Polymorphic cytochrome P450 2D6: humanized mouse model and endogenous substrates. (Q34331552)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15237854%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

review article

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title

Polymorphic cytochrome P450 2D6: humanized mouse model and endogenous substrates (English)

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30 December 2019

2

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30 December 2019

author name string

Ai-Ming Yu

series ordinal

1

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30 December 2019

Frank J Gonzalez

series ordinal

3

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30 December 2019

language of work or name

English

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publication date

1 May 2004

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30 December 2019

published in

Drug Metabolism Reviews

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30 December 2019

volume

36

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30 December 2019

issue

2

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30 December 2019

page(s)

243-277

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Regulation of P450 genes by liver-enriched transcription factors and nuclear receptors

30 December 2019

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MPTP, the neurotoxin inducing Parkinson's disease, is a potent competitive inhibitor of human and rat cytochrome P450 isozymes (P450bufI, P450db1) catalyzing debrisoquine 4-hydroxylation.

21 January 2018

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The decreased in vivo clearance of CYP2D6 substrates by CYP2D6*10 might be caused not only by the low-expression but also by low affinity of CYP2D6.

21 January 2018

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Day-night rhythm of 5-methoxytryptamine biosynthesis in the pineal gland of the golden hamster (Mesocricetus auratus)

21 January 2018

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Cytochromes P450 mediating the N-demethylation of amitriptyline

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Characterization of (+/-)-bufuralol hydroxylation activities in liver microsomes of Japanese and Caucasian subjects genotyped for CYP2D6.

21 January 2018

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Cellular localization and regional distribution of CYP2D6 mRNA and protein expression in human brain

21 January 2018

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Metoprolol oxidation polymorphism in a Korean population: comparison with native Japanese and Chinese populations

21 January 2018

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Homologous unequal cross-over involving a 2.8 kb direct repeat as a mechanism for the generation of allelic variants of human cytochrome P450 CYP2D6 gene.

21 January 2018

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Development of a pharmacophore for inhibition of human liver cytochrome P-450 2D6: molecular modeling and inhibition studies

21 January 2018

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Analysis of imipramine and three metabolites produced by isozyme CYP2D6 expressed in a human cell line

21 January 2018

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Melatonin receptor pharmacology: toward subtype specificity

21 January 2018

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21 January 2018

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21 January 2018

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Science, medicine, and the future: Pharmacogenetics

21 January 2018

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The human CYP3A subfamily: practical considerations

21 January 2018

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The human drug metabolizing cytochromes P450.

21 January 2018

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Identification of human CYP isoforms involved in the metabolism of propranolol enantiomers--N-desisopropylation is mediated mainly by CYP1A2.

21 January 2018

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Expression, purification, biochemical characterization, and comparative function of human cytochrome P450 2D6.1, 2D6.2, 2D6.10, and 2D6.17 allelic isoforms

21 January 2018

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The relative contribution of monoamine oxidase and cytochrome p450 isozymes to the metabolic deamination of the trace amine tryptamine.

21 January 2018

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Regeneration of serotonin from 5-methoxytryptamine by polymorphic human CYP2D6.

21 January 2018

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Screening for endogenous substrates reveals that CYP2D6 is a 5-methoxyindolethylamine O-demethylase

21 January 2018

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Contribution of individual cytochrome P450 isozymes to the O-demethylation of the psychotropic beta-carboline alkaloids harmaline and harmine.

21 January 2018

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Codeine O-demethylation co-segregates with polymorphic debrisoquine hydroxylation

21 January 2018

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Comprehensive analysis of the genetic factors determining expression and function of hepatic CYP2D6.

21 January 2018

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Characterization of melatonin receptors in the brain of four avian species: duck, goose, pigeon, and turkey.

21 January 2018

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DEBRISOQUINE HYDROXYLATION PHENOTYPES IN HEALTHY VOLUNTEERS

21 January 2018

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Relationship between personality and debrisoquine hydroxylation capacity

21 January 2018

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Cytochrome P -450 activities in human and rat brain microsomes

21 January 2018

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Modulation of the age at onset of Parkinson's disease by apolipoprotein E genotypes

21 January 2018

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Genotyping of poor metabolisers of debrisoquine by allele-specific PCR amplification

21 January 2018

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The 5-hydroxytryptamine 5-HT1D receptor subtype is negatively coupled to adenylate cyclase in calf substantia nigra

21 January 2018

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21 January 2018

Identifiers

DOI

10.1081/DMR-120034000

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15237854%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

1 reference