Mechanisms of platelet-derived growth factor-induced chemotaxis (Q34199550)

31 July 2017

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title

Mechanisms of platelet-derived growth factor-induced chemotaxis (English)

1 reference

31 July 2017

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L Rönnstrand

1

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PubMed ID

11275976

31 July 2017

C H Heldin

series ordinal

2

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PubMed ID

11275976

31 July 2017

language of work or name

English

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publication date

1 March 2001

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International Journal of Cancer

31 July 2017

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31 July 2017

91

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31 July 2017

6

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31 July 2017

757-762

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Cell migration: a physically integrated molecular process

31 July 2017

1 reference

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Mutations of the platelet-derived growth factor receptor that cause a loss of ligand-induced conformational change, subtle changes in kinase activity, and impaired ability to stimulate DNA synthesis

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Autophosphorylation of the PDGF receptor in the kinase insert region regulates interactions with cell proteins

21 January 2018

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A glioma-derived PDGF A chain homodimer has different functional activities from a PDGF AB heterodimer purified from human platelets.

21 January 2018

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Both homodimeric isoforms of PDGF (AA and BB) have mitogenic and chemotactic activity and stimulate phosphoinositol turnover

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Relative platelet-derived growth factor receptor subunit expression determines cell migration to different dimeric forms of PDGF.

21 January 2018

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Signaling by distinct classes of phosphoinositide 3-kinases

21 January 2018

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Phosphatidylinositol 3-kinase-independent signal transduction pathway for platelet-derived growth factor-induced chemotaxis

21 January 2018

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The lipid products of phosphoinositide 3-kinase increase cell motility through protein kinase C.

21 January 2018

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Signaling to Rho GTPases

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Activation of phosphoinositide 3-kinase is required for PDGF-stimulated membrane ruffling

21 January 2018

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Involvement of phosphatidylinositide 3'-kinase and Rac in platelet-derived growth factor-induced actin reorganization and chemotaxis

21 January 2018

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Platelet-derived growth factor and fibronectin-stimulated migration are differentially regulated by the Rac and extracellular signal-regulated kinase pathways.

21 January 2018

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Tyr-716 in the platelet-derived growth factor beta-receptor kinase insert is involved in GRB2 binding and Ras activation

21 January 2018

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Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases

21 January 2018

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Position independence and proper developmental control of gamma-globin gene expression require both a 5' locus control region and a downstream sequence element

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The chemotactic response to PDGF-BB: evidence of a role for Ras.

21 January 2018

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Mitogen-activated protein kinase activation mediates PDGF-directed migration of RPE cells

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From receptors to stress-activated MAP kinases

21 January 2018

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A Role for p38MAPK/HSP27 Pathway in Smooth Muscle Cell Migration

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Proteins regulating Ras and its relatives

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Tandem SH2 binding sites mediate the RasGAP-RhoGAP interaction: a conformational mechanism for SH3 domain regulation

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Identification of the Abl- and rasGAP-associated 62 kDa protein as a docking protein, Dok

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A role for Cdc42 in macrophage chemotaxis

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Regulation of chemotaxis by the platelet-derived growth factor receptor-beta

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Role of p120 Ras-GAP in directed cell movement

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Overactivation of phospholipase C-gamma1 renders platelet-derived growth factor beta-receptor-expressing cells independent of the phosphatidylinositol 3-kinase pathway for chemotaxis.

21 January 2018

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The PDGF receptor phosphorylates Tyr 138 in the c-Src SH3 domain in vivo reducing peptide ligand binding

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Multiple roles for Src in a PDGF-stimulated cell

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Src family kinases are required for integrin but not PDGFR signal transduction.

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No requirement for src family kinases for PDGF signaling in fibroblasts expressing SV40 large T antigen

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Signaling through focal adhesion kinase

21 January 2018

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Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice

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FAK integrates growth-factor and integrin signals to promote cell migration

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The GRB family of SH2 domain proteins

21 January 2018

1 reference

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Grb7 is a downstream signaling component of platelet-derived growth factor alpha- and beta-receptors

21 January 2018

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Grb10, a positive, stimulatory signaling adapter in platelet-derived growth factor BB-, insulin-like growth factor I-, and insulin-mediated mitogenesis

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1 reference

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Identification of a putative Syp substrate, the PDGF beta receptor

21 January 2018

1 reference

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Localization and down-regulating role of the protein tyrosine phosphatase PTP2C in membrane ruffles of PDGF-stimulated cells

21 January 2018

1 reference

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The phosphotyrosine phosphatase PTP1D, but not PTP1C, is an essential mediator of fibroblast proliferation induced by tyrosine kinase and G protein-coupled receptors

21 January 2018

1 reference

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Protein-tyrosine phosphatase Shp-2 regulates cell spreading, migration, and focal adhesion

21 January 2018

1 reference

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Structure and function of the low Mr phosphotyrosine protein phosphatases

21 January 2018

1 reference

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PDGF receptor as a specific in vivo target for low M(r) phosphotyrosine protein phosphatase

21 January 2018

1 reference

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Low molecular weight protein-tyrosine phosphatase tyrosine phosphorylation by c-Src during platelet-derived growth factor-induced mitogenesis correlates with its subcellular targeting.

21 January 2018

1 reference

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The low M(r) protein-tyrosine phosphatase is involved in Rho-mediated cytoskeleton rearrangement after integrin and platelet-derived growth factor stimulation.

21 January 2018

1 reference

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Sphingosine 1-phosphate stimulates rho-mediated tyrosine phosphorylation of focal adhesion kinase and paxillin in Swiss 3T3 fibroblasts

21 January 2018

1 reference

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Sphingosine-1-phosphate inhibits PDGF-induced chemotaxis of human arterial smooth muscle cells: spatial and temporal modulation of PDGF chemotactic signal transduction

21 January 2018

1 reference

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10.1002/1097-0215(200002)9999:9999<::AID-IJC1136>3.0.CO;2-J

21 January 2018

Identifiers

DOI

1 reference

31 July 2017

1 reference

PubMed ID

11275976