IL-6 in autoimmune disease and chronic inflammatory proliferative disease (Q34148654)

31 July 2017

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title

IL-6 in autoimmune disease and chronic inflammatory proliferative disease (English)

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31 July 2017

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1 reference

Katsuhiko Ishihara

1

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PubMed ID

12220549

31 July 2017

Toshio Hirano

series ordinal

2

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31 July 2017

1 August 2002

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Cytokine and Growth Factor Reviews

31 July 2017

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31 July 2017

13

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31 July 2017

4-5

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31 July 2017

357-368

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Complementary DNA for a novel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin

31 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Interleukin 6 and its receptor: ten years later

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

A novel family of growth factor receptors: a common binding domain in the growth hormone, prolactin, erythropoietin and IL-6 receptors, and the p75 IL-2 receptor beta-chain

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Haemopoietic receptors and helical cytokines

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Structural design and molecular evolution of a cytokine receptor superfamily

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Cytokine receptors and signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Cytokine signaling through nonreceptor protein tyrosine kinases

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

IL-6 cytokine family and signal transduction: a model of the cytokine system

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Signaling mechanisms through gp130: a model of the cytokine system.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Roles of STAT3 in mediating the cell growth, differentiation and survival signals relayed through the IL-6 family of cytokine receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Dissection of signaling cascades through gp130 in vivo: reciprocal roles for STAT3- and SHP2-mediated signals in immune responses.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Tyrosine 759 of the cytokine receptor gp130 is involved in Listeria monocytogenes susceptibility

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Molecular basis underlying functional pleiotropy of cytokines and growth factors

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Human B-cell differentiation factor defined by an anti-peptide antibody and its possible role in autoantibody production

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Excessive production of interleukin 6/B cell stimulatory factor-2 in rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Interleukin 6 is required for the development of collagen-induced arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Delayed onset and reduced severity of collagen-induced arthritis in interleukin-6-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Interleukin 6 plays a key role in the development of antigen-induced arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

IL-6-deficient mice resist myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Disparate T cell requirements of two subsets of lupus-specific autoantibodies in pristane-treated mice

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Mycobacteria and autoimmunity

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Serum immunoglobulin levels in patients with active pulmonary tuberculosis and patients with Klebsiella infection

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Pathologic conditions associated with plasma cell dyscrasias: a study of 806 cases

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Excess risk of lymphomas, leukemia and myeloma in patients with rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Slow bacterial infections or autoimmunity?

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Induction of Plasma-Cell Neoplasms in Strain BALB/c Mice with Mineral Oil and Mineral Oil Adjuvants

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Induction of Plasma Cell Tumours in BALB/c Mice with 2,6,10,14-Tetramethylpentadecane (Pristane)

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Induction of lupus-associated autoantibodies in BALB/c mice by intraperitoneal injection of pristane

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

A macrophage-derived factor required by plasmacytomas for survival and proliferation in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Interleukin 6 dependence of anti-DNA antibody production: evidence for two pathways of autoantibody formation in pristane-induced lupus

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Interleukin-6 (IL-6) and acute phase proteins in the disease course of patients with systemic lupus erythematosus

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Plasma concentration of IL-6 in systemic lupus erythematosus; an indicator of disease activity?

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Profiles of cytokines (TNF alpha and IL-6) and acute phase proteins (CRP and alpha 1AG) related to the disease course in patients with systemic lupus erythematosus

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Elevated levels of interleukin-6 in cerebrospinal fluid from patients with systemic lupus erythematosus and central nervous system involvement

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Autostimulatory effects of IL-6 on excessive B cell differentiation in patients with systemic lupus erythematosus: analysis of IL-6 production and IL-6R expression

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Receptors for B cell stimulatory factor 2. Quantitation, specificity, distribution, and regulation of their expression

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

In vitro regulation of B cell differentiation by interleukin-6 and soluble CD23 in systemic lupus erythematosus B cell subpopulations and antigen-induced normal B cells

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Age-associated increase in interleukin 6 in MRL/lpr mice

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Structure and evolution of mouse interleukin 6 gene

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Abnormal T cells from lpr mice down-regulate transcription of interferon-gamma and tumor necrosis factor-alpha in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Abnormal distribution of IL-6 receptor in aged MRL/lpr mice: elevated expression on B cells and absence on CD4+ cells

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Differential sensitivity to interleukins of CD5+ and CD5- anti-DNA antibody-producing B cells in murine lupus

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Interleukin 6 promotes murine lupus in NZB/NZW F1 mice

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

IL-6 receptor blockage inhibits the onset of autoimmune kidney disease in NZB/W F1 mice

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Macrophage depletion decreases IgG anti-DNA in cultures from (NZB · NZW)F1 spleen cells by eliminating the main source of IL-6

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Imbalanced cytokine production by macrophages from autoimmune-prone mice

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

The role of oil and agalactosyl IgG in the induction of arthritis in rodent models

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Hypogalactosylation of immunoglobulin G sugar chains and elevated serum interleukin 6 in Castleman's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Glycosylation of IgG, immune complexes and IgG subclasses in the MRL-lpr/lpr mouse model of rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Glycosylation changes of IgG associated with rheumatoid arthritis can activate complement via the mannose-binding protein

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

IgG1 plasmacytosis in interleukin 6 transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Dysregulated interleukin 6 expression produces a syndrome resembling Castleman's disease in mice.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Genetics of Susceptibility to Plasmacytoma Induction. I. BALB/cAnN (C), C57BL/6N (B6), C57BL/Ka (BK), (C × B6)F 1 , (C × BK) F 1 , and C × B Recombinant-Inbred Strains

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Generation of plasmacytomas with the chromosomal translocation t(12;15) in interleukin 6 transgenic mice.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Interleukin 6 (IL-6) and its receptor: their role in plasma cell neoplasias

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Interleukin 6 is essential for in vivo development of B lineage neoplasms

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Cytokine balance and lipid antigen presentation in the NOD mouse pancreas during development of insulitis

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Demonstration of a TH1 cytokine profile in the late phase of NOD insulitis

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Essential role for interferon-gamma and interleukin-6 in autoimmune insulin-dependent diabetes in NOD/Wehi mice

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

An update on cytokines in the pathogenesis of insulin-dependent diabetes mellitus

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

B cell specificity contributes to the outcome of diabetes in nonobese diabetic mice

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

A Reg family protein is overexpressed in islets from a patient with new-onset type 1 diabetes and acts as T-cell autoantigen in NOD mice

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

High circulating concentrations of interleukin-6 in active Crohn's disease but not ulcerative colitis

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Evidence for continuous stimulation of interleukin-6 production in Crohn's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Frequently relapsing Crohn's disease is characterized by persistent elevation in interleukin-6 and soluble interleukin-2 receptor serum levels during remission.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Significant increase of interleukin 6 production in blood mononuclear leukocytes obtained from patients with active inflammatory bowel disease

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Activation of Monocytes during Inflammatory Bowel Disease

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Colonic Mucosal Interleukin-6 in Inflammatory Bowel Disease

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Tumor necrosis factor-alpha, interleukin-1 beta, and interleukin-6 expression in inflammatory bowel disease

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Expression of interleukin-6 by intestinal enterocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Enhanced secretion of tumour necrosis factor-alpha, IL-6, and IL-1 beta by isolated lamina propria mononuclear cells from patients with ulcerative colitis and Crohn's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Blockade of interleukin 6 trans signaling suppresses T-cell resistanceagainst apoptosis in chronic intestinal inflammation: Evidence in Crohn diseaseand experimental colitis in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

CIS3/SOCS3/SSI3 plays a negative regulatory role in STAT3 activation and intestinal inflammation

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

IL-6-deficient mice are resistant to the induction of experimental autoimmune encephalomyelitis provoked by myelin oligodendrocyte glycoprotein

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

IL-6 plays a crucial role in the induction phase of myelin oligodendrocyte glucoprotein 35-55 induced experimental autoimmune encephalomyelitis.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

1 reference

7 January 2021

The immunopathology of joint inflammation in rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Revival of the autoantibody model in rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Pathogenesis of arthritis: recent research progress

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Anti-TNF alpha therapy of rheumatoid arthritis: what have we learned?

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Interleukin-6 in synovial fluid and serum of patients with rheumatoid arthritis and other inflammatory arthritides

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Interleukin-1 production by mononuclear cells from rheumatoid synovial effusions

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Correlation of serum interleukin-6 levels with joint involvement and thrombocytosis in systemic juvenile rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Enhanced production of interleukin-6 in mice with type II collagen-induced arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Synovium as a source of interleukin 6 in vitro. Contribution to local and systemic manifestations of arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Chemokines regulate IL-6 and IL-8 production by fibroblast-like synoviocytes from patients with rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Interleukin 6. A potential autocrine/paracrine factor in Paget's disease of bone

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Interleukin-6: an osteotropic factor?

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Involvement of IL-6, apart from its role in immunity, in mediating a chronic response during experimental arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Interleukin-6 gene -174g>c and -572g>c promoter polymorphisms are strong predictors of plasma interleukin-6 levels after coronary artery bypass surgery

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

The effect of novel polymorphisms in the interleukin-6 (IL-6) gene on IL-6 transcription and plasma IL-6 levels, and an association with systemic-onset juvenile chronic arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

A polymorphism in the promoter region of the gene for interleukin-6 is associated with susceptibility to type 1 diabetes mellitus

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Association of IL-6 gene alleles with systemic lupus erythematosus (SLE) and with elevated IL-6 expression

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

The polymorphism at position –174 of the IL-6 gene is not associated with inflammatory bowel disease

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Cooperative influence of genetic polymorphisms on interleukin 6 transcriptional regulation

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

High-resolution analysis of IL-6 minisatellite polymorphism in Sardinian multiple sclerosis: effect on course and onset of disease

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Is interleukin-6 important in inflammatory bowel disease?

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Induction of the cytokine signal regulator SOCS3/CIS3 as a therapeutic strategy for treating inflammatory arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Tissue-specific autoregulation of the stat3 gene and its role in interleukin-6-induced survival signals in T cells

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Activation-induced inhibition of interleukin 6-mediated T cell survival and signal transducer and activator of transcription 1 signaling

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

In vivo priming of T cells against cryptic determinants by dendritic cells exposed to interleukin 6 and native antigen.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

Impaired activity of thiol-dependent ATPases in rheumatoid mononuclear cell membranes

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6101%2802%2900027-8

7 January 2021

10.1016/S1359-6101(02)00027-8

Identifiers

DOI

1 reference

31 July 2017

1 reference

PubMed ID

12220549