Branching out to gain control: how the pre-TCR is linked to multiple functions (Q34103329)

31 July 2017

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title

Branching out to gain control: how the pre-TCR is linked to multiple functions (English)

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Juan Carlos Zuniga-Pflucker

31 July 2017

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author name string

Kruisbeek AM

1

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31 July 2017

Haks MC

2

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31 July 2017

Carleton M

3

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31 July 2017

Michie AM

4

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31 July 2017

Zúñiga-Pflücker JC

5

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31 July 2017

Wiest DL

6

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31 July 2017

language of work or name

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1 December 2000

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31 July 2017

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31 July 2017

volume

21

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31 July 2017

issue

12

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31 July 2017

page(s)

637-644

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Cell-fate decisions in early T cell development: regulation by cytokine receptors and the pre-TCR

31 July 2017

cites work

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7 January 2021

In vivo roles of receptor tyrosine kinases and cytokine receptors in early thymocyte development

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7 January 2021

Pleiotropic changes controlled by the pre-T-cell receptor

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7 January 2021

In thymic selection, peptide diversity gives and takes away

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7 January 2021

Thymocyte selection: not by TCR alone.

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7 January 2021

Restoration of T cell development in RAG-2-deficient mice by functional TCR transgenes.

1 reference

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7 January 2021

T cell receptor beta chain gene rearrangement and selection during thymocyte development in adult mice

1 reference

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7 January 2021

Essential role of the pre-T cell receptor in allelic exclusion of the T cell receptor beta locus.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2800%2901744-8

7 January 2021

Redundant regulation of T cell differentiation and TCRalpha gene expression by the transcription factors LEF-1 and TCF-1

1 reference

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7 January 2021

A developmental switch from TCR delta enhancer to TCR alpha enhancer function during thymocyte maturation.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2800%2901744-8

7 January 2021

Pre-TCR signaling components trigger transcriptional activation of a rearranged TCR alpha gene locus and silencing of the pre-TCR alpha locus: implications for intrathymic differentiation.

1 reference

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7 January 2021

On the role of the pre-T cell receptor in alphabeta versus gammadelta T lineage commitment

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7 January 2021

Subunit composition of pre-T cell receptor complexes expressed by primary thymocytes: CD3 delta is physically associated but not functionally required.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2800%2901744-8

7 January 2021

A novel disulfide-linked heterodimer on pre-T cells consists of the T cell receptor beta chain and a 33 kd glycoprotein

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2800%2901744-8

7 January 2021

Analysis and expression of a cloned pre-T cell receptor gene

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2800%2901744-8

7 January 2021

Crucial role of the pre-T-cell receptor α gene in development of ap but not γδ T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2800%2901744-8

7 January 2021

CD3 delta deficiency arrests development of the alpha beta but not the gamma delta T cell lineage

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2800%2901744-8

7 January 2021

The CD3gamma chain is essential for development of both the TCRalphabeta and TCRgammadelta lineages

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2800%2901744-8

7 January 2021

T cell development in mice that lack the zeta chain of the T cell antigen receptor complex

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2800%2901744-8

7 January 2021

T cell development in mice lacking the CD3-zeta/eta gene.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2800%2901744-8

7 January 2021

Developmental and functional impairment of T cells in mice lacking CD3 zeta chains.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2800%2901744-8

7 January 2021

Mutations in T-cell antigen receptor genes alpha and beta block thymocyte development at different stages

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2800%2901744-8

7 January 2021

Specific requirement for CD3epsilon in T cell development.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2800%2901744-8

7 January 2021

Competitive displacement of pT alpha by TCR-alpha during TCR assembly prevents surface coexpression of pre-TCR and alpha beta TCR

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2800%2901744-8

7 January 2021

Thymocyte development in the absence of pre-T cell receptor extracellular immunoglobulin domains

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2800%2901744-8

7 January 2021

Exit of the pre-TCR from the ER/cis-Golgi is necessary for signaling differentiation, proliferation, and allelic exclusion in immature thymocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2800%2901744-8

7 January 2021

Restoration of thymopoiesis in pT alpha-/- mice by anti-CD3epsilon antibody treatment or with transgenes encoding activated Lck or tailless pT alpha.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2800%2901744-8

7 January 2021

The immunological synapse and the actin cytoskeleton: molecular hardware for T cell signaling.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2800%2901744-8

7 January 2021

Different initiation of pre-TCR and gammadeltaTCR signalling

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2800%2901744-8

7 January 2021

Profound block in thymocyte development in mice lacking p56lck

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2800%2901744-8

7 January 2021

An activated lck transgene promotes thymocyte development in RAG-1 mutant mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2800%2901744-8

7 January 2021

Pre-TCR signaling and inactivation of p53 induces crucial cell survival pathways in pre-T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2800%2901744-8

7 January 2021

alpha beta T cell development is abolished in mice lacking both Lck and Fyn protein tyrosine kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2800%2901744-8

7 January 2021

Fyn can partially substitute for Lck in T lymphocyte development

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2800%2901744-8

7 January 2021

Csk controls antigen receptor-mediated development and selection of T-lineage cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2800%2901744-8

7 January 2021

Normal B lymphocyte development but impaired T cell maturation in CD45-exon6 protein tyrosine phosphatase-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2800%2901744-8

7 January 2021

CD45-null transgenic mice reveal a positive regulatory role for CD45 in early thymocyte development, in the selection of CD4+CD8+ thymocytes, and B cell maturation

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2800%2901744-8

7 January 2021

The Syk and ZAP-70 SH2-containing tyrosine kinases are implicated in pre-T cell receptor signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2800%2901744-8

7 January 2021

Requirement for the leukocyte-specific adapter protein SLP-76 for normal T cell development

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2800%2901744-8

7 January 2021

Essential role of LAT in T cell development

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2800%2901744-8

7 January 2021

Impaired viability and profound block in thymocyte development in mice lacking the adaptor protein SLP-76.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2800%2901744-8

7 January 2021

Activated Ras signals differentiation and expansion of CD4+8+ thymocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2800%2901744-8

7 January 2021

Different functions of the GTPase Rho in prothymocytes and late pre-T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2800%2901744-8

7 January 2021

The GTPase rho controls a p53-dependent survival checkpoint during thymopoiesis

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2800%2901744-8

7 January 2021

Defective T-cell receptor signalling and positive selection of Vav-deficient CD4+ CD8+ thymocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2800%2901744-8

7 January 2021

A Requirement for the Rho-Family GTP Exchange Factor Vav in Positive and Negative Selection of Thymocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2800%2901744-8

7 January 2021

Defective antigen receptor-mediated proliferation of B and T cells in the absence of Vav.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2800%2901744-8

7 January 2021

Defective signalling through the T- and B-cell antigen receptors in lymphoid cells lacking the vav proto-oncogene

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2800%2901744-8

7 January 2021

Distinct signals mediate maturation and allelic exclusion in lymphocyte progenitors

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2800%2901744-8

7 January 2021

Immature thymocytes employ distinct signaling pathways for allelic exclusion versus differentiation and expansion

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2800%2901744-8

7 January 2021

Extracellular signal-regulated kinase (ERK) activation by the pre-T cell receptor in developing thymocytes in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2800%2901744-8

7 January 2021

Analysis of the role of MKK-4/Sek-1 in T cell development and apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2800%2901744-8

7 January 2021

JNK2 is required for efficient T-cell activation and apoptosis but not for normal lymphocyte development.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2800%2901744-8

7 January 2021

SEK1/MKK4 is required for maintenance of a normal peripheral lymphoid compartment but not for lymphocyte development

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2800%2901744-8

7 January 2021

Pre-T cell receptor (TCR) and TCR-controlled checkpoints in T cell differentiation are set by Ikaros

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2800%2901744-8

7 January 2021

Two distinct steps during thymocyte maturation from CD4-CD8- to CD4+CD8+ distinguished in the early growth response (Egr)-1 transgenic mice with a recombinase-activating gene-deficient background

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2800%2901744-8

7 January 2021

Generic signals and specific outcomes: signaling through Ca2+, calcineurin, and NF-AT

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2800%2901744-8

7 January 2021

p53 prevents maturation to the CD4+CD8+ stage of thymocyte differentiation in the absence of T cell receptor rearrangement.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2800%2901744-8

7 January 2021

p53 is required for both radiation-induced differentiation and rescue of V(D)J rearrangement in scid mouse thymocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2800%2901744-8

7 January 2021

Bcl-2 can rescue T lymphocyte development in interleukin-7 receptor-deficient mice but not in mutant rag-1-/- mice

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2800%2901744-8

7 January 2021

FADD/MORT1 regulates the pre-TCR checkpoint and can function as a tumour suppressor

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2800%2901744-8

7 January 2021

p56lck signals for regulating thymocyte development can be distinguished by their dependency on Rho function

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2800%2901744-8

7 January 2021

Allelic exclusion of the T cell receptor beta locus requires the SH2 domain-containing leukocyte protein (SLP)-76 adaptor protein

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2800%2901744-8

7 January 2021

Uncoupling of nonreceptor tyrosine kinases from PLC-gamma1 in an SLP-76-deficient T cell

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2800%2901744-8

7 January 2021

Phosphorylation of Tyr319 in ZAP-70 is required for T-cell antigen receptor-dependent phospholipase C-gamma1 and Ras activation

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2800%2901744-8

7 January 2021

PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2800%2901744-8

7 January 2021

Restoration of early thymocyte differentiation in T-cell receptor beta-chain-deficient mutant mice by transmembrane signaling through CD3 epsilon

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2800%2901744-8

7 January 2021

Regulation of thymocyte development through CD3: Functional dissociation between p56lck and CD3ζ in early thymic selection

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2800%2901744-8

7 January 2021

RAG-1-deficient mice have no mature B and T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2800%2901744-8

7 January 2021

RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2800%2901744-8

7 January 2021

CD3 components at the surface of pro-T cells can mediate pre-T cell developmentin vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2800%2901744-8

7 January 2021

CD3 epsilon-mediated signals rescue the development of CD4+CD8+ thymocytes in RAG-2-/- mice in the absence of TCR beta chain expression.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2800%2901744-8

7 January 2021

10.1016/S0167-5699(00)01744-8

Identifiers

DOI

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release_vjo5ro4lwvc2ncn4zza5udmmli

31 July 2017

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/vjo5ro4lwvc2ncn4zza5udmmli

24 November 2022

mapped directly with Wikidata item

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