Altered bone development and an increase in FGF-23 expression in Enpp1(-/-) mice (Q34168605)

31 July 2017

Altered bone development and an increase in FGF-23 expression in Enpp1(-/-) mice (English)

1 reference

31 July 2017

Dongxing Zhu

2

0 references

Rob J van 't Hof

object named as

Rob van 't Hof

4

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Colin Farquharson

object named as

Colin Farquharson

8

0 references

Vicky MacRae

object named as

Vicky Elisabeth MacRae

9

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author name string

Neil Charles Wallace Mackenzie

1

1 reference

31 July 2017

Elspeth M Milne

3

1 reference

31 July 2017

Aline Martin

5

1 reference

31 July 2017

Leigh Darryl Quarles

6

1 reference

31 July 2017

José Luis Millán

7

1 reference

31 July 2017

language of work or name

English

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publication date

16 February 2012

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31 July 2017

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31 July 2017

7

1 reference

31 July 2017

2

1 reference

31 July 2017

e32177

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Creative Commons Attribution 4.0 International

31 July 2017

start time

16 February 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3281127/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Ectonucleotide pyrophosphatase/phosphodiesterase-1 (ENPP1) protein regulates osteoblast differentiation

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Bone proteins PHEX and DMP1 regulate fibroblastic growth factor Fgf23 expression in osteocytes through a common pathway involving FGF receptor (FGFR) signaling.

5 July 2018

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PHOSPHO1 is essential for mechanically competent mineralization and the avoidance of spontaneous fractures

5 July 2018

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A Phe377del mutation in ANK leads to impaired osteoblastogenesis and osteoclastogenesis in a mouse model for craniometaphyseal dysplasia (CMD)

5 July 2018

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Insulin signaling in osteoblasts integrates bone remodeling and energy metabolism

5 July 2018

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Purinergic signalling and bone remodelling.

5 July 2018

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Loss-of-function ENPP1 mutations cause both generalized arterial calcification of infancy and autosomal-recessive hypophosphatemic rickets

5 July 2018

1 reference

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Autosomal-recessive hypophosphatemic rickets is associated with an inactivation mutation in the ENPP1 gene

5 July 2018

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Active creatine kinase is present in matrix vesicles isolated from femurs of chicken embryo: Implications for bone mineralization

5 July 2018

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Chondrocyte p21(WAF1/CIP1) expression is increased by dexamethasone but does not contribute to dexamethasone-induced growth retardation in vivo

5 July 2018

1 reference

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New variants in the Enpp1 and Ptpn6 genes cause low BMD, crystal-related arthropathy, and vascular calcification

5 July 2018

1 reference

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Autocrine ATP release coupled to extracellular pyrophosphate accumulation in vascular smooth muscle cells.

5 July 2018

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Endocrine functions of bone in mineral metabolism regulation.

5 July 2018

1 reference

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Genetic evidence of serum phosphate-independent functions of FGF-23 on bone

5 July 2018

1 reference

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Pathogenic role of Fgf23 in Dmp1-null mice.

5 July 2018

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Vascular calcification: pathobiology of a multifaceted disease

5 July 2018

1 reference

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Osteocalcin differentially regulates beta cell and adipocyte gene expression and affects the development of metabolic diseases in wild-type mice

5 July 2018

1 reference

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The parathyroid is a target organ for FGF23 in rats

5 July 2018

1 reference

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Pyrophosphate inhibits mineralization of osteoblast cultures by binding to mineral, up-regulating osteopontin, and inhibiting alkaline phosphatase activity

5 July 2018

1 reference

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Mechanisms of disease: Ectonucleotide pyrophosphatase phosphodiesterase 1 as a 'gatekeeper' of insulin receptors

5 July 2018

1 reference

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Regulation of fibroblast growth factor-23 signaling by klotho

5 July 2018

1 reference

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Sustained osteomalacia of long bones despite major improvement in other hypophosphatasia-related mineral deficits in tissue nonspecific alkaline phosphatase/nucleotide pyrophosphatase phosphodiesterase 1 double-deficient mice.

5 July 2018

1 reference

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Unique coexpression in osteoblasts of broadly expressed genes accounts for the spatial restriction of ECM mineralization to bone

5 July 2018

1 reference

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Increased hepatic levels of the insulin receptor inhibitor, PC-1/NPP1, induce insulin resistance and glucose intolerance.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281127

Inorganic pyrophosphate (PPI) in pathologic calcification of articular cartilage

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281127

Extracellular matrix mineralization is regulated locally; different roles of two gla-containing proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281127

Concerted regulation of inorganic pyrophosphate and osteopontin by akp2, enpp1, and ank: an integrated model of the pathogenesis of mineralization disorders

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281127

Mutations in ENPP1 are associated with 'idiopathic' infantile arterial calcification

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281127

Matrix vesicles and calcification

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281127

Tissue-nonspecific alkaline phosphatase and plasma cell membrane glycoprotein-1 are central antagonistic regulators of bone mineralization

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281127

PC-1 nucleoside triphosphate pyrophosphohydrolase deficiency in idiopathic infantile arterial calcification

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281127

5 July 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281127

5 July 2018

12 December 2020

Role of the mouse ank gene in control of tissue calcification and arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281127

Calcitonin simultaneously regulates both periosteal hyperostosis and trabecular osteopenia in the spinal hyperostotic mouse (twy/twy) in vivo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281127

Mutation in Npps in a mouse model of ossification of the posterior longitudinal ligament of the spine

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281127

Characteristics and mechanism of the ossification of posterior longitudinal ligament in the tip-toe walking Yoshimura (twy) mouse

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281127

Cytoskeletal changes in osteoclasts during the resorption cycle

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281127

Arthritis and ankylosis in twy mice with hereditary multiple osteochondral lesions: with special reference to calcium deposition.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281127

Calcitonin alters behaviour of isolated osteoclasts

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281127

Association of inorganic-pyrophosphatase activity with human alkaline-phosphatase preparations

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281127

Matrix vesicle biogenesis in vitro by rachitic and normal rat chondrocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281127

Different missense mutations at the tissue-nonspecific alkaline phosphatase gene locus in autosomal recessively inherited forms of mild and severe hypophosphatasia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281127

Studies on matrix vesicles isolated from chick epiphyseal cartilage Association of pyrophosphatase and ATPase activities with alkaline phosphatase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281127

Brain-type creatine kinase has a crucial role in osteoclast-mediated bone resorption

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281127

Elevated skeletal osteopontin levels contribute to the hypophosphatasia phenotype in Akp2(-/-) mice

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281127

Pathogenic role of Fgf23 in Hyp mice.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281127

Chondrogenesis mediated by PPi depletion promotes spontaneous aortic calcification in NPP1-/- mice

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281127

Human vascular smooth muscle cells undergo vesicle-mediated calcification in response to changes in extracellular calcium and phosphate concentrations: a potential mechanism for accelerated vascular calcification in ESRD.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281127

Linked deficiencies in extracellular PP(i) and osteopontin mediate pathologic calcification associated with defective PC-1 and ANK expression

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281127

The nucleoside triphosphate pyrophosphohydrolase isozyme PC-1 directly promotes cartilage calcification through chondrocyte apoptosis and increased calcium precipitation by mineralizing vesicles.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281127

Osteoblast tissue-nonspecific alkaline phosphatase antagonizes and regulates PC-1.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281127

Osteoclast ruffled border has distinct subdomains for secretion and degraded matrix uptake

28 October 2018

1 reference

12 December 2020

Can biological calcification occur in the presence of pyrophosphate?

1 reference

12 December 2020

Hereditary joint disorder in progressive ankylosis (ank/ank) mice I. association of calcium hydroxyapatite deposition with inflammatory arthropathy

1 reference

12 December 2020

Causal link between nucleotide pyrophosphohydrolase overactivity and increased intracellular inorganic pyrophosphate generation demonstrated by transfection of cultured fibroblasts and osteoblasts with plasma cell membrane glycoprotein-1. Relevance

1 reference

12 December 2020

Potential role of streptozotocin in enhancing ossification of the posterior longitudinal ligament of the cervical spine in the hereditary spinal hyperostotic mouse (twy/twy)

1 reference

12 December 2020

Porcine ecto-nucleotide pyrophosphatase/phosphodiesterase 1 (NPP1/CD203a): Cloning, transcription, expression, mapping, and identification of an NPP1/CD203a epitope for swine workshop cluster 9 (SWC9) monoclonal antibodies

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0032177

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DOI

1 reference

31 July 2017

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1 reference

31 July 2017

1 reference