Insights into the biologic and molecular abnormalities in adult acute lymphocytic leukemia (Q34123842)

31 July 2017

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title

Insights into the biologic and molecular abnormalities in adult acute lymphocytic leukemia (English)

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31 July 2017

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Faderl S

1

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PubMed ID

11147223

31 July 2017

Albitar M

series ordinal

2

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PubMed ID

11147223

31 July 2017

language of work or name

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1 December 2000

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Hematology / Oncology Clinics of North America

31 July 2017

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31 July 2017

14

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31 July 2017

6

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31 July 2017

1267-1288

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TEL-AML1 fusion in acute lymphoblastic leukaemia of adults

31 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

Outcome of treatment in children with Philadelphia chromosome-positive acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

Cell anchorage and the cytoskeleton as partners in growth factor dependent cell cycle progression

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

RAS inhibitors in hematologic cancers: biologic considerations and clinical applications

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

RAS and leukemia: from basic mechanisms to gene-directed therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

Emerging concepts in the Ras superfamily of GTP-binding proteins.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

Regulators and Effectors of ras Proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

Biology and clinical significance of the TEL/AML1 rearrangement

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

Surface antigen phenotype can predict TEL-AML1 rearrangement in childhood B-precursor ALL: a Pediatric Oncology Group study

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

Analysis of the BCR-ABL protein in Philadelphia chromosome-positive adult acute lymphocytic leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

The role of ATM in DNA damage responses and cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

Assignment of the gene for methylthioadenosine phosphorylase to human chromosome 9 by mouse-human somatic cell hybridization

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

Lymphoblastic leukemia with lymphomatous features associated with abnormalities of the short arm of chromosome 9

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

Deletions in the 13q14 locus in adult lymphoblastic leukemia: rate of incidence and relevance.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

Integrins and signal transduction pathways: the road taken

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

Induction of chronic myelogenous leukemia in mice by the P210bcr/abl gene of the Philadelphia chromosome

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

DNA damage-induced cell cycle checkpoints and DNA strand break repair in development and tumorigenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

Inactivation of cyclin-dependent kinase inhibitor genes and development of human acute leukemias

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

Critical study of prognostic factors in childhood acute lymphoblastic leukaemia: differences in outcome are poorly explained by the most significant prognostic variables. Fralle group. French Acute Lymphoblastic Leukaemia study group.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

Review of alterations of the cyclin-dependent kinase inhibitor INK4 family genes p15, p16, p18 and p19 in human leukemia-lymphoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

The biology of chronic myeloid leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

Outcome of Philadelphia chromosome-positive adult acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

Both TEL and AML-1 contribute repression domains to the t(12;21) fusion protein

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

PI3K: downstream AKTion blocks apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

Farnesyltransferase inhibitors: Ras research yields a potential cancer therapeutic

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

The potential of farnesyltransferase inhibitors as cancer chemotherapeutics

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

Hypermethylation of p16 and p15 genes and RB protein expression in acute leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

ATM gene deletion in patients with adult acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

Circulating soluble adhesion molecule levels in children with acute lymphoblastic leukaemia

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

Therapeutic intervention and signaling

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https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

Ultrastructural changes during adhesion and migration of pre-B lymphoid leukaemia cells within bone marrow stroma

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

TEL/AML1 fusion gene resulting from a cryptic t(12;21) is uncommon in adult patients with B-cell lineage ALL and CML lymphoblastic transformation.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

Integrins: versatility, modulation, and signaling in cell adhesion

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

Methylation of the multi tumor suppressor gene-2 (MTS2, CDKN1, p15INK4B) in childhood acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

Favorable prognosis associated with hyperdiploidy in children with acute lymphocytic leukemia correlates with extra chromosome 6. A Pediatric Oncology Group study

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

A cell cycle regulator potentially involved in genesis of many tumor types

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

Results of treatment with hyper-CVAD, a dose-intensive regimen, in adult acute lymphocytic leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

Alterations of the p53, p21, p16, p15 and RAS genes in childhood T-cell acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

Rapid ATM-dependent phosphorylation of MDM2 precedes p53 accumulation in response to DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

Oncogenic Ras activation of Raf/mitogen-activated protein kinase-independent pathways is sufficient to cause tumorigenic transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

A novel c-abl protein product in Philadelphia-positive acute lymphoblastic leukaemia

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

Low frequency of TEL/AML1 in adult acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

ATM: the product of the gene mutated in ataxia-telangiectasia

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

ATM: the protein encoded by the gene mutated in the radiosensitive syndrome ataxia-telangiectasia

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

Enhanced expression of p16ink4a is associated with a poor prognosis in childhood acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

Dichotomy of hyperdiploid acute lymphoblastic leukemia on the basis of the distribution of gained chromosomes

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

Selective homing of human leukemic B-cell precursors to specific lymphohematopoietic microenvironments in SCID mice: a role for the beta 1 integrin family surface adhesion molecules VLA-4 and VLA-5

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

Expression of intercellular adhesion molecule 1 (ICAM-1) in childhood acute lymphoblastic leukaemia: correlation with clinical features and outcome

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

The controlling role of ATM in homologous recombinational repair of DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

Molecular analysis of the 5q- chromosome

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

Rapid and reliable detection of N-ras mutations in acute lymphoblastic leukemia by melting curve analysis using LightCycler technology

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

Analysis of RAS oncogene mutations in human lymphoid malignancies

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

Hematopoiesis: how does it happen?

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

Analysis of TEL proteins in human leukemias

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

Acute lymphoblastic leukemia in children

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

Bcr-Abl oncoproteins bind directly to activators of the Ras signalling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

Low-molecular-weight GTP-binding proteins and leukocyte signal transduction.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

The vascular cell adhesion molecule (VCAM-1) is expressed on a subset of lymphoid and myeloid leukaemias

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

Phosphatidylinositol-3-OH kinase as a direct target of Ras

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

ATM: a mediator of multiple responses to genotoxic stress

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

TEL gene rearrangement in acute lymphoblastic leukemia: a new genetic marker with prognostic significance

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

Low frequency of TEL-AML1 in relapsed acute lymphoblastic leukemia supports a favorable prognosis for this genetic subgroup

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

Anchorage dependence, integrins, and apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

Mantle cell lymphoma is characterized by inactivation of the ATM gene

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

Cytogenetics adds independent prognostic information in adults with acute lymphoblastic leukaemia on MRC trial UKALL XA. MRC Adult Leukaemia Working Party.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

Prognostic implications of chromosomal findings in acute lymphoblastic leukaemia at diagnosis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

Role of the cyclin-dependent kinase 4 and 6 inhibitor gene family p15, p16, p18 and p19 in leukemia and lymphoma

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

Ph positive acute lymphoblastic leukemia in adults: molecular and clinical studies

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

Prognostic significance of TEL/AML1 fusion transcript in childhood B-precursor acute lymphoblastic leukemia.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

Homozygous deletions at 9p21 in childhood acute lymphoblastic leukemia detected by microsatellite analysis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

The ATM gene and susceptibility to childhood T-cell acute lymphoblastic leukaemia

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

Identification of three distinct regions of deletion on the long arm of chromosome 11 in childhood acute lymphoblastic leukemia.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

Serum soluble CD44 in pediatric patients with acute leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

Chromosomal localization of human leukocyte, fibroblast, and immune interferon genes by means of in situ hybridization

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

5q-, twenty-five years later: a synopsis

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

Biology of chronic myelogenous leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

Accumulation of methotrexate polyglutamates, ploidy and trisomies of both chromosomes 4 and 10 in lymphoblasts from children with B-progenitor cell acute lymphoblastic leukemia: a Pediatric Oncology Group Study

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

Mutational analysis of the N-ras gene in acute lymphoblastic leukemia: a study of 125 Japanese pediatric cases.

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

Incidence and clinical significance of CDKN2/MTS1/P16ink4A and MTS2/P15ink4B gene deletions in childhood acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS0889-8588%2805%2970186-6

7 January 2021

10.1016/S0889-8588(05)70186-6

Identifiers

DOI

1 reference

31 July 2017

1 reference

PubMed ID

11147223