The pan-ErbB negative regulator Lrig1 is an intestinal stem cell marker that functions as a tumor suppressor (Q34264864)

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27 January 2020

title

The pan-ErbB negative regulator Lrig1 is an intestinal stem cell marker that functions as a tumor suppressor (English)

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9

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Shawn Levy

10

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Bruce J Aronow

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Kevin M Haigis

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author name string

Anne E Powell

1

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Yang Wang

2

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Yina Li

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Emily J Poulin

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Anna L Means

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Mary K Washington

6

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James N Higginbotham

7

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Alwin Juchheim

8

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Yan Guo

11

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Yu Shyr

12

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Jeffrey L Franklin

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Robert J Coffey

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language of work or name

English

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publication date

1 March 2012

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27 January 2020

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27 January 2020

volume

149

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page(s)

146-158

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issue

1

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Single-molecule transcript counting of stem-cell markers in the mouse intestine

27 January 2020

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1 reference

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Interconversion between intestinal stem cell populations in distinct niches

6 July 2018

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A reserve stem cell population in small intestine renders Lgr5-positive cells dispensable

6 July 2018

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6 July 2018

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6 July 2018

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Intestinal epithelial stem cells do not protect their genome by asymmetric chromosome segregation

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Sox9 expression marks a subset of CD24-expressing small intestine epithelial stem cells that form organoids in vitro

6 July 2018

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6 July 2018

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Inflammation and proliferation act together to mediate intestinal cell fusion

6 July 2018

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Lrig1 expression defines a distinct multipotent stem cell population in mammalian epidermis

6 July 2018

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Transcription factor achaete scute-like 2 controls intestinal stem cell fate

6 July 2018

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Establishment of conditionally immortalized epithelial cell lines from the intestinal tissue of adult normal and transgenic mice

6 July 2018

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Crypt stem cells as the cells-of-origin of intestinal cancer

6 July 2018

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6 July 2018

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Suppression of the negative regulator LRIG1 contributes to ErbB2 overexpression in breast cancer

6 July 2018

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Bmi1 is expressed in vivo in intestinal stem cells

6 July 2018

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6 July 2018

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Lrig1 is an endogenous inhibitor of Ret receptor tyrosine kinase activation, downstream signaling, and biological responses to GDNF.

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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LRIG1 is a novel negative regulator of the Met receptor and opposes Met and Her2 synergy

6 July 2018

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6 July 2018

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Single-cell expression profiling of human epidermal stem and transit-amplifying cells: Lrig1 is a regulator of stem cell quiescence

6 July 2018

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A soluble ectodomain of LRIG1 inhibits cancer cell growth by attenuating basal and ligand-dependent EGFR activity

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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LRIG1 and epidermal growth factor receptor in renal cell carcinoma: a quantitative RT--PCR and immunohistochemical analysis

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Purification and characterization of mouse hematopoietic stem cells

6 July 2018

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Upregulation of LRIG1 suppresses malignant glioma cell growth by attenuating EGFR activity

6 July 2018

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28 October 2018

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LRIG-1 provides a novel prognostic predictor in squamous cell carcinoma of the skin: immunohistochemical analysis for 38 cases.

28 October 2018

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Rapid colorectal adenoma formation initiated by conditional targeting of the Apc gene.

28 October 2018

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Gene expression of CD24 core polypeptide molecule in normal rat tissues and human tumor cell lines

28 October 2018

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28 October 2018

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12 December 2020

The clonogen content of murine intestinal crypts: dependence on radiation dose used in its determination

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12 December 2020

The number of clonogenic cells in crypts in three regions of murine large intestine

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12 December 2020

LRIG1 expression in colorectal cancer

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12 December 2020

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