The mucin MUC4 and its membrane partner ErbB2 regulate biological properties of human CAPAN-2 pancreatic cancer cells via different signalling pathways (Q34185812)

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English	The mucin MUC4 and its membrane partner ErbB2 regulate biological properties of human CAPAN-2 pancreatic cancer cells via different signalling pathways	scientific article

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scholarly article

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Europe PubMed Central

31 July 2017

The mucin MUC4 and its membrane partner ErbB2 regulate biological properties of human CAPAN-2 pancreatic cancer cells via different signalling pathways (English)

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Europe PubMed Central

31 July 2017

pancreatic cancer

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based on heuristic

inferred from title

Nicolas Skrypek

2

object named as

Nicolas Skrypek

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Nicolas Jonckheere

object named as

Nicolas Jonckheere

1

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Jean-Luc Desseyn

object named as

Jean-Luc Desseyn

8

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Isabelle Van Seuningen

object named as

Isabelle Van Seuningen

11

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author name string

Nicolas Skrypek

2

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Europe PubMed Central

31 July 2017

Johann Merlin

3

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Europe PubMed Central

31 July 2017

Anne Frédérique Dessein

4

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Europe PubMed Central

31 July 2017

Patrick Dumont

5

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Europe PubMed Central

31 July 2017

Emmanuelle Leteurtre

6

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Europe PubMed Central

31 July 2017

Ann Harris

7

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Europe PubMed Central

31 July 2017

Christiane Susini

9

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Europe PubMed Central

31 July 2017

Frédéric Frénois

10

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Europe PubMed Central

31 July 2017

language of work or name

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publication date

29 February 2012

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Europe PubMed Central

31 July 2017

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Europe PubMed Central

31 July 2017

7

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Europe PubMed Central

31 July 2017

2

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Europe PubMed Central

31 July 2017

e32232

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Europe PubMed Central

31 July 2017

copyright license

Creative Commons Attribution 4.0 International

29 February 2012

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April 2022 Public Data File from Crossref

copyright status

0 references

Mucins and pancreatic cancer.

1 reference

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Tumor microenvironment and progression of pancreatic cancer.

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Galectin-3 regulates MUC1 and EGFR cellular distribution and EGFR downstream pathways in pancreatic cancer cells

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5 July 2018

Novel INTeraction of MUC4 and galectin: potential pathobiological implications for metastasis in lethal pancreatic cancer.

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Interaction between circulating galectin-3 and cancer-associated MUC1 enhances tumour cell homotypic aggregation and prevents anoikis.

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Muc4/MUC4 functions and regulation in cancer

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Alterations in integrin expression modulates invasion of pancreatic cancer cells

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The membrane-bound mucins: From cell signalling to transcriptional regulation and expression in epithelial cancers.

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Tumour growth and resistance to gemcitabine of pancreatic cancer cells are decreased by AP-2alpha overexpression.

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Signal integration by JNK and p38 MAPK pathways in cancer development

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The membrane-bound mucins: how large O-glycoproteins play key roles in epithelial cancers and hold promise as biological tools for gene-based and immunotherapies

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MUC4 involvement in ErbB2/ErbB3 phosphorylation and signaling in response to airway cell mechanical injury

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CA125/MUC16 is dispensable for mouse development and reproduction

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Lectin-epithelial interactions in the human colon.

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The role of the tumor microenvironment in the progression of pancreatic cancer

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5 July 2018

MUC4 mucin interacts with and stabilizes the HER2 oncoprotein in human pancreatic cancer cells

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Phosphatase-mediated crosstalk between MAPK signaling pathways in the regulation of cell survival

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Precursors to pancreatic cancer

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Human MUC4 mucin induces ultra-structural changes and tumorigenicity in pancreatic cancer cells

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Materializing the potential of small interfering RNA via a tumor-targeting nanodelivery system.

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Tumor-stroma interactions in pancreatic ductal adenocarcinoma

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Contribution of membrane mucins to tumor progression through modulation of cellular growth signaling pathways

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5 July 2018

Regulation of the human mucin MUC4 by taurodeoxycholic and taurochenodeoxycholic bile acids in oesophageal cancer cells is mediated by hepatocyte nuclear factor 1alpha.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3290552

5 July 2018

The murine Muc2 mucin gene is transcriptionally regulated by the zinc-finger GATA-4 transcription factor in intestinal cells

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5 July 2018

Mucins in cancer: protection and control of the cell surface

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Transcriptional regulation of human mucin MUC4 by bile acids in oesophageal cancer cells is promoter-dependent and involves activation of the phosphatidylinositol 3-kinase signalling pathway

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Cell signaling through membrane mucins

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Cloning, chromosomal localization and characterization of the murine mucin gene orthologous to human MUC4.

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TGF-beta signaling in tumor suppression and cancer progression

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Structural organization and classification of the human mucin genes

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Characterization of human mucin gene MUC4 promoter: importance of growth factors and proinflammatory cytokines for its regulation in pancreatic cancer cells.

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AP-1 in cell proliferation and survival

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Progression model for pancreatic cancer.

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Sequence of the 5'-flanking region and promoter activity of the human mucin gene MUC5B in different phenotypes of colon cancer cells

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Complete sequence of the human mucin MUC4: a putative cell membrane-associated mucin

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Human mucin gene MUC4: organization of its 5'-region and polymorphism of its central tandem repeat array

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Molecular cloning and chromosomal localization of a novel human tracheo-bronchial mucin cDNA containing tandemly repeated sequences of 48 base pairs

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5 July 2018

HER2 overexpression correlates with survival after curative resection of pancreatic cancer.

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Muc4/Sialomucin Complex, the Intramembrane ErbB2 Ligand, Translocates ErbB2 to the Apical Surface in Polarized Epithelial Cells

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A role for human MUC4 mucin gene, the ErbB2 ligand, as a target of TGF-beta in pancreatic carcinogenesis.

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Expression of the beta 6 integrin subunit in development, neoplasia and tissue repair suggests a role in epithelial remodeling.

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[MUC genes: a superfamily of genes? Towards a functional classification of human apomucins]

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10.1371/JOURNAL.PONE.0032232

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Europe PubMed Central

31 July 2017

2012PLoSO...732232J

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release_3ykkatc62jgylb6unzyne26ury

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https://api.fatcat.wiki/v0/release/3ykkatc62jgylb6unzyne26ury

24 November 2022

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mapped directly with Wikidata item

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Europe PubMed Central

31 July 2017

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Europe PubMed Central

31 July 2017

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