New mimetic peptides of the kinase-inhibitory region (KIR) of SOCS1 through focused peptide libraries (Q34099855)

31 July 2017

title

New mimetic peptides of the kinase-inhibitory region (KIR) of SOCS1 through focused peptide libraries (English)

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31 July 2017

Nunzianna Doti

1

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31 July 2017

Pasqualina L Scognamiglio

2

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31 July 2017

Stefania Madonna

3

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31 July 2017

Claudia Scarponi

4

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31 July 2017

Menotti Ruvo

5

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31 July 2017

Giuseppe Perretta

6

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31 July 2017

Cristina Albanesi

7

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31 July 2017

Daniela Marasco

8

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31 July 2017

language of work or name

English

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publication date

1 April 2012

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31 July 2017

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31 July 2017

volume

443

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31 July 2017

issue

1

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31 July 2017

page(s)

231-240

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Signaling through the hematopoietic cytokine receptors.

31 July 2017

cites work

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Cytokine-inducible SH2 protein-3 (CIS3/SOCS3) inhibits Janus tyrosine kinase by binding through the N-terminal kinase inhibitory region as well as SH2 domain

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The role of suppressors of cytokine signaling (SOCS) proteins in regulation of the immune response

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Inhibitors of cytokine signal transduction

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Regulation of SOCS-1 expression by translational repression

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A new protein containing an SH2 domain that inhibits JAK kinases

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Regulation of Jak2 through the ubiquitin-proteasome pathway involves phosphorylation of Jak2 on Y1007 and interaction with SOCS-1.

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SOCS1 is a critical inhibitor of interferon gamma signaling and prevents the potentially fatal neonatal actions of this cytokine.

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SOCS1 deficiency causes a lymphocyte-dependent perinatal lethality

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Controlling nuclear JAKs and STATs for specific gene activation by IFNγ.

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Suppressor of cytokine signaling-3 preferentially binds to the SHP-2-binding site on the shared cytokine receptor subunit gp130

21 January 2018

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The JAK-binding protein JAB inhibits Janus tyrosine kinase activity through binding in the activation loop

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A three-dimensional model of Suppressor Of Cytokine Signalling 1 (SOCS-1).

21 January 2018

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A SOCS-1 peptide mimetic inhibits both constitutive and IL-6 induced activation of STAT3 in prostate cancer cells.

21 January 2018

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The IFN-gamma-dependent suppressor of cytokine signaling 1 promoter activity is positively regulated by IFN regulatory factor-1 and Sp1 but repressed by growth factor independence-1b and Krüppel-like factor-4, and it is dysregulated in psoriatic ker

21 January 2018

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SOCS-1 mimetics protect mice against lethal poxvirus infection: identification of a novel endogenous antiviral system

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Past and future perspectives of synthetic peptide libraries

21 January 2018

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Discovery of small peptide antagonists of PED/PEA15-D4α interaction from simplified combinatorial libraries

21 January 2018

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Cytomegalovirus in autoimmunity: T cell crossreactivity to viral antigen and autoantigen glutamic acid decarboxylase

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Selection of estrogen receptor beta- and thyroid hormone receptor beta-specific coactivator-mimetic peptides using recombinant peptide libraries

21 January 2018

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Generating Diverse Skeletons of Small Molecules Combinatorially

21 January 2018

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Triggered enzymatic degradation of a water-soluble polymer solution using a novel inhibitor

21 January 2018

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A priori delineation of a peptide which mimics a discontinuous antigenic determinant

21 January 2018

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VE-cadherin-derived cell-penetrating peptide, pVEC, with carrier functions

21 January 2018

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Effects of etanercept on quality of life, fatigue, and depression in psoriasis.

21 January 2018

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Regulation of innate immunity by suppressor of cytokine signaling (SOCS) proteins

21 January 2018

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SOCS proteins, cytokine signalling and immune regulation

21 January 2018

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The SOCS box encodes a hierarchy of affinities for Cullin5: implications for ubiquitin ligase formation and cytokine signalling suppression

21 January 2018

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Suppressors of cytokine signaling and immunity

21 January 2018

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A TEL-JAK2 fusion protein with constitutive kinase activity in human leukemia

21 January 2018

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21 January 2018

Identifiers

DOI

10.1042/BJ20111647

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31 July 2017

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