Modifications of glycans: biological significance and therapeutic opportunities (Q34111293)

31 July 2017

title

Modifications of glycans: biological significance and therapeutic opportunities (English)

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31 July 2017

Saddam M Muthana

1

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31 July 2017

Christopher T Campbell

series ordinal

2

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31 July 2017

Jeffrey C Gildersleeve

series ordinal

3

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31 July 2017

publication date

11 January 2012

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31 July 2017

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31 July 2017

volume

7

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31 July 2017

issue

1

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31 July 2017

page(s)

31-43

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The proteoglycan bikunin has a defined sequence

31 July 2017

cites work

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5 July 2018

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5 July 2018

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5 July 2018

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Direct detection of HSulf-1 and HSulf-2 activities on extracellular heparan sulfate and their inhibition by PI-88

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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The role and metabolism of sulfatide in the nervous system

5 July 2018

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Structural characterization of the primary O-antigenic polysaccharide of the Rhizobium leguminosarum 3841 lipopolysaccharide and identification of a new 3-acetimidoylamino-3-deoxyhexuronic acid glycosyl component: a unique O-methylated glycan of uni

5 July 2018

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5 July 2018

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5 July 2018

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Decreased expression of human D-glucuronyl C5-epimerase in breast cancer.

5 July 2018

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5 July 2018

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O-methylated glycans from Toxocara are specific targets for antibody binding in human and animal infections

5 July 2018

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Influence of wall teichoic acid on lysozyme resistance in Staphylococcus aureus.

5 July 2018

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Sulfation patterns of glycosaminoglycans encode molecular recognition and activity

5 July 2018

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Identification of phosphorylation sites in N-linked glycans by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry

5 July 2018

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Glycomics approach to structure-function relationships of glycosaminoglycans

5 July 2018

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5 July 2018

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Role of an alginate lyase for alginate transport in mucoid Pseudomonas aeruginosa

5 July 2018

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5 July 2018

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Glycan foraging in vivo by an intestine-adapted bacterial symbiont

5 July 2018

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5 July 2018

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5 July 2018

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Biological roles of sulfoglycolipids and pathophysiology of their deficiency.

5 July 2018

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Discovery and characterization of sialic acid O-acetylation in group B Streptococcus

5 July 2018

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Neutral N-glycans of the gastropod Arion lusitanicus

5 July 2018

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A continuum of anionic charge: structures and functions of D-alanyl-teichoic acids in gram-positive bacteria

5 July 2018

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Toxocariasis: Clinical Aspects, Epidemiology, Medical Ecology, and Molecular Aspects

5 July 2018

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Methylation-associated silencing of heparan sulfate D-glucosaminyl 3-O-sulfotransferase-2 (3-OST-2) in human breast, colon, lung and pancreatic cancers

5 July 2018

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O-acetylation of GD3: an enigmatic modification regulating apoptosis?

5 July 2018

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Taking toll: lipid A mimetics as adjuvants and immunomodulators

5 July 2018

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Gangliosides with O-acetylated sialic acids in tumors of neuroectodermal origin

5 July 2018

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Mice deficient for the HNK-1 sulfotransferase show alterations in synaptic efficacy and spatial learning and memory

5 July 2018

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Mutant analysis and cellular localization of the AlgI, AlgJ, and AlgF proteins required for O acetylation of alginate in Pseudomonas aeruginosa

5 July 2018

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Paranodal junction formation and spermatogenesis require sulfoglycolipids

5 July 2018

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Chemical diversity in the sialic acids and related alpha-keto acids: an evolutionary perspective.

5 July 2018

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Carbohydrate-modifying sulfotransferases: structure, function, and pathophysiology

5 July 2018

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Biosynthesis of the arabinogalactan-peptidoglycan complex of Mycobacterium tuberculosis

5 July 2018

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Pectin methylesterases: cell wall enzymes with important roles in plant physiology

5 July 2018

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Regulation of Wnt signaling and embryo patterning by an extracellular sulfatase

5 July 2018

1 reference

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Regeneration of CNS axons back to their target following treatment of adult rat brain with chondroitinase ABC.

5 July 2018

1 reference

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Role of alginate O acetylation in resistance of mucoid Pseudomonas aeruginosa to opsonic phagocytosis

5 July 2018

1 reference

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Carbohydrate sulfotransferases: novel therapeutic targets for inflammation, viral infection and cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262866

Discovery of Carbohydrate Sulfotransferase Inhibitors from a Kinase-Directed Library We thank Sharon Long and Dave Keating for providing both the NodH sulfotransferase and APS Kinase during our preliminary experiments and Jack Kirsch for [...]

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262866

Molecular basis of variant pseudo-hurler polydystrophy (mucolipidosis IIIC)

5 July 2018

1 reference

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Glycoconjugates in Leishmania infectivity

5 July 2018

1 reference

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A novel, high endothelial venule-specific sulfotransferase expresses 6-sulfo sialyl Lewis(x), an L-selectin ligand displayed by CD34.

5 July 2018

1 reference

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Inhibition of L-selectin-mediated leukocyte rolling by synthetic glycoprotein mimics.

5 July 2018

1 reference

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Mycolic acids: structure, biosynthesis and physiological functions

5 July 2018

1 reference

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Human N-acetylglucosamine-6-O-sulfotransferase involved in the biosynthesis of 6-sulfo sialyl Lewis X: molecular cloning, chromosomal mapping, and expression in various organs and tumor cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262866

Sialic acids in molecular and cellular interactions

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262866

6'-sulfated sialyl Lewis x is a major capping group of GlyCAM-1.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262866

9-O-acetylated sialic acids have widespread but selective expression: analysis using a chimeric dual-function probe derived from influenza C hemagglutinin-esterase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262866

Influenza virus neuraminidase: structure, antibodies, and inhibitors

5 July 2018

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Structure of the capsular polysaccharide of Vibrio cholerae O139 synonym Bengal containing D-galactose 4,6-cyclophosphate.

5 July 2018

1 reference

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Identification by gas-liquid chromatography-mass spectrometry of 4-O-acetyl-9-O-lactyl-N-acetyl-neuraminic acid, a new sialic acid from horse submandibular gland

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262866

Phosphorylated oligosaccharides in lysosomal enzymes: identification of alpha-N-acetylglucosamine(1)phospho(6)mannose diester groups

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262866

Structure of a mycobacterial polysaccharide-fatty acyl-CoA complex: nuclear magnetic resonance studies

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262866

Demonstration of the enzymatic mechanisms of α-N-acetyl-d-glucosamine-1-phosphodiester N-acetylglucosaminidase (formerly called α-N-acetylglucosaminylphosphodiesterase) and lysosomal α-N-acetylglucosaminidase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262866

Immunological determinants of proteoglycans. Antibodies against the unsaturated oligosaccharide products of chondroitinase ABC-digested cartilage proteoglycans

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262866

Influenza C virus uses 9-O-acetyl-N-acetylneuraminic acid as a high affinity receptor determinant for attachment to cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262866

Distribution of mono-, di, and tri-O-acetylated sialic acids in normal and neoplastic colon.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262866

Trafficking of lysosomal enzymes.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262866

Alginate inhibition of the uptake of Pseudomonas aeruginosa by macrophages

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262866

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262866

O-acetylation and de-O-acetylation of sialic acids. Purification, characterization, and properties of a glycosylated rat liver esterase specific for 9-O-acetylated sialic acids.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262866

O-acetylation and de-O-acetylation of sialic acids. 7- and 9-o-acetylation of alpha 2,6-linked sialic acids on endogenous N-linked glycans in rat liver Golgi vesicles.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262866

Characterization of nematode glycoproteins: the major O-glycans of Toxocara excretory-secretory antigens are O-methylated trisaccharides

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262866

Defective acidification of intracellular organelles in cystic fibrosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262866

Structure and function of the mannose 6-phosphate/insulinlike growth factor II receptors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262866

Heterogeneity of the carbohydrate chains of sulfated bronchial glycoproteins isolated from a patient suffering from cystic fibrosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262866

How do nematodes transfer phosphorylcholine to carbohydrates?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262866

Omani-type spondyloepiphyseal dysplasia with cardiac involvement caused by a missense mutation in CHST3.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262866

Neutral N-glycan patterns of the gastropods Limax maximus, Cepaea hortensis, Planorbarius corneus, Arianta arbustorum and Achatina fulica.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262866

Inhibition of lipid A biosynthesis as the primary mechanism of CHIR-090 antibiotic activity in Escherichia coli

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262866

Increased hippocampal and cortical beta oscillations in mice deficient for the HNK-1 sulfotransferase

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262866

Discovery of a TNF-alpha antagonist using chondroitin sulfate microarrays

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262866

Structural elucidation of the extracellular and cell-wall teichoic acids of Staphylococcus aureus MN8m, a biofilm forming strain

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262866

N-acetylglucosamine-6-O-sulfotransferases 1 and 2 cooperatively control lymphocyte homing through L-selectin ligand biosynthesis in high endothelial venules

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262866

Interferon gamma promotes survival of lymphoblasts overexpressing 9-O-acetylated sialoglycoconjugates in childhood acute lymphoblastic leukaemia (ALL).

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262866

Pseudomonas aeruginosa alginate is refractory to Th1 immune response and impedes host immune clearance in a mouse model of acute lung infection.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262866

Substantial sulfatide deficiency and ceramide elevation in very early Alzheimer's disease: potential role in disease pathogenesis

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262866

Tumor necrosis factor alpha increases the expression of glycosyltransferases and sulfotransferases responsible for the biosynthesis of sialylated and/or sulfated Lewis x epitopes in the human bronchial mucosa

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262866

Characterization of the enzymatic 7-O-acetylation of sialic acids and evidence for enzymatic O-acetyl migration from C-7 to C-9 in bovine submandibular gland

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262866

The biosynthesis of 8-O-methylated sialic acids in the starfish Asterias rubens--isolation and characterisation of S-adenosyl-L-methionine:sialate-8-O-methyltransferase

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262866

Membrane lipids, selectively diminished in Alzheimer brains, suggest synapse loss as a primary event in early-onset form (type I) and demyelination in late-onset form (type II).

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262866

Identification of the sulfated monosaccharides of GlyCAM-1, an endothelial-derived ligand for L-selectin

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262866

Pyruvylated glycolipids from Mycobacterium smegmatis. Nature and location of the lipid components

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262866

Sialic acids in human gastric aspirates: detection of 9-O-lactyl- and 9-O-acetyl-N-acetylneuraminic acids and a decrease in total sialic acid concentration with age

28 October 2018

1 reference

12 December 2020

Proliferation of cultured fibroblasts is inhibited by L-iduronate-containing glycosaminoglycans

1 reference

12 December 2020

Low O-acetylation of sialyl-Le(x) contributes to its overexpression in colon carcinoma metastases

1 reference

12 December 2020

Characterisation of the enzymatic 4-O-acetylation of sialic acids in microsomes from equine submandibular glands

1 reference

12 December 2020

Sialic acids: fascinating sugars in higher animals and man

1 reference

12 December 2020

Monomer sequence and acetylation pattern in some bacterial alginates

1 reference

12 December 2020

N-GLYCOLYL-8-O-METHYLNEURAMINIC ACID, A NEW FORM OF SIALIC ACID IN THE STARFISH ASTERIAS FORBESI

1 reference

12 December 2020

Scavenging by alginate of free radicals released by macrophages

1 reference

12 December 2020

Structure-activity relationship of synthetic toll-like receptor 4 agonists

1 reference

12 December 2020

Enzymatic 4-O-acetylation of N-acetylneuraminic acid in guinea-pig liver

1 reference

12 December 2020

Mapping by monoclonal antibody detection of glycosaminoglycans in connective tissues

1 reference

12 December 2020

Sialylation and sulfation of the carbohydrate chains in respiratory mucins from a patient with cystic fibrosis

1 reference

12 December 2020

Characterization of N-glycolylneuraminic acid-containing gangliosides as tumor-associated Hanganutziu-Deicher antigen in human colon cancer

1 reference

12 December 2020

Effects of glycosaminoglycans on proliferation of epithelial and fibroblast human malignant mesothelioma cells: a structure-function relationship

1 reference

12 December 2020

Properties and partial purification of sialate-O-acetyltransferase from bovine submandibular glands

1 reference

12 December 2020

Role of teichoic acids in Staphylococcus aureus nasal colonization, a major risk factor in nosocomial infections

1 reference

12 December 2020

Characterization of the sialate-7(9)-O-acetyltransferase from the microsomes of human colonic mucosa

1 reference

12 December 2020

Spondyloepiphyseal dysplasia, Omani type: Further definition of the phenotype

1 reference

12 December 2020

Migration of O-acetyl groups in N,O-acetylneuraminic acids

1 reference

12 December 2020

Sialylation patterns of the mouse parotid secretory granules. Combined deacetylation, enzymatic degradation and lectin-gold binding

1 reference

12 December 2020

Isolation and properties of two sialate-O-acetylesterases from horse liver with 4- and 9-O-acetyl specificities

1 reference

12 December 2020

O-acetylation of sialic acids

1 reference

12 December 2020

Identifiers

DOI

10.1021/CB2004466

1 reference

31 July 2017

1 reference

31 July 2017

1 reference