E2F1 mediated apoptosis induced by the DNA damage response is blocked by EBV nuclear antigen 3C in lymphoblastoid cells. (Q34205875)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22438805%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

title

E2F1 mediated apoptosis induced by the DNA damage response is blocked by EBV nuclear antigen 3C in lymphoblastoid cells (English)

1 reference

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26 January 2020

0 references

1 reference

1

1 reference

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26 January 2020

6

Erle S Robertson

1 reference

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26 January 2020

author name string

Jie Lu

2

1 reference

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26 January 2020

Lise Morizur

3

1 reference

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26 January 2020

Santosh K Upadhyay

4

1 reference

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26 January 2020

Mahadesh Prasad Aj

5

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26 January 2020

publication date

15 March 2012

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26 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22438805%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

volume

8

1 reference

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26 January 2020

page(s)

e1002573

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26 January 2020

issue

3

1 reference

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Creative Commons Attribution 4.0 International

26 January 2020

copyright license

start time

15 March 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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The latency-associated nuclear antigen encoded by Kaposi's sarcoma-associated herpesvirus activates two major essential Epstein-Barr virus latent promoters

5 July 2018

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Physical and functional interactions between the corepressor CtBP and the Epstein-Barr virus nuclear antigen EBNA3C

5 July 2018

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Selective induction of E2F1 in response to DNA damage, mediated by ATM-dependent phosphorylation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3305458

Epstein-Barr virus nuclear protein EBNA-3C interacts with the human metastatic suppressor Nm23-H1: a molecular link to cancer metastasis

5 July 2018

1 reference

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Role of the p53-homologue p73 in E2F1-induced apoptosis

5 July 2018

1 reference

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Role for the p53 homologue p73 in E2F-1-induced apoptosis

5 July 2018

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Epstein-barr virus nuclear antigen 3C activates the latent membrane protein 1 promoter in the presence of Epstein-Barr virus nuclear antigen 2 through sequences encompassing an spi-1/Spi-B binding site

5 July 2018

1 reference

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Epstein-Barr virus EBNA3C can disrupt multiple cell cycle checkpoints and induce nuclear division divorced from cytokinesis.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3305458

Alternative pathways for the extension of cellular life span: inactivation of p53/pRb and expression of telomerase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3305458

Interaction between ubiquitin-protein ligase SCFSKP2 and E2F-1 underlies the regulation of E2F-1 degradation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3305458

Epstein-Barr virus-mediated B-cell proliferation is dependent upon latent membrane protein 1, which simulates an activated CD40 receptor

5 July 2018

1 reference

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DDB, a putative DNA repair protein, can function as a transcriptional partner of E2F1.

5 July 2018

1 reference

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E2F1-induced apoptosis requires DNA binding but not transactivation and is inhibited by the retinoblastoma protein through direct interaction

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3305458

Regulation of E2F through ubiquitin-proteasome-dependent degradation: stabilization by the pRB tumor suppressor protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3305458

Degradation of E2F by the ubiquitin-proteasome pathway: regulation by retinoblastoma family proteins and adenovirus transforming proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3305458

The retinoblastoma gene product protects E2F-1 from degradation by the ubiquitin-proteasome pathway

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3305458

A conserved domain of the Epstein-Barr virus nuclear antigens 3A and 3C binds to a discrete domain of Jkappa

5 July 2018

1 reference

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EBNA-2 and EBNA-3C extensively and mutually exclusively associate with RBPJkappa in Epstein-Barr virus-transformed B lymphocytes

5 July 2018

1 reference

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Inhibition of E2F-1 transactivation by direct binding of the retinoblastoma protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3305458

Expression of transcription factor E2F1 induces quiescent cells to enter S phase

5 July 2018

1 reference

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Overexpression of E2F-1 in rat embryo fibroblasts leads to neoplastic transformation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3305458

E2F1 overexpression in quiescent fibroblasts leads to induction of cellular DNA synthesis and apoptosis.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3305458

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

5 July 2018

1 reference

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Differential regulation of E2F1 apoptotic target genes in response to DNA damage.

5 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002573

Binding to DNA and the retinoblastoma gene product promoted by complex formation of different E2F family members

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002573

Compensation and specificity of function within the E2F family.

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002573

Detection of Epstein-Barr virus in T-cell prolymphocytic leukemia cells in vitro

21 January 2018

1 reference

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Functional interplay between E2F1 and chemotherapeutic drugs defines immediate E2F1 target genes crucial for cancer cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002573

Identification of the nuclear localization signals within the Epstein-Barr virus EBNA-6 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002573

The paradox of E2F1: oncogene and tumor suppressor gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002573

DNA damage-dependent acetylation of p73 dictates the selective activation of apoptotic target genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002573

Apaf-1 is a transcriptional target for E2F and p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002573

E2F-1 functions in mice to promote apoptosis and suppress proliferation

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22438805

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Tumor induction and tissue atrophy in mice lacking E2F-1

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22438805

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Activation of B-Myb by E2F1 in hepatocellular carcinoma

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22438805

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PPAT.1002573

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22438805%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22438805%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22438805%20AND%20SRC:MED&resulttype=core&format=json