The PPARα-FGF21 hormone axis contributes to metabolic regulation by the hepatic JNK signaling pathway (Q34143232)

31 July 2017

title

The PPARα-FGF21 hormone axis contributes to metabolic regulation by the hepatic JNK signaling pathway (English)

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31 July 2017

4

Guadalupe Sabio

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31 July 2017

5

Tamera Barrett

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31 July 2017

7

Jason K Kim

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31 July 2017

12

Roger J Davis

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31 July 2017

Santiago Vernia

1

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31 July 2017

Julie Cavanagh-Kyros

2

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31 July 2017

Luisa Garcia-Haro

3

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31 July 2017

Dae Young Jung

6

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31 July 2017

Jia Xu

8

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31 July 2017

Hennady P Shulha

9

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31 July 2017

Manuel Garber

10

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31 July 2017

Guangping Gao

11

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31 July 2017

publication date

17 July 2014

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31 July 2017

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31 July 2017

volume

20

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31 July 2017

issue

3

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31 July 2017

page(s)

512-525

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Regulation of steatohepatitis and PPARγ signaling by distinct AP-1 dimers

31 July 2017

cites work

1 reference

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Genome-wide map of nuclear protein degradation shows NCoR1 turnover as a key to mitochondrial gene regulation

5 July 2018

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Diet-induced obesity mediated by the JNK/DIO2 signal transduction pathway

5 July 2018

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Role of the mixed-lineage protein kinase pathway in the metabolic stress response to obesity

5 July 2018

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5 July 2018

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Distinct functions for RIP140 in development, inflammation, and metabolism

5 July 2018

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5 July 2018

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An FGF21-adiponectin-ceramide axis controls energy expenditure and insulin action in mice

5 July 2018

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5 July 2018

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JNK expression by macrophages promotes obesity-induced insulin resistance and inflammation

5 July 2018

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5 July 2018

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Stress-induced phosphorylation and proteasomal degradation of mitofusin 2 facilitates mitochondrial fragmentation and apoptosis.

5 July 2018

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Fibroblast growth factor-21 regulates PPARγ activity and the antidiabetic actions of thiazolidinediones.

5 July 2018

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FGF21 regulates PGC-1α and browning of white adipose tissues in adaptive thermogenesis

5 July 2018

1 reference

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Endocrine fibroblast growth factors 15/19 and 21: from feast to famine

5 July 2018

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Discovery of Potent and Selective Covalent Inhibitors of JNK

5 July 2018

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Genome-wide profiling of liver X receptor, retinoid X receptor, and peroxisome proliferator-activated receptor α in mouse liver reveals extensive sharing of binding sites

5 July 2018

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NCoR1 is a conserved physiological modulator of muscle mass and oxidative function

5 July 2018

1 reference

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Adipocyte NCoR knockout decreases PPARγ phosphorylation and enhances PPARγ activity and insulin sensitivity

5 July 2018

1 reference

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Resistance to thyroid hormone is modulated in vivo by the nuclear receptor corepressor (NCOR1).

5 July 2018

1 reference

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cJun NH2-terminal kinase 1 (JNK1): roles in metabolic regulation of insulin resistance

5 July 2018

1 reference

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PPARalpha: energy combustion, hypolipidemia, inflammation and cancer

5 July 2018

1 reference

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Hypothalamic and pituitary c-Jun N-terminal kinase 1 signaling coordinately regulates glucose metabolism

5 July 2018

1 reference

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Deconstructing repression: evolving models of co-repressor action

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156535

Role of the hypothalamic-pituitary-thyroid axis in metabolic regulation by JNK1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156535

Irs1 serine 307 promotes insulin sensitivity in mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156535

Prevention of steatosis by hepatic JNK1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156535

Role of muscle c-Jun NH2-terminal kinase 1 in obesity-induced insulin resistance

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156535

Fibroblast growth factor 21-deficient mice demonstrate impaired adaptation to ketosis

5 July 2018

1 reference

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Acute glucose-lowering and insulin-sensitizing action of FGF21 in insulin-resistant mouse models--association with liver and adipose tissue effects

5 July 2018

1 reference

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FGF21 induces PGC-1alpha and regulates carbohydrate and fatty acid metabolism during the adaptive starvation response

5 July 2018

1 reference

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A stress signaling pathway in adipose tissue regulates hepatic insulin resistance

5 July 2018

1 reference

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The nuclear corepressor, NCoR, regulates thyroid hormone action in vivo

5 July 2018

1 reference

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Fibroblast growth factor 21 corrects obesity in mice

5 July 2018

1 reference

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Adipose fibroblast growth factor 21 is up-regulated by peroxisome proliferator-activated receptor gamma and altered metabolic states.

5 July 2018

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Identification of a domain within peroxisome proliferator-activated receptor gamma regulating expression of a group of genes containing fibroblast growth factor 21 that are selectively repressed by SIRT1 in adipocytes

5 July 2018

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Suppression of p53-dependent senescence by the JNK signal transduction pathway

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156535

The nuclear receptor cofactor, receptor-interacting protein 140, is required for the regulation of hepatic lipid and glucose metabolism by liver X receptor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156535

Metabolic stress signaling mediated by mixed-lineage kinases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156535

Hepatic fibroblast growth factor 21 is regulated by PPARalpha and is a key mediator of hepatic lipid metabolism in ketotic states

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156535

Endocrine regulation of the fasting response by PPARalpha-mediated induction of fibroblast growth factor 21

5 July 2018

1 reference

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Mechanisms linking obesity to insulin resistance and type 2 diabetes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156535

FGF-21 as a novel metabolic regulator

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156535

A nuclear receptor corepressor transcriptional checkpoint controlling activator protein 1-dependent gene networks required for macrophage activation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156535

PPARs and the complex journey to obesity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156535

A central role for JNK in obesity and insulin resistance

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156535

Transgenic targeting of a dominant negative corepressor to liver blocks basal repression by thyroid hormone receptor and increases cell proliferation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156535

Signal transduction by the JNK group of MAP kinases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156535

The c-Jun NH(2)-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser(307)

5 July 2018

1 reference

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Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic beta cell-specific gene knock-outs using Cre recombinase

5 July 2018

1 reference

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Selective interaction of JNK protein kinase isoforms with transcription factors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156535

Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor

5 July 2018

1 reference

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Acute effects in vivo of anti-insulin serum on rates of fatty acid synthesis and activities of acetyl-coenzyme A carboxylase and pyruvate dehydrogenase in liver and epididymal adipose tissue of fed rats

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156535

Adiponectin mediates the metabolic effects of FGF21 on glucose homeostasis and insulin sensitivity in mice

5 July 2018

1 reference

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Fibroblast growth factor 21 reverses hepatic steatosis, increases energy expenditure, and improves insulin sensitivity in diet-induced obese mice

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156535

FoxO1 regulates multiple metabolic pathways in the liver: effects on gluconeogenic, glycolytic, and lipogenic gene expression

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156535

Differential effects of interleukin-6 and -10 on skeletal muscle and liver insulin action in vivo

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4156535

The regulation of ketogenesis from octanoic acid. The role of the tricarboxylic acid cycle and fatty acid synthesis

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25043817

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CMET.2014.06.010

1 reference

31 July 2017

1 reference

31 July 2017

1 reference