The contribution of cell surface FcRn in monoclonal antibody serum uptake from the intestine in suckling rat pups (Q34299344)

1 August 2017

title

The contribution of cell surface FcRn in monoclonal antibody serum uptake from the intestine in suckling rat pups (English)

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1 August 2017

Philip R Cooper

1

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1 August 2017

Connie M Kliwinski

2

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1 August 2017

Robert A Perkinson

3

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1 August 2017

Edwin Ragwan

4

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1 August 2017

John R Mabus

5

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1 August 2017

Gordon D Powers

6

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1 August 2017

Haimanti Dorai

7

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1 August 2017

Jill Giles-Komar

8

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1 August 2017

Pamela J Hornby

9

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1 August 2017

publication date

7 October 2014

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Frontiers in Pharmacology

1 August 2017

published in

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1 August 2017

volume

5

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1 August 2017

page(s)

225

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Human and non-human primate intestinal FcRn expression and immunoglobulin G transcytosis

1 August 2017

cites work

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4188031

Abundant intracellular IgG in enterocytes and endoderm lacking FcRn

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4188031

Subcutaneous bioavailability of therapeutic antibodies as a function of FcRn binding affinity in mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4188031

Neonatal Fc receptor and IgG-based therapeutics

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4188031

N-Glycan Moieties in Neonatal Fc Receptor Determine Steady-state Membrane Distribution and Directional Transport of IgG.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4188031

FcRn: the neonatal Fc receptor comes of age.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4188031

Monoclonal antibody clearance. Impact of modulating the interaction of IgG with the neonatal Fc receptor

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4188031

Analysis of a family of antibodies with different half-lives in mice fails to find a correlation between affinity for FcRn and serum half-life

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4188031

Exocytosis of IgG as mediated by the receptor, FcRn: an analysis at the single-molecule level

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4188031

Lymphatic function, lymphangiogenesis, and cancer metastasis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4188031

The MHC class I-related receptor, FcRn, plays an essential role in the maternofetal transfer of gamma-globulin in humans

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4188031

Bidirectional FcRn-dependent IgG transport in a polarized human intestinal epithelial cell line

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4188031

Ontogenetic development and distribution of antibody transport and Fc receptor mRNA expression in rat intestine

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4188031

Beta 2-microglobulin co-distributes with the heavy chain of the intestinal IgG-Fc receptor throughout the transepithelial transport pathway of the neonatal rat.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4188031

Receptor-mediated transport of IgG

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4188031

The transmission of immunity from mother to young and the catabolism of immunoglobulins

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4188031

The transmission of immune globulins from the mother to the foetal and newborn young

6 July 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2014.00225

Humanized IgG1 variants with differential binding properties to the neonatal Fc receptor: relationship to pharmacokinetics in mice and primates.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2014.00225

Contribution of FcRn binding to intestinal uptake of IgG in suckling rat pups and human FcRn-transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2014.00225

Analysis of the pH dependence of the neonatal Fc receptor/immunoglobulin G interaction using antibody and receptor variants.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2014.00225

Engineering human IgG1 affinity to human neonatal Fc receptor: impact of affinity improvement on pharmacokinetics in primates

21 January 2018

1 reference

12 December 2020

Intestinal Transport and Processing of Immunoglobulin G in the Neonatal and Adult Rat

1 reference

12 December 2020

Pharmacokinetics of humanized monoclonal anti-tumor necrosis factor-{alpha} antibody and its neonatal Fc receptor variants in mice and cynomolgus monkeys

1 reference

12 December 2020

Endocytosis by absorptive cells in the middle segment of the suckling rat small intestine

1 reference

12 December 2020

The role of the Brambell receptor (FcRB) in liver: protection of endocytosed immunoglobulin G (IgG) from catabolism in hepatocytes rather than transport of IgG to bile

1 reference

12 December 2020

Expression of the neonatal Fc receptor, FcRn, on human intestinal epithelial cells

1 reference

12 December 2020

Influence of intestinal microflora on the tryptic activity during lactation in rats

1 reference

12 December 2020

Development of gastrointestinal mucosal barrier. I. The effect of age on intestinal permeability to macromolecules

1 reference

12 December 2020

Identifiers

DOI

10.3389/FPHAR.2014.00225

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1 August 2017

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1 August 2017

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