Regulation of steatohepatitis and PPARγ signaling by distinct AP-1 dimers (Q33621757)

28 July 2017

title

Regulation of steatohepatitis and PPARγ signaling by distinct AP-1 dimers (English)

1 reference

28 July 2017

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5

Johan Auwerx

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Sebastian C Hasenfuss

Sebastian C Hasenfuss

1

0 references

Evan G Williams

Evan G Williams

4

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Martin K Thomsen

Martin K Thomsen

3

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Erwin F. Wagner

Erwin F Wagner

6

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Latifa Bakiri

2

Latifa Bakiri

1 reference

28 July 2017

publication date

1 January 2014

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28 July 2017

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28 July 2017

volume

19

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28 July 2017

issue

1

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28 July 2017

page(s)

84-95

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All-trans-retinoic acid ameliorates hepatic steatosis in mice by a novel transcriptional cascade.

28 July 2017

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Nuclear receptor PPARγ-regulated monoacylglycerol O-acyltransferase 1 (MGAT1) expression is responsible for the lipid accumulation in diet-induced hepatic steatosis

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Intracellular lipid accumulation in liver and muscle and the insulin resistance syndrome

21 June 2018

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The epidemiology of nonalcoholic fatty liver disease: a global perspective

21 June 2018

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Inhibition of ADRP prevents diet-induced insulin resistance

21 June 2018

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Lipid droplets: a classic organelle with new outfits

21 June 2018

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Fat and beyond: the diverse biology of PPARgamma

21 June 2018

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Cidea is associated with lipid droplets and insulin sensitivity in humans

21 June 2018

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Hepatic steatosis in leptin-deficient mice is promoted by the PPARgamma target gene Fsp27.

21 June 2018

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Liver-specific deletion of histone deacetylase 3 disrupts metabolic transcriptional networks

21 June 2018

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PPAR-gamma regulates osteoclastogenesis in mice

21 June 2018

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Deciphering AP-1 function in tumorigenesis: fra-ternizing on target promoters

21 June 2018

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Hepatocyte survival in acute hepatitis is due to c-Jun/AP-1-dependent expression of inducible nitric oxide synthase

21 June 2018

1 reference

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PPAR gamma 2 prevents lipotoxicity by controlling adipose tissue expandability and peripheral lipid metabolism

21 June 2018

1 reference

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PPARs and molecular mechanisms of transrepression

21 June 2018

1 reference

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Thematic review series: adipocyte biology. Adipose tissue function and plasticity orchestrate nutritional adaptation.

21 June 2018

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Protection against Western diet-induced obesity and hepatic steatosis in liver fatty acid-binding protein knockout mice

21 June 2018

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Protection against fatty liver but normal adipogenesis in mice lacking adipose differentiation-related protein

21 June 2018

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Steatosis and hepatocellular carcinoma risk.

21 June 2018

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AP-1 subunits: quarrel and harmony among siblings

21 June 2018

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21 June 2018

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Molecular mediators of hepatic steatosis and liver injury

21 June 2018

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A new set of BXD recombinant inbred lines from advanced intercross populations in mice

21 June 2018

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Adipose tissue expression of the lipid droplet-associating proteins S3-12 and perilipin is controlled by peroxisome proliferator-activated receptor-gamma

21 June 2018

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AP-1: a double-edged sword in tumorigenesis

21 June 2018

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Decreased Hepatic Triglyceride Accumulation and Altered Fatty Acid Uptake in Mice with Deletion of the Liver Fatty Acid-binding Protein Gene

21 June 2018

1 reference

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Exploration, normalization, and summaries of high density oligonucleotide array probe level data

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4023468

Liver-specific disruption of PPARgamma in leptin-deficient mice improves fatty liver but aggravates diabetic phenotypes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4023468

Liver tumor development. c-Jun antagonizes the proapoptotic activity of p53

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4023468

Promoter specificity and biological activity of tethered AP-1 dimers

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4023468

AP-1 as a regulator of cell life and death

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4023468

Impaired postnatal hepatocyte proliferation and liver regeneration in mice lacking c-jun in the liver

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4023468

Fra-1 replaces c-Fos-dependent functions in mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4023468

Targeted disruption of the murine junD gene results in multiple defects in male reproductive function

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4023468

Differential regulation of peroxisome proliferator activated receptor gamma1 (PPARgamma1) and PPARgamma2 messenger RNA expression in the early stages of adipogenesis.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4023468

Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4023468

c-Jun dimerizes with itself and with c-Fos, forming complexes of different DNA binding affinities

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4023468

Activation of protein kinase C decreases phosphorylation of c-Jun at sites that negatively regulate its DNA-binding activity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4023468

Activator Protein 1 transcription factor Fos-related antigen 1 (Fra-1) is dispensable for murine liver fibrosis, but modulates xenobiotic metabolism.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4023468

Imaging of neutral lipids by oil red O for analyzing the metabolic status in health and disease

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4023468

Liver cancer initiation is controlled by AP-1 through SIRT6-dependent inhibition of survivin.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4023468

Liver peroxisome proliferator-activated receptor gamma contributes to hepatic steatosis, triglyceride clearance, and regulation of body fat mass.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4023468

Insulin stimulates phosphorylation of c-Jun, c-Fos, and Fos-related proteins in cultured adipocytes.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4023468

Fosl1 is a transcriptional target of c-Fos during osteoclast differentiation

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4023468

Transcriptional activation of SHP by PPAR-gamma in liver

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24411941

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Role for PPARγ in obesity-induced hepatic steatosis as determined by hepatocyte- and macrophage-specific conditional knockouts

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24411941

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CMET.2013.11.018

1 reference

28 July 2017

1 reference

28 July 2017

1 reference