Transcriptional regulation of ferritin and antioxidant genes by HIPK2 under genotoxic stress (Q34273684)

1 August 2017

title

Transcriptional regulation of ferritin and antioxidant genes by HIPK2 under genotoxic stress (English)

1 reference

1 August 2017

1 reference

2

Kenta Iwasaki

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20980392

11 August 2024

author name string

Kiros Hailemariam

1

1 reference

1 August 2017

Bo-Wen Huang

3

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1 August 2017

Kensuke Sakamoto

4

1 reference

1 August 2017

Yoshiaki Tsuji

5

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1 August 2017

language of work or name

English

0 references

publication date

27 October 2010

1 reference

full work available at URL

1 August 2017

http://jcs.biologists.org/content/123/22/3863.full.pdf

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20980392

http://jcs.biologists.org/cgi/content/abstract/123/22/3863

11 August 2024

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20980392

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20980392/?tool=EBI

11 August 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20980392

https://europepmc.org/articles/PMC2972272

11 August 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20980392

https://doi.org/10.1242/jcs.073627

11 August 2024

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20980392

11 August 2024

published in

Journal of Cell Science

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1 August 2017

volume

123

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1 August 2017

issue

Pt 22

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1 August 2017

page(s)

3863-3871

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Regulation of genotoxic stress response by homeodomain-interacting protein kinase 2 through phosphorylation of cyclic AMP response element-binding protein at serine 271.

1 August 2017

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Inhibition of HIF-1alpha activity by homeodomain-interacting protein kinase-2 correlates with sensitization of chemoresistant cells to undergo apoptosis.

6 July 2018

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ATF-1 is a hypoxia-responsive transcriptional activator of skeletal muscle mitochondrial-uncoupling protein 3.

6 July 2018

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Elevated intracellular calcium increases ferritin H expression through an NFAT-independent post-transcriptional mechanism involving mRNA stabilization

6 July 2018

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HIPK2: a multitalented partner for transcription factors in DNA damage response and development.

6 July 2018

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HIPK2 represses beta-catenin-mediated transcription, epidermal stem cell expansion, and skin tumorigenesis

6 July 2018

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PIAS3 interacts with ATF1 and regulates the human ferritin H gene through an antioxidant-responsive element

6 July 2018

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HIPK2: a versatile switchboard regulating the transcription machinery and cell death

6 July 2018

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Essential function of HIPK2 in TGFbeta-dependent survival of midbrain dopamine neurons

6 July 2018

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Roles of HIPK1 and HIPK2 in AML1- and p300-dependent transcription, hematopoiesis and blood vessel formation

6 July 2018

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The role of iron regulatory proteins in mammalian iron homeostasis and disease

6 July 2018

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Hemin-mediated regulation of an antioxidant-responsive element of the human ferritin H gene and role of Ref-1 during erythroid differentiation of K562 cells

6 July 2018

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JunD activates transcription of the human ferritin H gene through an antioxidant response element during oxidative stress

6 July 2018

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Phosphorylation by the DHIPK2 protein kinase modulates the corepressor activity of Groucho

6 July 2018

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Homeodomain-interacting protein kinase-2 mediates CtBP phosphorylation and degradation in UV-triggered apoptosis

6 July 2018

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Iron metabolism and toxicity

6 July 2018

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Nrf2-Keap1 defines a physiologically important stress response mechanism

6 July 2018

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Interaction of Brn3a and HIPK2 mediates transcriptional repression of sensory neuron survival

6 July 2018

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Balancing acts: molecular control of mammalian iron metabolism

6 July 2018

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Role of CREB in transcriptional regulation of CCAAT/enhancer-binding protein beta gene during adipogenesis

6 July 2018

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Homeodomain interacting protein kinase 2 promotes apoptosis by downregulating the transcriptional corepressor CtBP.

6 July 2018

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Ferritin: At the Crossroads of Iron and Oxygen Metabolism

6 July 2018

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Ferritin, iron homeostasis, and oxidative damage1,2 1Guest Editor: Mario Comporti 2This article is part of a series of reviews on “Iron and Cellular Redox Status.” The full list of papers may be found on the homepage of the journal.

6 July 2018

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MSK1 and MSK2 are required for the mitogen- and stress-induced phosphorylation of CREB and ATF1 in fibroblasts

6 July 2018

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Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis.

6 July 2018

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6 July 2018

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6 July 2018

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Repression of the heavy ferritin chain increases the labile iron pool of human K562 cells

6 July 2018

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6 July 2018

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Human homeodomain-interacting protein kinase-2 (HIPK2) is a member of the DYRK family of protein kinases and maps to chromosome 7q32-q34.

6 July 2018

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Coordinate transcriptional and translational regulation of ferritin in response to oxidative stress

6 July 2018

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CREB: a stimulus-induced transcription factor activated by a diverse array of extracellular signals

6 July 2018

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6 July 2018

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Protection from oxidative stress-induced apoptosis in cortical neuronal cultures by iron chelators is associated with enhanced DNA binding of hypoxia-inducible factor-1 and ATF-1/CREB and increased expression of glycolytic enzymes, [...]

6 July 2018

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Stress-induced stimulation of early growth response gene-1 by p38/stress-activated protein kinase 2 is mediated by a cAMP-responsive promoter element in a MAPKAP kinase 2-independent manner

6 July 2018

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Coordinated regulation of iron-controlling genes, H-ferritin and IRP2, by c-MYC

6 July 2018

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6 July 2018

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Regulation of transcription by hypoxia requires a multiprotein complex that includes hypoxia-inducible factor 1, an adjacent transcription factor, and p300/CREB binding protein

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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The transcription factors ATF-1 and CREB-1 bind constitutively to the hypoxia-inducible factor-1 (HIF-1) DNA recognition site

6 July 2018

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Preferential repression of the H subunit of ferritin by adenovirus E1A in NIH-3T3 mouse fibroblasts

6 July 2018

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6 July 2018

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Phosphorylated CREB binds specifically to the nuclear protein CBP

6 July 2018

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6 July 2018

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6 July 2018

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Nuclear protein CBP is a coactivator for the transcription factor CREB

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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The homeodomain-interacting protein kinase 2 regulates insulin promoter factor-1/pancreatic duodenal homeobox-1 transcriptional activity

28 October 2018

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Glucose metabolism in cancer: importance of transcription factor-DNA interactions within a short segment of the proximal region og the type II hexokinase promoter

28 October 2018

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Genetic or pharmacological iron chelation prevents MPTP-induced neurotoxicity in vivo: a novel therapy for Parkinson's disease

28 October 2018

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Ferritin, iron homeostasis, and oxidative damage

28 October 2018

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Molecular mechanism of transcriptional repression of gelsolin in human breast cancer cells.

28 October 2018

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A CREB site in the BRCA1 proximal promoter acts as a constitutive transcriptional element

28 October 2018

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Activation of extracellular signal-regulated kinases and CREB/ATF-1 mediate the expression of CCAAT/enhancer binding proteins beta and -delta in preadipocytes

28 October 2018

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Inhibition of tumor growth and metastasis of human melanoma by intracellular anti-ATF-1 single chain Fv fragment.

28 October 2018

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Ferritin Heavy Chain Upregulation by NF-κB Inhibits TNFα-Induced Apoptosis by Suppressing Reactive Oxygen Species

28 October 2018

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Transcriptional regulation of the transforming growth factor-beta2 promoter by cAMP-responsive element-binding protein (CREB) and activating transcription factor-1 (ATF-1) is modulated by protein kinases and the coactivators p300 and CREB-binding pr

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20980392

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1242/JCS.073627

1 reference

1 August 2017

1 reference

1 August 2017

1 reference