Characterization of 3,4-methylenedioxymethamphetamine (MDMA) enantiomers in vitro and in the MPTP-lesioned primate: R-MDMA reduces severity of dyskinesia, whereas S-MDMA extends duration of ON-time. (Q34184343)

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English	Characterization of 3,4-methylenedioxymethamphetamine (MDMA) enantiomers in vitro and in the MPTP-lesioned primate: R-MDMA reduces severity of dyskinesia, whereas S-MDMA extends duration of ON-time.	scientific article

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Characterization of 3,4-methylenedioxymethamphetamine (MDMA) enantiomers in vitro and in the MPTP-lesioned primate: R-MDMA reduces severity of dyskinesia, whereas S-MDMA extends duration of ON-time (English)

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Tom H. Johnston

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Matthew J Piggott

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Jonathan M. Brotchie

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James B Koprich

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James B Koprich

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Gabriela Gutierrez-Reyes

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M Gabriela Reyes

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Philippe Huot

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Katie D Lewis

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Susan H Fox

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1 May 2011

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Journal of Neuroscience

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7190-7198

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31 January 2020

Organization of the basal ganglia: the importance of axonal collateralization

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Quetiapine attenuates levodopa-induced motor complications in rodent and primate parkinsonian models

1 reference

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12 December 2020

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Dopamine, but not norepinephrine or serotonin, reuptake inhibition reverses motor deficits in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated primates

1 reference

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12 December 2020

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Endogenous 5‐HT, released by MDMA through serotonin transporter‐ and secretory vesicle‐dependent mechanisms, reduces hippocampal excitatory synaptic transmission by preferential activation of 5‐HT1B receptors located on CA1 pyramidal neurons

1 reference

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12 December 2020

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3,4-Methylenedioxymethamphetamine (Ecstasy) Inhibits Dyskinesia Expression and Normalizes Motor Activity in 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Treated Primates

1 reference

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12 December 2020

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Clozapine improves dyskinesias in Parkinson disease: a double-blind, placebo-controlled study

1 reference

https://pubmed.ncbi.nlm.nih.gov/21562283

12 December 2020

based on heuristic

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Protein measurement with the Folin phenol reagent

1 reference

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12 December 2020

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Sydney Multicenter Study of Parkinson's disease: non-L-dopa-responsive problems dominate at 15 years

1 reference

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12 December 2020

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Topiramate reduces levodopa-induced dyskinesia in the MPTP-lesioned marmoset model of Parkinson's disease.

1 reference

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12 December 2020

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A randomized placebo-controlled trial of rasagiline in levodopa-treated patients with Parkinson disease and motor fluctuations: the PRESTO study

1 reference

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12 December 2020

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Serotonin 5-HT2A but not 5-HT2C receptor antagonism reduces hyperlocomotor activity induced in dopamine-depleted rats by striatal administration of the D1 agonist SKF 82958.

1 reference

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12 December 2020

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MDMA (Ecstasy) and human dopamine, norepinephrine, and serotonin transporters: implications for MDMA-induced neurotoxicity and treatment.

1 reference

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12 December 2020

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Serotonin 2A receptor antagonist treatment reduces dopamine D1 receptor-mediated rotational behavior but not L-DOPA-induced abnormal involuntary movements in the unilateral dopamine-depleted rat.

1 reference

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12 December 2020

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Histamine H3 receptor agonists reduce L-dopa-induced chorea, but not dystonia, in the MPTP-lesioned nonhuman primate model of Parkinson's disease

1 reference

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12 December 2020

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MDMA and fenfluramine reduce L-DOPA-induced dyskinesia via indirect 5-HT1A receptor stimulation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21562283

12 December 2020

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ACP-103, a 5-HT2A receptor inverse agonist

1 reference

https://pubmed.ncbi.nlm.nih.gov/21562283

12 December 2020

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WAY-100635 is a potent dopamine D4 receptor agonist

1 reference

https://pubmed.ncbi.nlm.nih.gov/21562283

12 December 2020

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Pharmacological characterization of psychosis-like behavior in the MPTP-lesioned nonhuman primate model of Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/21562283

12 December 2020

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Dopamine receptor agonists and levodopa and inducing psychosis-like behavior in the MPTP primate model of Parkinson disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21562283

12 December 2020

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Activation, internalization, and recycling of the serotonin 2A receptor by dopamine.

1 reference

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12 December 2020

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Randomized trial of the triple monoamine reuptake inhibitor NS 2330 (tesofensine) in early Parkinson's disease

1 reference

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12 December 2020

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New insights into the mechanism of action of amphetamines

1 reference

https://pubmed.ncbi.nlm.nih.gov/21562283

12 December 2020

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Dopamine released from 5-HT terminals is the cause of L-DOPA-induced dyskinesia in parkinsonian rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21562283

12 December 2020

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Dopamine dysregulation syndrome, addiction and behavioral changes in Parkinson's disease

1 reference

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12 December 2020

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The role of anxiety in the development of levodopa-induced dyskinesias in an animal model of Parkinson's disease, and the effect of chronic treatment with the selective serotonin reuptake inhibitor citalopram.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21562283

12 December 2020

based on heuristic

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A 5-HT2A receptor inverse agonist, ACP-103, reduces tremor in a rat model and levodopa-induced dyskinesias in a monkey model

1 reference

https://pubmed.ncbi.nlm.nih.gov/21562283

12 December 2020

based on heuristic

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Molecular mechanisms of L-DOPA-induced dyskinesia

1 reference

https://pubmed.ncbi.nlm.nih.gov/21562283

12 December 2020

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Pimavanserin, a serotonin(2A) receptor inverse agonist, for the treatment of parkinson's disease psychosis

1 reference

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12 December 2020

based on heuristic

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Neuropsychiatric behaviors in the MPTP marmoset model of Parkinson's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21562283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serotonin 2A receptors and visual hallucinations in Parkinson disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/21562283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

5-HT2A receptor levels increase in MPTP-lesioned macaques treated chronically with L-DOPA.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21562283

12 December 2020

based on heuristic

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Increased 5-HT2A receptors in the temporal cortex of parkinsonian patients with visual hallucinations

1 reference

https://pubmed.ncbi.nlm.nih.gov/21562283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methylenedioxyamphetamine (MDA) and methylenedioxymethamphetamine (MDMA) cause selective ablation of serotonergic axon terminals in forebrain: immunocytochemical evidence for neurotoxicity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21562283

12 December 2020

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3,4-Methylenedioxymethamphetamine (MDMA): stereoselective interactions at brain 5-HT1 and 5-HT2 receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/21562283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemical pathophysiology of Parkinson's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21562283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacologic profile of MDMA (3,4-methylenedioxymethamphetamine) at various brain recognition sites

1 reference

https://pubmed.ncbi.nlm.nih.gov/21562283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Open pilot trial of ritanserin in parkinsonism.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21562283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nomifensine in parkinsonism

1 reference

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12 December 2020

based on heuristic

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Nomifensine in Parkinson's disease

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dopamine uptake in serotoninergic terminals in vitro: A valuable tool for the histochemical differentiation of catecholaminergic and serotoninergic terminals in rat cerebral structures

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro uptake of dopamine in serotoninergic nerve terminals: a fluorescence histochemical study on vibratome sections of the rat cerebral cortex

1 reference

https://pubmed.ncbi.nlm.nih.gov/21562283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/21562283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism in the common marmoset.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21562283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nomifensine: effect in Parkinsonian patients not receiving levodopa

1 reference

https://pubmed.ncbi.nlm.nih.gov/21562283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of the R(-) and S(+) isomers of MDA and MDMA on phosphatidyl inositol turnover in cultured cells expressing 5-HT2A or 5-HT2C receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/21562283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of 5-HT2 receptors facilitates depolarization of neocortical neurons by N-methyl-D-aspartate.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21562283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serotonin induces excitatory postsynaptic potentials in apical dendrites of neocortical pyramidal cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21562283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biological profile of L-745,870, a selective antagonist with high affinity for the dopamine D4 receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/21562283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Entacapone enhances the response to levodopa in parkinsonian patients with motor fluctuations. Nomecomt Study Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/21562283

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.1171-11.2011

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31 January 2020

1 reference

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31 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21562283%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

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