Indispensable roles of OX40L-derived signal and epistatic genetic effect in immune-mediated pathogenesis of spontaneous pulmonary hypertension (Q34101823)

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English	Indispensable roles of OX40L-derived signal and epistatic genetic effect in immune-mediated pathogenesis of spontaneous pulmonary hypertension	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

31 July 2017

Indispensable roles of OX40L-derived signal and epistatic genetic effect in immune-mediated pathogenesis of spontaneous pulmonary hypertension (English)

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Europe PubMed Central

PubMed publication ID

31 July 2017

author name string

Moloud Rabieyousefi

1

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31 July 2017

Pejman Soroosh

2

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31 July 2017

Kimio Satoh

3

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31 July 2017

Fumiko Date

4

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31 July 2017

Naoto Ishii

5

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31 July 2017

Masahiro Yamashita

6

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31 July 2017

Masahiko Oka

7

1 reference

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31 July 2017

Ivan F McMurtry

8

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31 July 2017

Hiroaki Shimokawa

9

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31 July 2017

Masato Nose

10

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31 July 2017

Kazuo Sugamura

11

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31 July 2017

Masao Ono

12

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31 July 2017

publication date

15 December 2011

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31 July 2017

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31 July 2017

12

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31 July 2017

67

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31 July 2017

Pulmonary arterial remodeling induced by a Th2 immune response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269997

5 July 2018

Absence of T cells confers increased pulmonary arterial hypertension and vascular remodeling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269997

5 July 2018

Regulatory T cells dampen pulmonary inflammation and lung injury in an animal model of pneumocystis pneumonia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269997

5 July 2018

OX40-OX40 ligand interaction through T cell-T cell contact contributes to CD4 T cell longevity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269997

5 July 2018

Autoimmunity and pulmonary hypertension: a perspective

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269997

5 July 2018

CD4+CD25+ T cells protect against experimentally induced asthma and alter pulmonary dendritic cell phenotype and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269997

5 July 2018

Development of occlusive neointimal lesions in distal pulmonary arteries of endothelin B receptor-deficient rats: a new model of severe pulmonary arterial hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269997

5 July 2018

Cellular and molecular pathobiology of pulmonary arterial hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269997

5 July 2018

Therapeutic targeting of the effector T-cell co-stimulatory molecule OX40.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269997

5 July 2018

Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269997

5 July 2018

Co-stimulatory members of the TNFR family: keys to effective T-cell immunity?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269997

5 July 2018

Inflammation in pulmonary arterial hypertension.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269997

5 July 2018

IL-17 production from activated T cells is required for the spontaneous development of destructive arthritis in mice deficient in IL-1 receptor antagonist

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269997

5 July 2018

Increased expression of interleukin 17 in inflammatory bowel disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269997

5 July 2018

Nitric oxide preferentially induces type 1 T cell differentiation by selectively up-regulating IL-12 receptor beta 2 expression via cGMP

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269997

5 July 2018

Signaling of gp34 (OX40 ligand) induces vascular endothelial cells to produce a CC chemokine RANTES/CCL5.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269997

5 July 2018

IL-13-induced chemokine responses in the lung: role of CCR2 in the pathogenesis of IL-13-induced inflammation and remodeling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269997

5 July 2018

Genetic aspects of pulmonary arterial hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269997

5 July 2018

OX40 promotes Bcl-xL and Bcl-2 expression and is essential for long-term survival of CD4 T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269997

5 July 2018

eNOS-deficient mice show reduced pulmonary vascular proliferation and remodeling to chronic hypoxia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269997

5 July 2018

Familial primary pulmonary hypertension (gene PPH1) is caused by mutations in the bone morphogenetic protein receptor-II gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269997

5 July 2018

Impairment of antigen-presenting cell function in mice lacking expression of OX40 ligand

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269997

5 July 2018

IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269997

5 July 2018

Sustained pulmonary hypertension and right ventricular hypertrophy after chronic hypoxia in mice with congenital deficiency of nitric oxide synthase 3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269997

5 July 2018

CD28/B7 system of T cell costimulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269997

5 July 2018

Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269997

5 July 2018

Calculating confidence intervals for relative risks (odds ratios) and standardised ratios and rates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269997

5 July 2018

Pulmonary inflammation and emphysema: role of the cytokines IL-18 and IL-13.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2172-12-67

21 January 2018

Endothelial cell co-stimulation through OX40 augments and prolongs T cell cytokine synthesis by stabilization of cytokine mRNA.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2172-12-67

21 January 2018

Important role of endogenous erythropoietin system in recruitment of endothelial progenitor cells in hypoxia-induced pulmonary hypertension in mice

1 reference

https://api.crossref.org/works/10.1186%2F1471-2172-12-67

21 January 2018

Positional identification of TNFSF4, encoding OX40 ligand, as a gene that influences atherosclerosis susceptibility

1 reference

https://api.crossref.org/works/10.1186%2F1471-2172-12-67

21 January 2018

Interruption of the Tnfrsf4/Tnfsf4 (OX40/OX40L) pathway attenuates atherogenesis in low-density lipoprotein receptor-deficient mice.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2172-12-67

21 January 2018

Hepatocyte growth factor suppresses vascular medial hyperplasia and matrix accumulation in advanced pulmonary hypertension of rats

1 reference

https://api.crossref.org/works/10.1186%2F1471-2172-12-67

21 January 2018

Hepatocyte growth factor attenuates airway hyperresponsiveness, inflammation, and remodeling

1 reference

https://api.crossref.org/works/10.1186%2F1471-2172-12-67

21 January 2018

Differential requirements for OX40 signals on generation of effector and central memory CD4+ T cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269997

28 October 2018

Distinct roles for the OX40-OX40 ligand interaction in regulatory and nonregulatory T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269997

28 October 2018

Lung CD25 CD4 regulatory T cells suppress type 2 immune responses but not bronchial hyperreactivity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269997

28 October 2018

Constitutive OX40/OX40 ligand interaction induces autoimmune-like diseases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269997

28 October 2018

Positive association of the endothelial nitric oxide synthase gene polymorphisms with high-altitude pulmonary edema

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269997

28 October 2018

Tissue-level regulation of Th1 and Th2 primary and memory CD4 T cells in response to Listeria infection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269997

28 October 2018

Danger and OX40 receptor signaling synergize to enhance memory T cell survival by inhibiting peripheral deletion

1 reference

https://pubmed.ncbi.nlm.nih.gov/22171643

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Critical role for OX40 ligand in the development of pathogenic Th2 cells in a murine model of asthma

1 reference

https://pubmed.ncbi.nlm.nih.gov/22171643

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-endothelial cell antibodies in mixed connective tissue disease: frequency and association with clinical symptoms

1 reference

https://pubmed.ncbi.nlm.nih.gov/22171643

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

OX40 costimulation enhances interleukin-4 (IL-4) expression at priming and promotes the differentiation of naive human CD4(+) T cells into high IL-4-producing effectors

1 reference

https://pubmed.ncbi.nlm.nih.gov/22171643

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ox-40 ligand: a potent costimulatory molecule for sustaining primary CD4 T cell responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/22171643

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pulmonary veno-occlusive disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/22171643

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-6 causes mild pulmonary hypertension and augments hypoxia-induced pulmonary hypertension in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22171643

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical and immunoserological characteristics of mixed connective tissue disease associated with pulmonary arterial hypertension

1 reference

https://pubmed.ncbi.nlm.nih.gov/22171643

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/1471-2172-12-67

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

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PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

PubMed publication ID

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Europe PubMed Central

PubMed publication ID

31 July 2017

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