Control of human PIRH2 protein stability: involvement of TIP60 and the proteosome (Q34287238)

1 August 2017

Control of human PIRH2 protein stability: involvement of TIP60 and the proteosome (English)

1 reference

1 August 2017

David E Neal

4

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author name string

Ian R Logan

1

1 reference

1 August 2017

Vasileia Sapountzi

2

1 reference

1 August 2017

Luke Gaughan

3

1 reference

1 August 2017

Craig N Robson

5

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1 August 2017

language of work or name

English

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publication date

29 December 2003

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Journal of Biological Chemistry

1 August 2017

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1 August 2017

279

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1 August 2017

12

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1 August 2017

11696-11704

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Live or let die: the cell's response to p53

1 August 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312712200

Ubiquitination, phosphorylation and acetylation: the molecular basis for p53 regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312712200

21 January 2018

Why is p53 acetylated?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312712200

The p53-Mdm2 module and the ubiquitin system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312712200

How the ubiquitin-proteasome system controls transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312712200

Emerging roles of ubiquitin in transcription regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312712200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312712200

The p53 and Mdm2 families in cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312712200

Amplification of a gene encoding a p53-associated protein in human sarcomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312712200

Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312712200

Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312712200

Mdm2 promotes the rapid degradation of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312712200

An intact HDM2 RING-finger domain is required for nuclear exclusion of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312712200

The MDM2 RING-finger domain is required to promote p53 nuclear export

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312712200

Identification of p53 sequence elements that are required for MDM2-mediated nuclear export

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312712200

Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312712200

Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312712200

The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312712200

ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312712200

The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312712200

Association of p19(ARF) with Mdm2 inhibits ubiquitin ligase activity of Mdm2 for tumor suppressor p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312712200

Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312712200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312712200

ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312712200

SUMO-1 modification of Mdm2 prevents its self-ubiquitination and increases Mdm2 ability to ubiquitinate p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312712200

Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312712200

Nucleolar Arf sequesters Mdm2 and activates p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312712200

Cooperative signals governing ARF-mdm2 interaction and nucleolar localization of the complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312712200

Regulation of HDM2 activity by the ribosomal protein L11

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312712200

Stabilization of p53 by p14ARF without relocation of MDM2 to the nucleolus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312712200

Activity of MDM2, a ubiquitin ligase, toward p53 or itself is dependent on the RING finger domain of the ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312712200

A TSG101/MDM2 regulatory loop modulates MDM2 degradation and MDM2/p53 feedback control

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312712200

p53 accumulation, defective cell proliferation, and early embryonic lethality in mice lacking tsg101.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312712200

The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312712200

Polyubiquitination of p53 by a ubiquitin ligase activity of p300.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312712200

Pirh2, a p53-induced ubiquitin-protein ligase, promotes p53 degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312712200

Cloning and characterization of an androgen receptor N-terminal-interacting protein with ubiquitin-protein ligase activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312712200

Identification of a cellular protein that specifically interacts with the essential cysteine region of the HIV-1 Tat transactivator

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312712200

Tip60 acetylates six lysines of a specific class in core histones in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312712200

Novel substrate specificity of the histone acetyltransferase activity of HIV-1-Tat interactive protein Tip60

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312712200

Tip60 is a nuclear hormone receptor coactivator

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312712200

Tip60 and histone deacetylase 1 regulate androgen receptor activity through changes to the acetylation status of the receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312712200

Acetylation of androgen receptor enhances coactivator binding and promotes prostate cancer cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312712200

Expression of Tip60, an androgen receptor coactivator, and its role in prostate cancer development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312712200

Molecular genetics of prostate cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312712200

The Bcl-3 oncoprotein acts as a bridging factor between NF-kappaB/Rel and nuclear co-regulators

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312712200

MYC recruits the TIP60 histone acetyltransferase complex to chromatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312712200

The acetyltransferase 60 kDa trans-acting regulatory protein of HIV type 1-interacting protein (Tip60) interacts with the translocation E26 transforming-specific leukaemia gene (TEL) and functions as a transcriptional co-repressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312712200

Tip60 is a co-repressor for STAT3

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312712200

Identification of new subunits of the multiprotein mammalian TRRAP/TIP60-containing histone acetyltransferase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312712200

A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312712200

Exchange of N-CoR corepressor and Tip60 coactivator complexes links gene expression by NF-kappaB and beta-amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312712200

Involvement of the TIP60 histone acetylase complex in DNA repair and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312712200

Multiple links between the NuA4 histone acetyltransferase complex and epigenetic control of transcription.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312712200

Acetylation of histone H4 by Esa1 is required for DNA double-strand break repair.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312712200

Tip60 is targeted to proteasome-mediated degradation by Mdm2 and accumulates after UV irradiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312712200

RING finger proteins: mediators of ubiquitin ligase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312712200

Phosphorylation-dependent ubiquitylation and degradation of androgen receptor by Akt require Mdm2 E3 ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312712200

Proteasome inhibitors disrupt the unfolded protein response in myeloma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312712200

Nucleocytoplasmic shuttling of p53 is essential for MDM2-mediated cytoplasmic degradation but not ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312712200

c-Myc proteolysis by the ubiquitin-proteasome pathway: stabilization of c-Myc in Burkitt's lymphoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312712200

The loss of mdm2 induces p53-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M312712200

21 January 2018

Identifiers

DOI

10.1074/JBC.M312712200

1 reference

1 August 2017

1 reference