Secreted and membrane-bound isoforms of protease ADAM9 have opposing effects on breast cancer cell migration. (Q34203948)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20736367%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

title

Secreted and membrane-bound isoforms of protease ADAM9 have opposing effects on breast cancer cell migration (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20736367%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

1 reference

1

1 reference

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11 February 2020

author name string

Alex Toker

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20736367%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

language of work or name

English

0 references

publication date

24 August 2010

1 reference

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11 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20736367%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

volume

70

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20736367%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

issue

20

1 reference

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11 February 2020

page(s)

8187-8198

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20736367%20AND%20SRC:MED&resulttype=core&format=json

Inhibition of platelets and tumor cell adhesion by the disintegrin domain of human ADAM9 to collagen I under dynamic flow conditions.

11 February 2020

cites work

1 reference

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ADAM10, the rate-limiting protease of regulated intramembrane proteolysis of Notch and other proteins, is processed by ADAMS-9, ADAMS-15, and the gamma-secretase

28 July 2018

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A disintegrin and metalloproteinase (ADAM)-mediated ectodomain shedding of ADAM10.

28 July 2018

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Identification of genes that regulate epithelial cell migration using an siRNA screening approach

28 July 2018

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Role of ADAM-9 disintegrin-cysteine-rich domains in human keratinocyte migration

28 July 2018

1 reference

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Reactive oxygen species mediate androgen receptor- and serum starvation-elicited downstream signaling of ADAM9 expression in human prostate cancer cells

28 July 2018

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Genomic and transcriptional aberrations linked to breast cancer pathophysiologies

28 July 2018

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A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes

28 July 2018

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Oxidative stress induces ADAM9 protein expression in human prostate cancer cells

28 July 2018

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ADAM-9 (MDC-9/meltrin-gamma), a member of the a disintegrin and metalloproteinase family, regulates myeloma-cell-induced interleukin-6 production in osteoblasts by direct interaction with the alpha(v)beta5 integrin

28 July 2018

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Overexpression of ADAM9 enhances growth factor-mediated recycling of E-cadherin in human colon cancer cell line HT29 cells

28 July 2018

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Adam-9 expression and regulation in human skin melanoma and melanoma cell lines

28 July 2018

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Tumor-stroma interactions: their role in the control of tumor cell invasion.

28 July 2018

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ADAM15 decreases integrin alphavbeta3/vitronectin-mediated ovarian cancer cell adhesion and motility in an RGD-dependent fashion.

28 July 2018

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Increased expression of ADAM family members in human breast cancer and breast cancer cell lines

28 July 2018

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ADAM 12 cleaves extracellular matrix proteins and correlates with cancer status and stage

28 July 2018

1 reference

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The disintegrin domain of ADAM9: a ligand for multiple beta1 renal integrins

28 July 2018

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HB-EGF is a potent inducer of tumor growth and angiogenesis

28 July 2018

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Evidence of antiangiogenic and antimetastatic activities of the recombinant disintegrin domain of metargidin

28 July 2018

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Role of tissue stroma in cancer cell invasion

28 July 2018

1 reference

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Expression of ADAM-9 mRNA and protein in human breast cancer

28 July 2018

1 reference

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The ADAMs family of metalloproteases: multidomain proteins with multiple functions

28 July 2018

1 reference

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Mice lacking the metalloprotease-disintegrin MDC9 (ADAM9) have no evident major abnormalities during development or adult life.

28 July 2018

1 reference

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Proteolytic exposure of a cryptic site within collagen type IV is required for angiogenesis and tumor growth in vivo

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955804

Pin1 is overexpressed in breast cancer and cooperates with Ras signaling in increasing the transcriptional activity of c-Jun towards cyclin D1.

28 July 2018

1 reference

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The cysteine-rich domain of human ADAM 12 supports cell adhesion through syndecans and triggers signaling events that lead to beta1 integrin-dependent cell spreading

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955804

Meltrin gamma(ADAM-9) mediates cellular adhesion through alpha(6)beta(1 )integrin, leading to a marked induction of fibroblast cell motility

28 July 2018

1 reference

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SUM-159PT cells: a novel estrogen independent human breast cancer model system

28 July 2018

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Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-beta and promotes tumor invasion and angiogenesis

28 July 2018

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Distinctive gene expression patterns in human mammary epithelial cells and breast cancers

28 July 2018

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A metalloprotease-disintegrin, MDC9/meltrin-gamma/ADAM9 and PKCdelta are involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor.

28 July 2018

1 reference

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Induction of cell migration by matrix metalloprotease-2 cleavage of laminin-5

28 July 2018

1 reference

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Matrix metalloproteinases as insulin-like growth factor binding protein-degrading proteinases

28 July 2018

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The degradation of human endothelial cell-derived perlecan and release of bound basic fibroblast growth factor by stromelysin, collagenase, plasmin, and heparanases

28 July 2018

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The integrin alpha 6 beta 4 is a laminin receptor

28 July 2018

1 reference

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The ADAMs: signalling scissors in the tumour microenvironment

28 July 2018

1 reference

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Urinary metalloproteinases: noninvasive biomarkers for breast cancer risk assessment.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955804

ADAM15 gene structure and differential alternative exon use in human tissues.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955804

Proteolytic processing of delta-like 1 by ADAM proteases

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955804

A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955804

How ADAM-9 and ADAM-11 differentially from estrogen receptor predict response to tamoxifen treatment in patients with recurrent breast cancer: a retrospective study

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955804

A role for ADAM12 in breast tumor progression and stromal cell apoptosis.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955804

A secreted form of ADAM9 promotes carcinoma invasion through tumor-stromal interactions

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955804

Tumor cell invasiveness correlates with changes in integrin expression and localization

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955804

ADAM12/syndecan-4 signaling promotes beta 1 integrin-dependent cell spreading through protein kinase Calpha and RhoA.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955804

ADAM13 disintegrin and cysteine-rich domains bind to the second heparin-binding domain of fibronectin

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955804

Critical function for ADAM9 in mouse prostate cancer

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20736367

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Early response cytokines and innate immunity: essential roles for TNF receptor 1 and type I IL-1 receptor during Escherichia coli pneumonia in mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20736367

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1158/0008-5472.CAN-09-4231

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20736367%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20736367%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

PubMed publication ID

20736367

1 reference