Oxidative stress and autophagy in the regulation of lysosome-dependent neuron death. (Q34104922)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18764739%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

review article

1 reference

title

Oxidative stress and autophagy in the regulation of lysosome-dependent neuron death (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18764739%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

0 references

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18764739%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

author name string

Violetta N Pivtoraiko

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18764739%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

Sara L Stone

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18764739%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

John J Shacka

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18764739%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

publication date

1 March 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18764739%20AND%20SRC:MED&resulttype=core&format=json

Antioxidants & Redox Signaling

13 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18764739%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

volume

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18764739%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

page(s)

481-496

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18764739%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18764739%20AND%20SRC:MED&resulttype=core&format=json

Neurodegenerative lysosomal disorders: a continuum from development to late age.

13 January 2020

cites work

1 reference

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Alzheimer disease and the role of free radicals in the pathogenesis of the disease

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The autophagy-lysosomal degradation pathway: role in neurodegenerative disease and therapy.

28 July 2018

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Tumor necrosis factor-related apoptosis-inducing ligand activates a lysosomal pathway of apoptosis that is regulated by Bcl-2 proteins

28 July 2018

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28 July 2018

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28 July 2018

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Selective degradation of mitochondria by mitophagy

28 July 2018

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Cathepsin D-Bax death pathway in oxidative stressed neuroblastoma cells

28 July 2018

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Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4

28 July 2018

1 reference

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Autophagy, ageing and apoptosis: the role of oxidative stress and lysosomal iron

28 July 2018

1 reference

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Bioenergetics and the formation of mitochondrial reactive oxygen species.

28 July 2018

1 reference

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Antiamyloidogenic and neuroprotective functions of cathepsin B: implications for Alzheimer's disease

28 July 2018

1 reference

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New insights on the use of desipramine as an inhibitor for acid ceramidase

28 July 2018

1 reference

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Autophagy, bafilomycin and cell death: the "a-B-cs" of plecomacrolide-induced neuroprotection

28 July 2018

1 reference

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Cathepsin D deficiency is associated with a human neurodegenerative disorder

28 July 2018

1 reference

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Cathepsin D deficiency underlies congenital human neuronal ceroid-lipofuscinosis

28 July 2018

1 reference

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Release of iron from ferritin requires lysosomal activity

28 July 2018

1 reference

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Bafilomycin A1 inhibits chloroquine-induced death of cerebellar granule neurons

28 July 2018

1 reference

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Participation of autophagy in storage of lysosomes in neurons from mouse models of neuronal ceroid-lipofuscinoses (Batten disease).

28 July 2018

1 reference

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Cellular responses to protein accumulation involve autophagy and lysosomal enzyme activation

28 July 2018

1 reference

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Autophagy of amyloid beta-protein in differentiated neuroblastoma cells exposed to oxidative stress

28 July 2018

1 reference

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Metallothionein protects against oxidative stress-induced lysosomal destabilization

28 July 2018

1 reference

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Macroautophagy--a novel Beta-amyloid peptide-generating pathway activated in Alzheimer's disease

28 July 2018

1 reference

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Chloroquine-mediated radiosensitization is due to the destabilization of the lysosomal membrane and subsequent induction of cell death by necrosis.

28 July 2018

1 reference

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28 July 2018

The lysosome turns fifty

1 reference

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Disruptive effect of chloroquine on lysosomes in cultured rat hepatocytes

28 July 2018

1 reference

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Redundant cell death mechanisms as relics and backups

28 July 2018

1 reference

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Analysis of cytosolic and lysosomal pH in apoptotic cells by flow cytometry

28 July 2018

1 reference

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Membrane traffic to and from lysosomes

28 July 2018

1 reference

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Iron, brain ageing and neurodegenerative disorders

28 July 2018

1 reference

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Contribution of redox-active iron and copper to oxidative damage in Alzheimer disease

28 July 2018

1 reference

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Brain iron deposition and the free radical-mitochondrial theory of ageing

28 July 2018

1 reference

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28 July 2018

Lysosomes in cell death

1 reference

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The genetic spectrum of human neuronal ceroid-lipofuscinoses

28 July 2018

1 reference

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Current state of clinical and morphological features in human NCL.

28 July 2018

1 reference

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Ferriprotoporphyrin IX, phospholipids, and the antimalarial actions of quinoline drugs

28 July 2018

1 reference

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Cathepsin D links TNF-induced acid sphingomyelinase to Bid-mediated caspase-9 and -3 activation

28 July 2018

1 reference

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Examination of the mechanism(s) involved in doxorubicin-mediated iron accumulation in ferritin: studies using metabolic inhibitors, protein synthesis inhibitors, and lysosomotropic agents

28 July 2018

1 reference

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Lysosomes and brain aging in mammals

28 July 2018

1 reference

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Selective disruption of lysosomes in HeLa cells triggers apoptosis mediated by cleavage of Bid by multiple papain-like lysosomal cathepsins

28 July 2018

1 reference

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Mitochondrial membrane permeabilization is a critical step of lysosome-initiated apoptosis induced by hydroxychloroquine.

28 July 2018

1 reference

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Lysosomal activation is a compensatory response against protein accumulation and associated synaptopathogenesis--an approach for slowing Alzheimer disease?

28 July 2018

1 reference

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At the acidic edge: emerging functions for lysosomal membrane proteins

28 July 2018

1 reference

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Oxidative stress in brain aging. Implications for therapeutics of neurodegenerative diseases

28 July 2018

1 reference

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Lipofuscin: mechanisms of age-related accumulation and influence on cell function

28 July 2018

1 reference

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Bcl-2 phosphorylation is required for inhibition of oxidative stress-induced lysosomal leak and ensuing apoptosis

28 July 2018

1 reference

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Delayed oxidant-induced cell death involves activation of phospholipase A2.

28 July 2018

1 reference

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Zinc resistance impairs sensitivity to oxidative stress in HeLa cells: protection through metallothioneins expression

28 July 2018

1 reference

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Chloroquine-induced neuronal cell death is p53 and Bcl-2 family-dependent but caspase-independent

28 July 2018

1 reference

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Autophagic cell death and its execution by lysosomal cathepsins

28 July 2018

1 reference

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Caspases, apoptosis, and Alzheimer disease: causation, correlation, and confusion

28 July 2018

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Apoptosis induced by exposure to a low steady-state concentration of H2O2 is a consequence of lysosomal rupture

28 July 2018

1 reference

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Lysosomal membrane damage in soluble Abeta-mediated cell death in Alzheimer's disease

28 July 2018

1 reference

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Lysosomal protease pathways to apoptosis. Cleavage of bid, not pro-caspases, is the most likely route

28 July 2018

1 reference

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Cathepsin B contributes to TNF-alpha-mediated hepatocyte apoptosis by promoting mitochondrial release of cytochrome c

28 July 2018

1 reference

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Endocytic pathway abnormalities precede amyloid beta deposition in sporadic Alzheimer's disease and Down syndrome: differential effects of APOE genotype and presenilin mutations

28 July 2018

1 reference

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A mutation in the ovine cathepsin D gene causes a congenital lysosomal storage disease with profound neurodegeneration

28 July 2018

1 reference

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Induction of cell death by the lysosomotropic detergent MSDH.

28 July 2018

1 reference

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Ceroid/lipofuscin-loaded human fibroblasts show increased susceptibility to oxidative stress

28 July 2018

1 reference

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Postictal blockade of ischemic hippocampal neuronal death in primates using selective cathepsin inhibitors

28 July 2018

1 reference

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Ceroid/lipofuscin formation in cultured human fibroblasts: the role of oxidative stress and lysosomal proteolysis

28 July 2018

1 reference

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Iron in cytosolic ferritin can be recycled through lysosomal degradation in human fibroblasts

28 July 2018

1 reference

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Effect of chloroquine and leupeptin on intracellular accumulation of amyloid-beta (A beta) 1-42 peptide in a murine N9 microglial cell line

28 July 2018

1 reference

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Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

28 July 2018

1 reference

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Structural characterization and immunochemical detection of a fluorophore derived from 4-hydroxy-2-nonenal and lysine

28 July 2018

1 reference

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Lipofuscin: mechanisms of formation and increase with age.

28 July 2018

1 reference

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Lysosomotropic agents ameliorate macrophage dysfunction following the phagocytosis of IgG-coated erythrocytes: a role for lipid peroxidation

28 July 2018

1 reference

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Increased neuronal endocytosis and protease delivery to early endosomes in sporadic Alzheimer's disease: neuropathologic evidence for a mechanism of increased beta-amyloidogenesis.

28 July 2018

1 reference

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Chloroquine administration in mice increases beta-amyloid immunoreactivity and attenuates kainate-induced blood-brain barrier dysfunction

28 July 2018

1 reference

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Follow-up study of subunit c of mitochondrial ATP synthase (SCMAS) in Batten disease and in unrelated lysosomal disorders.

28 July 2018

1 reference

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Cathepsin D displays in vitro beta-secretase-like specificity.

28 July 2018

1 reference

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The autophagic and endocytic pathways converge at the nascent autophagic vacuoles

28 July 2018

1 reference

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Amyloidogenic processing of human amyloid precursor protein in hippocampal neurons devoid of cathepsin D.

28 July 2018

1 reference

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Inhibition of adenine nucleotide translocator by lipid peroxidation products

28 July 2018

1 reference

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Cellular injury induced by oxidative stress is mediated through lysosomal damage.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

Inactivation of glucose-6-phosphate dehydrogenase by 4-hydroxy-2-nonenal. Selective modification of an active-site lysine

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

Hydrogen peroxide mediates amyloid beta protein toxicity

28 July 2018

1 reference

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Lysosomal abnormalities in degenerating neurons link neuronal compromise to senile plaque development in Alzheimer disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

Inactivation of lysosomal proteases by oxidized low density lipoprotein is partially responsible for its poor degradation by mouse peritoneal macrophages

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

Inhibition of lysosomal acid sphingomyelinase by agents which reverse multidrug resistance

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

Mice deficient for the lysosomal proteinase cathepsin D exhibit progressive atrophy of the intestinal mucosa and profound destruction of lymphoid cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

Biosynthesis and processing of lysosomal cathepsin D in primary cultures of rat hepatocytes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

Bcl-x and Bcl-2 inhibit TNF and Fas-induced apoptosis and activation of phospholipase A2 in breast carcinoma cells.

28 July 2018

1 reference

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Cytoplasmic vacuolation of mouse peritoneal macrophages and the uptake into lysosomes of weakly basic substances

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

Chloroquine inhibits lysosomal enzyme pinocytosis and enhances lysosomal enzyme secretion by impairing receptor recycling

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

Effects of chloroquine on lysosomal enzymes, NADPH-induced lipid peroxidation, and antioxidant enzymes of rat retina

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

Inhibitors of lysosomal enzymes: accumulation of lipofuscin-like dense bodies in the brain

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

Effect of chloroquine on the stability of rat kidney lysosomes in vivo and in vitro

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

Protein degradation in cultured cells. II. The uptake of chloroquine by rat fibroblasts and the inhibition of cellular protein degradation and cathepsin B1.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

Commentary. Lysosomotropic agents

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

Histochemical indications for lysosomal localization of heavy metals in normal rat brain and liver.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

Lysosomal origin of the ferric iron required for cell killing by hydrogen peroxide

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

Responses of cultured cardiac myocytes to lysosomotropic compounds and methylated amino acids

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

A ferriprotoporphyrin IX-chloroquine complex promotes membrane phospholipid peroxidation. A possible mechanism for antimalarial action

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

Biosynthesis of lysosomal cathepsins B and H in cultured rat hepatocytes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

Bafilomycins: a class of inhibitors of membrane ATPases from microorganisms, animal cells, and plant cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

Effect of ambient oxygen concentration on lipofuscin accumulation in cultured rat heart myocytes--a novel in vitro model of lipofuscinogenesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

Association of the precursor of cathepsin D with coated membranes. Kinetics and carbohydrate processing

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

A study of the mechanisms of chloroquine retinopathy. I. Chloroquine effect on lipid peroxidation of retina

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

Lysosomal movements during heterophagy and autophagy: with special reference to nematolysosome and wrapping lysosome

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

Effects of cysteine protease inhibitors on rabbit cathepsin D maturation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

Lipofuscin-like substances accumulate rapidly in brain, retina and internal organs with cysteine protease inhibition

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

Lipofuscin and ceroid formation: the cellular recycling system

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

Lysosomal proteinase antigens are prominently localized within senile plaques of Alzheimer's disease: evidence for a neuronal origin.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

Lysosomal storage diseases

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

Lysosomal hydrolases of different classes are abnormally distributed in brains of patients with Alzheimer disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

Enzymatically active lysosomal proteases are associated with amyloid deposits in Alzheimer brain

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

A novel hypothesis of lipofuscinogenesis and cellular aging based on interactions between oxidative stress and autophagocytosis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

Proteases in cellular slime mold development: evidence for their involvement

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

Fluorescence probe measurement of the intralysosomal pH in living cells and the perturbation of pH by various agents

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

Zinc and 4-hydroxy-2-nonenal mediate lysosomal membrane permeabilization induced by H2O2 in cultured hippocampal neurons.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

Cell cycle-dependent induction of autophagy, mitophagy and reticulophagy

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

Zaprinast inhibits hydrogen peroxide-induced lysosomal destabilization and cell death in astrocytes.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

Involvement of lysosomal storage-induced p38 MAP kinase activation in the overproduction of nitric oxide by microglia in cathepsin D-deficient mice.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

28 October 2018

How shall I eat thee?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

ER-phagy: selective autophagy of the endoplasmic reticulum.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

Cathepsin D deficiency induces persistent neurodegeneration in the absence of Bax-dependent apoptosis.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

Altered regulation of phosphatidylinositol 3-kinase signaling in cathepsin D-deficient brain.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

Hypochlorous acid induces apoptosis of cultured cortical neurons through activation of calpains and rupture of lysosomes.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

Ceramide is the key mediator of oxidative stress-induced apoptosis in retinal photoreceptor cells.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

Intralysosomal iron chelation protects against oxidative stress-induced cellular damage.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

Different conformations of amyloid beta induce neurotoxicity by distinct mechanisms in human cortical neurons.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

The lysosomal-mitochondrial axis theory of postmitotic aging and cell death

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

Cytosolic acidification and lysosomal alkalinization during TNF-alpha induced apoptosis in U937 cells.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

Two distinct signaling pathways regulate peroxynitrite-induced apoptosis in PC12 cells

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

A mutation in the cathepsin D gene (CTSD) in American Bulldogs with neuronal ceroid lipofuscinosis

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

Extensive involvement of autophagy in Alzheimer disease: an immuno-electron microscopy study.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

Role of the autophagic-lysosomal system on low potassium-induced apoptosis in cultured cerebellar granule cells.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

Lysosomal enzymes promote mitochondrial oxidant production, cytochrome c release and apoptosis.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

Multiple signaling events in amyloid beta-induced, oxidative stress-dependent neuronal apoptosis

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

Cathepsin D triggers Bax activation, resulting in selective apoptosis-inducing factor (AIF) relocation in T lymphocytes entering the early commitment phase to apoptosis

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

Intralysosomal iron: a major determinant of oxidant-induced cell death

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

Microinjection of cathepsin d induces caspase-dependent apoptosis in fibroblasts

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

Inhibition of RPE lysosomal and antioxidant activity by the age pigment lipofuscin.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

Sphingosine-induced apoptosis is dependent on lysosomal proteases

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

Involvement of nitric oxide released from microglia-macrophages in pathological changes of cathepsin D-deficient mice.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

The lysosomal protease cathepsin D mediates apoptosis induced by oxidative stress.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

Methylmercury and H(2)O(2) provoke lysosomal damage in human astrocytoma D384 cells followed by apoptosis

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

A "protease activation cascade" in the pathogenesis of Alzheimer's disease.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

Up-regulation of the lysosomal system in experimental models of neuronal injury: implications for Alzheimer's disease.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

Cathepsin D deficiency induces lysosomal storage with ceroid lipofuscin in mouse CNS neurons

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

Amyloid beta-induced neuronal death is bax-dependent but caspase-independent.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

Mitochondrio-nuclear translocation of AIF in apoptosis and necrosis

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

Induction of human endothelial cell apoptosis requires both heat shock and oxidative stress responses

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

Lipofuscin accumulation and ageing of fibroblasts.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

Properties of the endosomal-lysosomal system in the human central nervous system: disturbances mark most neurons in populations at risk to degenerate in Alzheimer's disease.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

Susceptibility of glucose-6-phosphate dehydrogenase modified by 4-hydroxy-2-nonenal and metal-catalyzed oxidation to proteolysis by the multicatalytic protease.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

Chloroquine accumulation and alterations of proteolysis and pinocytosis in the rat conceptus in vitro

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

Gene expression and cellular content of cathepsin D in Alzheimer's disease brain: evidence for early up-regulation of the endosomal-lysosomal system.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

Autophagic degradation of protein generates a pool of ferric iron required for the killing of cultured hepatocytes by an oxidative stress

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933567

Structural and physical changes in lysosomes from isolated rat hepatocytes treated with methylamine

28 October 2018

1 reference

12 December 2020

Influence of oxygen tension, pro-oxidants and antioxidants on the formation of lipid peroxidation products (lipofuscin) in individual cultivated human glial cells

1 reference

12 December 2020

Prelysosomal convergence of autophagic and endocytic pathways

1 reference

12 December 2020

Ferritin iron kinetics and protein turnover in K562 cells

1 reference

12 December 2020

The Aβ Peptide of Alzheimer's Disease Directly Produces Hydrogen Peroxide through Metal Ion Reduction†

1 reference

12 December 2020

Kinetics of the pH-induced inactivation of human cathepsin L

1 reference

12 December 2020

Covalent attachment of 4-hydroxynonenal to glyceraldehyde-3-phosphate dehydrogenase. A possible involvement of intra- and intermolecular cross-linking reaction

1 reference

12 December 2020

Modification of glucose-6-phosphate dehydrogenase by 4-hydroxy-2-nonenal. Formation of cross-linked protein that inhibits the multicatalytic protease

1 reference

12 December 2020

Phagocytosis and degradation of rat liver mitochondria by cultivated human glial cells

1 reference

12 December 2020

Effects of lysosomotropic monoamines, diamines, amino alcohols, and other amino compounds on protein degradation and protein synthesis in isolated rat hepatocytes

1 reference

12 December 2020

1 reference

12 December 2020

Chemical characterization of a protein-4-hydroxy-2-nonenal cross-link: immunochemical detection in mitochondria exposed to oxidative stress

1 reference

12 December 2020

4-hydroxynonenal inhibits Na(+)-K(+)-ATPase

1 reference

12 December 2020

Chaperone-Mediated Autophagy

1 reference

12 December 2020

Microautophagy in the yeast Saccharomyces cerevisiae

1 reference

12 December 2020

Identifiers

DOI

10.1089/ARS.2008.2263

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18764739%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18764739%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

1 reference