5'-3'-UTR interactions regulate p53 mRNA translation and provide a target for modulating p53 induction after DNA damage (Q34164895)

31 July 2017

title

5'-3'-UTR interactions regulate p53 mRNA translation and provide a target for modulating p53 induction after DNA damage (English)

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31 July 2017

0 references

Jing Chen

1

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31 July 2017

Michael B Kastan

series ordinal

2

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31 July 2017

publication date

13 September 2010

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31 July 2017

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31 July 2017

volume

24

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31 July 2017

issue

19

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31 July 2017

page(s)

2146-2156

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TP53 mutations in human cancers: origins, consequences, and clinical use

31 July 2017

cites work

1 reference

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5 July 2018

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The first 30 years of p53: growing ever more complex

5 July 2018

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Regulation of translation initiation in eukaryotes: mechanisms and biological targets

5 July 2018

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Pifithrin-alpha protects against DNA damage-induced apoptosis downstream of mitochondria independent of p53.

5 July 2018

1 reference

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Mdm2 regulates p53 mRNA translation through inhibitory interactions with ribosomal protein L26

5 July 2018

1 reference

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Translation factors promote the formation of two states of the closed-loop mRNP.

5 July 2018

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5 July 2018

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5 July 2018

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Switching from repression to activation: microRNAs can up-regulate translation

5 July 2018

1 reference

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Wild-type p53: tumors can't stand it.

5 July 2018

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Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas

5 July 2018

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Restoration of p53 function leads to tumour regression in vivo

5 July 2018

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Modeling the therapeutic efficacy of p53 restoration in tumors

5 July 2018

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MIWI associates with translational machinery and PIWI-interacting RNAs (piRNAs) in regulating spermatogenesis

5 July 2018

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A novel class of small RNAs in mouse spermatogenic cells

5 July 2018

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End-to-end communication in the modulation of translation by mammalian RNA viruses

5 July 2018

1 reference

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Regulation of p53 translation and induction after DNA damage by ribosomal protein L26 and nucleolin

5 July 2018

1 reference

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The implications of structured 5' untranslated regions on translation and disease

5 July 2018

1 reference

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Cell-cycle checkpoints and cancer

5 July 2018

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The power of the 3' UTR: translational control and development

5 July 2018

1 reference

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RNA-binding protein HuR enhances p53 translation in response to ultraviolet light irradiation

5 July 2018

1 reference

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The role of p53 in determining sensitivity to radiotherapy

5 July 2018

1 reference

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The p53-Mdm2 module and the ubiquitin system.

5 July 2018

1 reference

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Base-pairing between untranslated regions facilitates translation of uncapped, nonpolyadenylated viral RNA.

5 July 2018

1 reference

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Cellular senescence: mitotic clock or culture shock?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947767

Regulation of p53 stability

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947767

A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947767

p53 is involved in but not required for ionizing radiation-induced caspase-3 activation and apoptosis in human lymphoblast cell lines.

5 July 2018

1 reference

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The complexity of p53 modulation: emerging patterns from divergent signals

5 July 2018

1 reference

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Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947767

Programmed cell death by hok/sok of plasmid R1: processing at the hok mRNA 3'-end triggers structural rearrangements that allow translation and antisense RNA binding

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947767

Participation of the human p53 3'UTR in translational repression and activation following gamma-irradiation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947767

Regulation of p53 stability by Mdm2

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947767

Mdm2 promotes the rapid degradation of p53

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947767

p53, the cellular gatekeeper for growth and division

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947767

Translational regulation by mRNA/protein interactions in eukaryotic cells: ferritin and beyond

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947767

Regulation of translation by specific protein/mRNA interactions

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947767

Messenger RNA degradation in eukaryotes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947767

Negative feedback regulation of wild-type p53 biosynthesis.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947767

Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947767

Translational repression of C. elegans p53 by GLD-1 regulates DNA damage-induced apoptosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947767

Regulation of protein synthesis by mRNA structure

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20837656

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Signaling to p53: breaking the MDM2-p53 circuit

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20837656

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Loss of atm radiosensitizes multiple p53 null tissues

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20837656

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1101/GAD.1968910

1 reference

31 July 2017

1 reference

31 July 2017

1 reference