A biomimetic polyketide-inspired approach to small-molecule ligand discovery (Q34136632)

31 July 2017

title

A biomimetic polyketide-inspired approach to small-molecule ligand discovery (English)

1 reference

31 July 2017

0 references

5

Thomas Kodadek

1 reference

31 July 2017

Claudio Aquino

1

1 reference

31 July 2017

Mohosin Sarkar

2

1 reference

31 July 2017

Michael J Chalmers

3

1 reference

31 July 2017

Kimberly Mendes

4

1 reference

31 July 2017

Glenn C Micalizio

6

1 reference

31 July 2017

publication date

20 November 2011

1 reference

31 July 2017

1 reference

31 July 2017

volume

4

1 reference

31 July 2017

issue

2

1 reference

31 July 2017

page(s)

99-104

1 reference

1,3-allylic strain as a strategic diversification element for constructing libraries of substituted 2-arylpiperidines.

31 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266625

Identification of candidate IgG biomarkers for Alzheimer's disease via combinatorial library screening

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266625

Small molecules of different origins have distinct distributions of structural complexity that correlate with protein-binding profiles

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266625

Peptide nucleic acids (PNA) in chemical biology and drug discovery

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266625

Awakening guardian angels: drugging the p53 pathway

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266625

The first 30 years of p53: growing ever more complex

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266625

Allylic and allenic halide synthesis via NbCl(5)- and NbBr(5)-mediated alkoxide rearrangements

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266625

Peptoids as potential therapeutics.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266625

PRIMA-1 reactivates mutant p53 by covalent binding to the core domain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266625

Skeletally diverse small molecules using a build/couple/pair strategy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266625

Synthesis of natural product inspired compound collections

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266625

Revisiting the modularity of modular polyketide synthases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266625

Synthesis of natural-product-like molecules with over eighty distinct scaffolds

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266625

Exploring beta-sheet structure and interactions with chemical model systems

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266625

Targeted rescue of a destabilized mutant of p53 by an in silico screened drug

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266625

Foldamers with heterogeneous backbones

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266625

Beta-peptidic peptidomimetics

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266625

Beta-hairpin peptidomimetics: design, structures and biological activities

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266625

A peptoid "antibody surrogate" that antagonizes VEGF receptor 2 activity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266625

Towards the optimal screening collection: a synthesis strategy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266625

Design and synthesis of a cell-permeable synthetic transcription factor mimic

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266625

The chemical versatility of natural-product assembly lines

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266625

Synthetic non-peptide mimetics of alpha-helices

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266625

Diversity-oriented synthesis: exploring the intersections between chemistry and biology

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266625

Peptide and protein sequence analysis by electron transfer dissociation mass spectrometry

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266625

Synthesis and Applications of Small Molecule Libraries

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266625

Diastereoselective magnesium halide-catalyzed anti-aldol reactions of chiral N-acyloxazolidinones

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266625

Molecular recognition of DNA by small molecules

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266625

The use of mRNA display to select high-affinity protein-binding peptides

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266625

Morpholino antisense oligomers: the case for an RNase H-independent structural type

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266625

Antagonists of protein-protein interactions.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266625

Target-oriented and diversity-oriented organic synthesis in drug discovery

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266625

Encoding strategies in combinatorial chemistry

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266625

General method for the rapid solid-phase synthesis of large numbers of peptides: specificity of antigen-antibody interaction at the level of individual amino acids

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266625

Peptoids: a modular approach to drug discovery.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3266625

Shape-programmable macromolecules

5 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.1200

Efficient method for the preparation of peptoids [oligo(N-substituted glycines)] by submonomer solid-phase synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.1200

Gold(I)-catalyzed coupling reactions for the synthesis of diverse small molecules using the build/couple/pair strategy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.1200

Alpha-aminoxy acids: new possibilities from foldamers to anion receptors and channels

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22270625

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

An Oligomer-Based Approach to Skeletal Diversity in Small-Molecule Synthesis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22270625

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Foldamers: A Manifesto

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.1200

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NCHEM.1200

1 reference

Dimensions Publication ID

31 July 2017

0 references

1 reference

31 July 2017

1 reference