Regulation of Nrf2 transactivation domain activity. The differential effects of mitogen-activated protein kinase cascades and synergistic stimulatory effect of Raf and CREB-binding protein (Q34305832)

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English	Regulation of Nrf2 transactivation domain activity. The differential effects of mitogen-activated protein kinase cascades and synergistic stimulatory effect of Raf and CREB-binding protein	scientific article

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scholarly article

1 reference

Europe PubMed Central

1 August 2017

Regulation of Nrf2 transactivation domain activity. The differential effects of mitogen-activated protein kinase cascades and synergistic stimulatory effect of Raf and CREB-binding protein (English)

1 reference

Europe PubMed Central

1 August 2017

author name string

Guoxiang Shen

1

1 reference

Europe PubMed Central

1 August 2017

Vidya Hebbar

2

1 reference

Europe PubMed Central

1 August 2017

Sujit Nair

3

1 reference

Europe PubMed Central

1 August 2017

Changjiang Xu

4

1 reference

Europe PubMed Central

1 August 2017

Wenge Li

5

1 reference

Europe PubMed Central

1 August 2017

Wen Lin

6

1 reference

Europe PubMed Central

1 August 2017

Young-Sam Keum

7

1 reference

Europe PubMed Central

1 August 2017

Jiahuai Han

8

1 reference

Europe PubMed Central

1 August 2017

Michael A Gallo

9

1 reference

Europe PubMed Central

1 August 2017

A-N Tony Kong

10

1 reference

Europe PubMed Central

1 August 2017

language of work or name

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publication date

13 March 2004

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Europe PubMed Central

1 August 2017

Journal of Biological Chemistry

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Europe PubMed Central

1 August 2017

279

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Europe PubMed Central

1 August 2017

22

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Europe PubMed Central

1 August 2017

23052-23060

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Europe PubMed Central

1 August 2017

A major inducer of anticarcinogenic protective enzymes from broccoli: isolation and elucidation of structure

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Cancer chemoprevention: principles and prospects.

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An important function of Nrf2 in combating oxidative stress: detoxification of acetaminophen

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Nrf2, a Cap'n'Collar transcription factor, regulates induction of the heme oxygenase-1 gene

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Regulation of gamma-glutamylcysteine synthetase subunit gene expression by the transcription factor Nrf2.

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An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements

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Nrf2 is essential for protection against acute pulmonary injury in mice

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Transcription factor Nrf2 coordinately regulates a group of oxidative stress-inducible genes in macrophages

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Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region

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Impaired expression of glutathione synthetic enzyme genes in mice with targeted deletion of the Nrf2 basic-leucine zipper protein

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High sensitivity of Nrf2 knockout mice to acetaminophen hepatotoxicity associated with decreased expression of ARE-regulated drug metabolizing enzymes and antioxidant genes

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The Nrf2 transcription factor contributes both to the basal expression of glutathione S-transferases in mouse liver and to their induction by the chemopreventive synthetic antioxidants, butylated hydroxyanisole and ethoxyquin

1 reference

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Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain

1 reference

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Regulation of the antioxidant response element by protein kinase C-mediated phosphorylation of NF-E2-related factor 2

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Site-directed mutagenesis of cysteine to serine in the DNA binding region of Nrf2 decreases its capacity to upregulate antioxidant response element-mediated expression and antioxidant induction of NAD(P)H:quinone oxidoreductase1 gene

1 reference

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Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants

1 reference

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The Keap1 BTB/POZ dimerization function is required to sequester Nrf2 in cytoplasm

1 reference

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Keap1-dependent proteasomal degradation of transcription factor Nrf2 contributes to the negative regulation of antioxidant response element-driven gene expression

1 reference

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Increased protein stability as a mechanism that enhances Nrf2-mediated transcriptional activation of the antioxidant response element. Degradation of Nrf2 by the 26 S proteasome

1 reference

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Erk activation is required for Nrf2 nuclear localization during pyrrolidine dithiocarbamate induction of glutamate cysteine ligase modulatory gene expression in HepG2 cells

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Phosphorylation of Nrf2 at Ser-40 by protein kinase C regulates antioxidant response element-mediated transcription

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Inhibition of ERK and p38 MAP kinases inhibits binding of Nrf2 and induction of GCS genes

1 reference

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Human small Maf proteins form heterodimers with CNC family transcription factors and recognize the NF-E2 motif

1 reference

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Two domains of Nrf2 cooperatively bind CBP, a CREB binding protein, and synergistically activate transcription

1 reference

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Functional characterization of transcription regulators that interact with the electrophile response element

1 reference

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Phosphorylation by p44 MAP Kinase/ERK1 stimulates CBP histone acetyl transferase activity in vitro

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CBP associates with the p42/p44 MAPK enzymes and is phosphorylated following NGF treatment

1 reference

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Stimulation of p300-mediated transcription by the kinase MEKK1.

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21 January 2018

The transcriptional co-activators CBP and p300 are activated via phenylephrine through the p42/p44 MAPK cascade

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21 January 2018

MAPK signaling up-regulates the activity of hypoxia-inducible factors by its effects on p300

1 reference

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21 January 2018

Phosphorylation of transcriptional coactivator peroxisome proliferator-activated receptor (PPAR)-binding protein (PBP). Stimulation of transcriptional regulation by mitogen-activated protein kinase

1 reference

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21 January 2018

Activation of mitogen-activated protein kinase pathways induces antioxidant response element-mediated gene expression via a Nrf2-dependent mechanism

1 reference

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21 January 2018

Antioxidants and oxidants regulated signal transduction pathways

1 reference

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Curcumin activates the haem oxygenase-1 gene via regulation of Nrf2 and the antioxidant-responsive element

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The primary structure of p38 gamma: a new member of p38 group of MAP kinases

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Characterization of the structure and function of a new mitogen-activated protein kinase (p38beta)

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ERK6, a mitogen-activated protein kinase involved in C2C12 myoblast differentiation

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SAP kinase-3, a new member of the family of mammalian stress-activated protein kinases

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Characterization of the structure and function of the fourth member of p38 group mitogen-activated protein kinases, p38delta

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Sequence and structure-based prediction of eukaryotic protein phosphorylation sites

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Identification of the interactive interface and phylogenic conservation of the Nrf2-Keap1 system.

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Atypical protein kinase C mediates activation of NF-E2-related factor 2 in response to oxidative stress

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Phosphatidylinositol 3-kinase regulates nuclear translocation of NF-E2-related factor 2 through actin rearrangement in response to oxidative stress

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Identifiers

10.1074/JBC.M401368200

1 reference

Europe PubMed Central

1 August 2017

1 reference

Europe PubMed Central

1 August 2017

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