Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia (Q34314927)

1 August 2017

Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia (English)

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1 August 2017

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lymphoblastic leukemia

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67

Elaine Mardis

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1 August 2017

Kelly McCastlain

7

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Andrew S Moore

Andrew S Moore

44

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Richard C Harvey

Richard C Harvey

4

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Sarah K. Tasian

Sarah K Tasian

43

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Deborah L. White

Deborah L White

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Charles G. Mullighan

Charles G Mullighan

74

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John Easton

John Easton

15

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Malcolm A Smith

Malcolm A Smith

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Guido Marcucci

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Guido Marcucci

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1 August 2017

19

Ilaria Iacobucci

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Marina Konopleva

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Ching-Hon Pui

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Clara D Bloomfield

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Krzysztof Mrózek

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Jessica Kohlschmidt

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60

Elisabeth Paietta

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71

Stephen P Hunger

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Nyla A Heerema

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Cheryl L Willman

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Julie M Gastier-Foster

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Meenakshi Devidas

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Mignon L Loh

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Naomi J Winick

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Mary V Relling

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3

Debbie Payne-Turner

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6

Deqing Pei

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10

Guangchun Song

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13

Michael Rusch

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Kristy Boggs

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27

Shalini Reshmi

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35

Bhavin Vadodaria

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36

Heather Mulder

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48

Elizabeth A Raetz

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57

Wendy Stock

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58

Steven M Kornblau

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62

Sima Jeha

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65

Daniela S Gerhard

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1 August 2017

34

Donald Yergeau

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45

Frank Keller

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12

Jared Becksfort

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29

Erin Hedlund

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24

Steven W Paugh

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1 August 2017

47

James A Whitlock

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1 August 2017

14

Shann-Ching Chen

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16

Jinjun Cheng

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1 August 2017

31

Panduka Nagahawatte

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1 August 2017

Kathryn G Roberts

1

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1 August 2017

Yongjin Li

2

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1 August 2017

Yung-Li Yang

5

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1 August 2017

Li Ding

8

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1 August 2017

Charles Lu

9

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1 August 2017

Jing Ma

11

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1 August 2017

Natalia Santiago-Morales

18

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1 August 2017

Robert S Fulton

20

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1 August 2017

Ji Wen

21

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1 August 2017

Marcus Valentine

22

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1 August 2017

Cheng Cheng

23

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1 August 2017

I-Ming Chen

26

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1 August 2017

Amy Smith

28

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1 August 2017

Pankaj Gupta

30

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1 August 2017

Gang Wu

32

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1 August 2017

Xiang Chen

33

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1 August 2017

Eric C Larsen

38

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1 August 2017

William L Carroll

39

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1 August 2017

Andrew J Carroll

41

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1 August 2017

Guy Grayson

42

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1 August 2017

Melissa Frei-Jones

46

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1 August 2017

Timothy P Hughes

50

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1 August 2017

Jaime M Guidry Auvil

51

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1 August 2017

William E Evans

64

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Richard K Wilson

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James R Downing

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Jinghui Zhang

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1 August 2017

language of work or name

English

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publication date

1 September 2014

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The New England Journal of Medicine

1 August 2017

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1 August 2017

371

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1 August 2017

1005-1015

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1 August 2017

11

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Genomic characterization of childhood acute lymphoblastic leukemia

1 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191900

A recurrent germline PAX5 mutation confers susceptibility to pre-B cell acute lymphoblastic leukemia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191900

Independent prognostic value of BCR-ABL1-like signature and IKZF1 deletion, but not high CRLF2 expression, in children with B-cell precursor ALL.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191900

Role of ABL family kinases in cancer: from leukaemia to solid tumours

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191900

Tyrosine kinase inhibitor therapy induces remission in a patient with refractory EBF1-PDGFRB-positive acute lymphoblastic leukemia.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191900

Chaperones as thermodynamic sensors of drug-target interactions reveal kinase inhibitor specificities in living cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191900

Acute lymphoblastic leukaemia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191900

Tyrosine kinome sequencing of pediatric acute lymphoblastic leukemia: a report from the Children's Oncology Group TARGET Project

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191900

Targeting JAK1/2 and mTOR in murine xenograft models of Ph-like acute lymphoblastic leukemia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191900

Genetic alterations activating kinase and cytokine receptor signaling in high-risk acute lymphoblastic leukemia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191900

Aberrant STAT5 and PI3K/mTOR pathway signaling occurs in human CRLF2-rearranged B-precursor acute lymphoblastic leukemia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191900

Adolescents and young adults with acute lymphoblastic leukemia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191900

Rearrangement of CRLF2 is associated with mutation of JAK kinases, alteration of IKZF1, Hispanic/Latino ethnicity, and a poor outcome in pediatric B-progenitor acute lymphoblastic leukemia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191900

Rearrangement of CRLF2 in B-progenitor- and Down syndrome-associated acute lymphoblastic leukemia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191900

Improved early event-free survival with imatinib in Philadelphia chromosome-positive acute lymphoblastic leukemia: a children's oncology group study

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191900

A subtype of childhood acute lymphoblastic leukaemia with poor treatment outcome: a genome-wide classification study

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191900

Deletion of IKZF1 and prognosis in acute lymphoblastic leukemia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191900

Cytokine-dependent imatinib resistance in mouse BCR-ABL+, Arf-null lymphoblastic leukemia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191900

Arf gene loss enhances oncogenicity and limits imatinib response in mouse models of Bcr-Abl-induced acute lymphoblastic leukemia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191900

Macrophage colony-stimulating factor receptor c-fms is a novel target of imatinib.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191900

Expression of the ETV6-NTRK3 gene fusion as a primary event in human secretory breast carcinoma

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191900

A novel ETV6-NTRK3 gene fusion in congenital fibrosarcoma

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191900

A TEL-JAK2 fusion protein with constitutive kinase activity in human leukemia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191900

Evaluation of survival data and two new rank order statistics arising in its consideration

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191900

Successful tyrosine kinase inhibitor therapy in a refractory B-cell precursor acute lymphoblastic leukemia with EBF1-PDGFRB fusion

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191900

Identification of FOXP1 and SNX2 as novel ABL1 fusion partners in acute lymphoblastic leukaemia.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191900

Deregulated expression of cytokine receptor gene, CRLF2, is involved in lymphoid transformation in B-cell precursor acute lymphoblastic leukemia.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191900

BCR–ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191900

Fusion of ZMIZ1 to ABL1 in a B-cell acute lymphoblastic leukaemia with a t(9;10)(q34;q22.3) translocation

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191900

Absence of t(12;15) associatedETV6-NTRK3 fusion transcripts in pediatric acute leukemias

28 October 2018

1 reference

12 December 2020

Absence of t(12;15) associated ETV6-NTRK3 fusion transcripts in pediatric acute leukemias

1 reference

12 December 2020

ETV6-NTRK3 gene fusions and trisomy 11 establish a histogenetic link between mesoblastic nephroma and congenital fibrosarcoma

1 reference

12 December 2020

Novel SSBP2-JAK2 fusion gene resulting from a t(5;9)(q14.1;p24.1) in pre-B acute lymphocytic leukemia

1 reference

12 December 2020

Identifiers

DOI

10.1056/NEJMOA1403088

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1 August 2017

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1 August 2017

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