AID-targeting and hypermutation of non-immunoglobulin genes does not correlate with proximity to immunoglobulin genes in germinal center B cells (Q34328206)

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English	AID-targeting and hypermutation of non-immunoglobulin genes does not correlate with proximity to immunoglobulin genes in germinal center B cells	scientific article

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scholarly article

1 reference

Europe PubMed Central

1 August 2017

AID-targeting and hypermutation of non-immunoglobulin genes does not correlate with proximity to immunoglobulin genes in germinal center B cells (English)

1 reference

Europe PubMed Central

1 August 2017

author name string

Hillary Selle Gramlich

1

1 reference

Europe PubMed Central

1 August 2017

Tara Reisbig

2

1 reference

Europe PubMed Central

1 August 2017

David G Schatz

3

1 reference

Europe PubMed Central

1 August 2017

language of work or name

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publication date

29 June 2012

1 reference

Europe PubMed Central

1 August 2017

1 reference

Europe PubMed Central

1 August 2017

7

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Europe PubMed Central

1 August 2017

6

1 reference

Europe PubMed Central

1 August 2017

e39601

1 reference

Europe PubMed Central

1 August 2017

copyright license

Creative Commons Attribution 4.0 International

29 June 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

Spatial organization of the mouse genome and its role in recurrent chromosomal translocations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387148

6 July 2018

DNA damage defines sites of recurrent chromosomal translocations in B lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387148

6 July 2018

Genome-wide translocation sequencing reveals mechanisms of chromosome breaks and rearrangements in B cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387148

6 July 2018

Translocation-capture sequencing reveals the extent and nature of chromosomal rearrangements in B lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387148

6 July 2018

Epigenetic tethering of AID to the donor switch region during immunoglobulin class switch recombination.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387148

6 July 2018

AID: a riddle wrapped in a mystery inside an enigma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387148

6 July 2018

Deep-sequencing identification of the genomic targets of the cytidine deaminase AID and its cofactor RPA in B lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387148

6 July 2018

Comprehensive mapping of long-range interactions reveals folding principles of the human genome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387148

6 July 2018

Mechanisms promoting translocations in editing and switching peripheral B cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387148

6 July 2018

Balancing AID and DNA repair during somatic hypermutation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387148

6 July 2018

H3 trimethyl K9 and H3 acetyl K9 chromatin modifications are associated with class switch recombination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387148

6 July 2018

Chromosomal location targets different MYC family gene members for oncogenic translocations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387148

6 July 2018

AID is required for the chromosomal breaks in c-myc that lead to c-myc/IgH translocations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387148

6 July 2018

Analysis of intergenic transcription and histone modification across the human immunoglobulin heavy-chain locus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387148

6 July 2018

AID expression levels determine the extent of cMyc oncogenic translocations and the incidence of B cell tumor development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387148

6 July 2018

Association between the Igk and Igh immunoglobulin loci mediated by the 3' Igk enhancer induces 'decontraction' of the Igh locus in pre-B cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387148

6 July 2018

Germinal center structure and function: lessons from CD19

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387148

6 July 2018

Actin-dependent intranuclear repositioning of an active gene locus in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387148

6 July 2018

Myc dynamically and preferentially relocates to a transcription factory occupied by Igh

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387148

6 July 2018

Immunoglobulin somatic hypermutation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387148

6 July 2018

Molecular mechanisms of antibody somatic hypermutation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387148

6 July 2018

AID-dependent histone acetylation is detected in immunoglobulin S regions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387148

6 July 2018

Elucidation of IgH intronic enhancer functions via germ-line deletion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387148

6 July 2018

Complex regulation of somatic hypermutation by cis-acting sequences in the endogenous IgH gene in hybridoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387148

6 July 2018

Mismatch recognition and uracil excision provide complementary paths to both Ig switching and the A/T-focused phase of somatic mutation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387148

6 July 2018

Class-switch recombination: interplay of transcription, DNA deamination and DNA repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387148

6 July 2018

Chromatin decondensation and nuclear reorganization of the HoxB locus upon induction of transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387148

6 July 2018

AID-dependent generation of resected double-strand DNA breaks and recruitment of Rad52/Rad51 in somatic hypermutation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387148

6 July 2018

Somatic hypermutation of the B cell receptor genes B29 (Igbeta, CD79b) and mb1 (Igalpha, CD79a).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387148

6 July 2018

Transcriptional analysis of the B cell germinal center reaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387148

6 July 2018

Chromosome order in HeLa cells changes during mitosis and early G1, but is stably maintained during subsequent interphase stages.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387148

6 July 2018

Mechanisms of chromosomal translocations in B cell lymphomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387148

6 July 2018

Hypermutation of multiple proto-oncogenes in B-cell diffuse large-cell lymphomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387148

6 July 2018

Somatic mutation of the CD95 gene in human B cells as a side-effect of the germinal center reaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387148

6 July 2018

Cell-cycle-regulated DNA double-stranded breaks in somatic hypermutation of immunoglobulin genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387148

6 July 2018

Differences in the localization and morphology of chromosomes in the human nucleus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387148

6 July 2018

BCL-6 mutations in normal germinal center B cells: evidence of somatic hypermutation acting outside Ig loci

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387148

6 July 2018

Reevaluation of 3'Ekappa function in stage- and lineage-specific rearrangement and somatic hypermutation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387148

6 July 2018

Chromosomal translocations deregulating c-myc are associated with normal immune responses.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387148

6 July 2018

Targeting of non-Ig sequences in place of the V segment by somatic hypermutation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387148

6 July 2018

Mouse c-myc oncogene is located on chromosome 15 and translocated to chromosome 12 in plasmacytomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387148

6 July 2018

Translocation of the c-myc gene into the immunoglobulin heavy chain locus in human Burkitt lymphoma and murine plasmacytoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387148

6 July 2018

c-myc and immunoglobulin kappa light chain constant genes are on the 8q+ chromosome of three Burkitt lymphoma lines with t(2;8) translocations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387148

6 July 2018

Transcriptional activation of the translocated c-myc oncogene in burkitt lymphoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387148

6 July 2018

Translocations among antibody genes in human cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387148

6 July 2018

Transcriptionally active DNA region that rearranges frequently in murine lymphoid tumors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387148

6 July 2018

Transcriptionally active c- myc oncogene is contained within NIARD, a DNA sequence associated with chromosome translocations in B-cell neoplasia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387148

6 July 2018

N segment insertion and region-directed somatic hypermutation in a kappa gene of a t(2;8) chromosomal translocation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387148

6 July 2018

Generation of a variant t(2;8) translocation of Burkitt's lymphoma by site-specific recombination via the kappa light-chain joining signals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387148

6 July 2018

The t(8; 14) chromosomal translocation occurring in B-cell malignancies results from mistakes in V-D-J joining

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387148

6 July 2018

Burkitt lymphoma cell line carrying a variant translocation creates new DNA at the breakpoint and violates the hierarchy of immunoglobulin gene rearrangement

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387148

6 July 2018

Clonal recruitment and somatic mutation in the generation of immunological memory to the hapten NP

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387148

6 July 2018

Genetic recombination in a chromosomal translocation t(2;8)(p11;q24) of a Burkitt's lymphoma cell line, KOBK101.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387148

6 July 2018

Plasmacytomagenesis in mice: model of neoplastic development dependent upon chromosomal translocations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387148

6 July 2018

Analysis of the repertoire of anti-NP antibodies in C57BL/6 mice by cell fusion. I. Characterization of antibody families in the primary and hyperimmune response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387148

6 July 2018

Mutation of BCL-6 gene in normal B cells by the process of somatic hypermutation of Ig genes.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0039601

21 January 2018

Two levels of protection for the B cell genome during somatic hypermutation.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0039601

21 January 2018

Somatic hypermutation in the heavy chain locus correlates with transcription.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0039601

21 January 2018

Roles of the Ig kappa light chain intronic and 3' enhancers in Igk somatic hypermutation

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0039601

21 January 2018

Translocation, breakage and truncated transcripts of c-myc oncogene in murine plasmacytomas

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0039601

21 January 2018

A novel alteration in the structure of an activated c-myc gene in a variant t(2;8) Burkitt lymphoma.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0039601

21 January 2018

AID is required for c-myc/IgH chromosome translocations in vivo

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0039601

21 January 2018

In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0039601

21 January 2018

SATB1 regulates beta-like globin genes through matrix related nuclear relocation of the cluster.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0039601

21 January 2018

Chromatin motion is constrained by association with nuclear compartments in human cells.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0039601

21 January 2018

Definition of germinal-center B cell migration in vivo reveals predominant intrazonal circulation patterns.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0039601

21 January 2018

Imaging of germinal center selection events during affinity maturation

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0039601

21 January 2018

The TATA binding protein, c-Myc and survivin genes are not somatically hypermutated, while Ig and BCL6 genes are hypermutated in human memory B cells.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0039601

21 January 2018

DNA Double-Strand Breaks in Immunoglobulin Genes Undergoing Somatic Hypermutation

2 references

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0039601

21 January 2018

https://pubmed.ncbi.nlm.nih.gov/22768095

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice

2 references

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0039601

21 January 2018

https://pubmed.ncbi.nlm.nih.gov/22768095

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ig heavy chain class switching in Rag-deficient mice

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0039601

21 January 2018

The nuclear topography of ABL, BCR, PML, and RARalpha genes: evidence for gene proximity in specific phases of the cell cycle and stages of hematopoietic differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387148

27 October 2018

Variant translocations in sporadic Burkitt's lymphoma detected in fresh tumour material: analysis of three cases

1 reference

https://pubmed.ncbi.nlm.nih.gov/22768095

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proximity of chromosomal loci that participate in radiation-induced rearrangements in human cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22768095

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spatial proximity of translocation-prone gene loci in human lymphomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/22768095

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The E box motif CAGGTG enhances somatic hypermutation without enhancing transcription

1 reference

https://pubmed.ncbi.nlm.nih.gov/22768095

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elements regulating somatic hypermutation of an immunoglobulin κ gene: Critical role for the intron enhancer/matrix attachment region

1 reference

https://pubmed.ncbi.nlm.nih.gov/22768095

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Somatic hypermutation of immunoglobulin genes is linked to transcription initiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22768095

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Ig(kappa) enhancer influences the ratio of Ig(kappa) versus Ig(lambda) B lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22768095

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distribution of ABL and BCR genes in cell nuclei of normal and irradiated lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22768095

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of the role of the 3'alpha heavy chain enhancer [3'alpha E(hs1,2)] in Vh gene somatic hypermutation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22768095

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Histone modifications associated with somatic hypermutation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22768095

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0039601

1 reference

Europe PubMed Central

1 August 2017

2012PLoSO...739601G

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1 reference

Europe PubMed Central

1 August 2017

1 reference

Europe PubMed Central

1 August 2017

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