SUMOylation represses Nanog expression via modulating transcription factors Oct4 and Sox2 (Q34321578)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22745796%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

title

SUMOylation represses Nanog expression via modulating transcription factors Oct4 and Sox2 (English)

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6 February 2020

11

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author name string

Yongyan Wu

1

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6 February 2020

Zekun Guo

2

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6 February 2020

Haibo Wu

3

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6 February 2020

Xiaohai Wang

4

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6 February 2020

Lixia Yang

5

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6 February 2020

Xiaoyan Shi

6

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6 February 2020

Juan Du

7

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6 February 2020

Bo Tang

8

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6 February 2020

Wenzhong Li

9

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6 February 2020

Liping Yang

10

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6 February 2020

language of work or name

English

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publication date

22 June 2012

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6 February 2020

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6 February 2020

volume

7

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issue

6

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6 February 2020

page(s)

e39606

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Creative Commons Attribution 4.0 International

6 February 2020

copyright license

start time

22 June 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

SUMOylation of the Forkhead transcription factor FOXL2 promotes its stabilization/activation through transient recruitment to PML bodies

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Regulation of the Fanconi anemia pathway by a SUMO-like delivery network

6 July 2018

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SUMOylation of DEC1 protein regulates its transcriptional activity and enhances its stability

6 July 2018

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Nuclear organization in genome stability: SUMO connections

6 July 2018

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Sall1 regulates embryonic stem cell differentiation in association with nanog

6 July 2018

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Retracted: Ubiquitin/SUMO Modification Regulates VHL Protein Stability and Nucleocytoplasmic Localization

6 July 2018

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SUMOylation by Pias1 regulates the activity of the Hedgehog dependent Gli transcription factors

6 July 2018

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A small ubiquitin-related modifier-interacting motif functions as the transcriptional activation domain of Krüppel-like factor 4.

6 July 2018

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Sumoylation modulates the activity of Spalt-like proteins during wing development in Drosophila

6 July 2018

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An Oct4-centered protein interaction network in embryonic stem cells

6 July 2018

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SUMO--a post-translational modification with therapeutic potential?

6 July 2018

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Sumoylation regulates nuclear localization of lipin-1alpha in neuronal cells

6 July 2018

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Interplay of Oct4 with Sox2 and Sox17: a molecular switch from stem cell pluripotency to specifying a cardiac fate

6 July 2018

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Nanog is the gateway to the pluripotent ground state.

6 July 2018

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KLF4 and PBX1 directly regulate NANOG expression in human embryonic stem cells

6 July 2018

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Ginkgolic acid inhibits protein SUMOylation by blocking formation of the E1-SUMO intermediate

6 July 2018

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SUMO-specific protease 2 is essential for modulating p53-Mdm2 in development of trophoblast stem cell niches and lineages

6 July 2018

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Retinoic acid-stimulated sequential phosphorylation, PML recruitment, and SUMOylation of nuclear receptor TR2 to suppress Oct4 expression

6 July 2018

1 reference

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Developmental control of sumoylation pathway proteins in mouse male germ cells

6 July 2018

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Concepts in sumoylation: a decade on

6 July 2018

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The SUMO conjugating enzyme Ubc9 is a regulator of GLUT4 turnover and targeting to the insulin-responsive storage compartment in 3T3-L1 adipocytes

6 July 2018

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Sumoylation of nucleophosmin/B23 regulates its subcellular localization, mediating cell proliferation and survival

6 July 2018

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Sumoylation of Oct4 enhances its stability, DNA binding, and transactivation.

6 July 2018

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Pluripotency governed by Sox2 via regulation of Oct3/4 expression in mouse embryonic stem cells.

6 July 2018

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Post-translational modification of POU domain transcription factor Oct-4 by SUMO-1.

6 July 2018

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Sumoylation delays the ATF7 transcription factor subcellular localization and inhibits its transcriptional activity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382131

SUMO, the three Rs and cancer

6 July 2018

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Inhibition of DNA binding of Sox2 by the SUMO conjugation

6 July 2018

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Transcriptional dynamics of the embryonic stem cell switch

6 July 2018

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Modification of proteins by ubiquitin and ubiquitin-like proteins

6 July 2018

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Downregulation of NANOG induces differentiation of human embryonic stem cells to extraembryonic lineages

6 July 2018

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Transcriptional regulation of nanog by OCT4 and SOX2.

6 July 2018

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SUMO: a history of modification

6 July 2018

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A functional variant of SUMO4, a new I kappa B alpha modifier, is associated with type 1 diabetes

6 July 2018

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Protein modification by SUMO

6 July 2018

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Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells

6 July 2018

1 reference

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The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells

6 July 2018

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A new mathematical model for relative quantification in real-time RT-PCR

6 July 2018

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In vitro SUMO-1 modification requires two enzymatic steps, E1 and E2

6 July 2018

1 reference

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Establishment in culture of pluripotential cells from mouse embryos

6 July 2018

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Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells

6 July 2018

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Nanog expression in mouse germ cell development.

6 July 2018

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Octamer and Sox elements are required for transcriptional cis regulation of Nanog gene expression

21 January 2018

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Oct4 and Sox2 directly regulate expression of another pluripotency transcription factor, Zfp206, in embryonic stem cells.

21 January 2018

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Systematic study of protein sumoylation: Development of a site-specific predictor of SUMOsp 2.0

21 January 2018

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The Oct4 homologue PouV and Nanog regulate pluripotency in chicken embryonic stem cells

21 January 2018

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21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/22745796

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0039606

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6 February 2020

0 references

1 reference

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6 February 2020

PubMed publication ID

22745796

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22745796%20AND%20SRC:MED&resulttype=core&format=json