate cell population with properties of progenitor cells: new role for stellate cells in the pancreas.

5 July 2018

1 reference

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Quantitative proteomics investigation of pancreatic intraepithelial neoplasia

5 July 2018

1 reference

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The pathology and genetics of metastatic pancreatic cancer

5 July 2018

1 reference

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Sonic hedgehog promotes desmoplasia in pancreatic cancer

5 July 2018

1 reference

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Seeding and propagation of untransformed mouse mammary cells in the lung

5 July 2018

1 reference

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Pancreatic stellate cells: partners in crime with pancreatic cancer cells

5 July 2018

1 reference

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The role of nuclear factor kappaB in pancreatic cancer and the clinical applications of targeted therapy.

5 July 2018

1 reference

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Cancer-associated stromal fibroblasts promote pancreatic tumor progression

5 July 2018

1 reference

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The integrin-extracellular matrix axis in pancreatic cancer

5 July 2018

1 reference

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Bacterial endotoxin: a trigger factor for alcoholic pancreatitis? Evidence from a novel, physiologically relevant animal model

5 July 2018

1 reference

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Tumor microvasculature and microenvironment: targets for anti-angiogenesis and normalization

5 July 2018

1 reference

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Suppression of pancreatic tumor growth by combination chemotherapy with sulindac and LC-1 is associated with cyclin D1 inhibition in vivo.

5 July 2018

1 reference

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Periostin creates a tumor-supportive microenvironment in the pancreas by sustaining fibrogenic stellate cell activity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4145760

Stromal biology of pancreatic cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4145760

The alpha2beta1 integrin mediates the malignant phenotype on type I collagen in pancreatic cancer cell lines

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4145760

Hedgehog signaling in the normal and diseased pancreas

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4145760

Pancreatic stellate cells (PSCs) express cyclooxygenase-2 (COX-2) and pancreatic cancer stimulates COX-2 in PSCs

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4145760

Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice

5 July 2018

1 reference

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Pancreatic carcinoma cells induce fibrosis by stimulating proliferation and matrix synthesis of stellate cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4145760

Precursors to invasive pancreatic cancer

5 July 2018

1 reference

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Desmoplastic reaction in pancreatic cancer: role of pancreatic stellate cells

5 July 2018

1 reference

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Inflammation and Cancer V. Chronic pancreatitis and pancreatic cancer

5 July 2018

1 reference

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Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis

5 July 2018

1 reference

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K-Ras mutations and benign pancreatic disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4145760

Cyclo-oxygenase isoenzymes: physiological and pharmacological role

5 July 2018

1 reference

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Periacinar stellate shaped cells in rat pancreas: identification, isolation, and culture.

5 July 2018

1 reference

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Risk of pancreatic carcinoma in tropical calcifying pancreatitis: an epidemiologic study

5 July 2018

1 reference

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Activation of nuclear factor-κB in acinar cells increases the severity of pancreatitis in mice

5 July 2018

1 reference

https://api.crossref.org/works/10.3748%2FWJG.V20.I32.11216

Pancreatitis-induced inflammation contributes to pancreatic cancer by inhibiting oncogene-induced senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.3748%2FWJG.V20.I32.11216

The activated stroma index is a novel and independent prognostic marker in pancreatic ductal adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.3748%2FWJG.V20.I32.11216

Synthetic extracellular matrix enhances tumor growth and metastasis in an orthotopic mouse model of pancreatic adenocarcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.3748%2FWJG.V20.I32.11216

Hypoxia stimulates pancreatic stellate cells to induce fibrosis and angiogenesis in pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3748%2FWJG.V20.I32.11216

Delayed progression of pancreatic intraepithelial neoplasia in a conditional Kras(G12D) mouse model by a selective cyclooxygenase-2 inhibitor.

21 January 2018

1 reference

https://api.crossref.org/works/10.3748%2FWJG.V20.I32.11216

Hedgehog inhibition prolongs survival in a genetically engineered mouse model of pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3748%2FWJG.V20.I32.11216

Pirfenidone inhibits pancreatic cancer desmoplasia by regulating stellate cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3748%2FWJG.V20.I32.11216

Angiotensin II stimulates DNA synthesis of rat pancreatic stellate cells by activating ERK through EGF receptor transactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.3748%2FWJG.V20.I32.11216

Cancer-stellate cell interactions perpetuate the hypoxia-fibrosis cycle in pancreatic ductal adenocarcinoma

21 January 2018

1 reference

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Advanced Pancreatic Ductal Cancer: Fibrotic Focus and β-Catenin Expression Correlate With Outcome

28 October 2018

1 reference

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Identification, culture, and characterization of pancreatic stellate cells in rats and humans.

28 October 2018

1 reference

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Incidence and survival for hepatic, pancreatic and biliary cancers in England between 1998 and 2007

28 October 2018

1 reference

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Chronic Pancreatitis Is Essential for Induction of Pancreatic Ductal Adenocarcinoma by K-Ras Oncogenes in Adult Mice

21 January 2018

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12 December 2020

Hereditary pancreatitis and secondary screening for early pancreatic cancer

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12 December 2020

Isolation of quiescent human pancreatic stellate cells: a promising in vitro tool for studies of human pancreatic stellate cell biology

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12 December 2020

High expression of Galectin-1 in pancreatic stellate cells plays a role in the development and maintenance of an immunosuppressive microenvironment in pancreatic cancer

1 reference

12 December 2020

Periostin deposition in the stroma of invasive and intraductal neoplasms of the pancreas

1 reference

12 December 2020

The pre-clinical absorption, distribution, metabolism and excretion properties of IPI-926, an orally bioavailable antagonist of the hedgehog signal transduction pathway

1 reference

12 December 2020

10.3748/WJG.V20.I32.11216

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25170206%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25170206%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25170206%20AND%20SRC:MED&resulttype=core&format=json