The hippo tumor pathway promotes TAZ degradation by phosphorylating a phosphodegron and recruiting the SCF{beta}-TrCP E3 ligase. (Q34333492)

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14 February 2020

title

The hippo tumor pathway promotes TAZ degradation by phosphorylating a phosphodegron and recruiting the SCF{beta}-TrCP E3 ligase (English)

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14 February 2020

0 references

1

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14 February 2020

Qun-Ying Lei

13

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14 February 2020

author name string

Zheng-Yu Zha

2

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14 February 2020

Xin Zhou

3

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14 February 2020

Heng Zhang

4

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14 February 2020

Wei Huang

5

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14 February 2020

Di Zhao

6

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14 February 2020

Tingting Li

7

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14 February 2020

Siew Wee Chan

8

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14 February 2020

Chun Jye Lim

9

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14 February 2020

Wanjin Hong

10

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14 February 2020

Shimin Zhao

11

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14 February 2020

Yue Xiong

12

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14 February 2020

Kun-Liang Guan

14

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14 February 2020

language of work or name

English

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publication date

21 September 2010

1 reference

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Journal of Biological Chemistry

14 February 2020

published in

1 reference

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14 February 2020

volume

285

1 reference

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14 February 2020

issue

48

1 reference

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14 February 2020

page(s)

37159-37169

1 reference

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A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP)

14 February 2020

cites work

1 reference

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TEAD transcription factors mediate the function of TAZ in cell growth and epithelial-mesenchymal transition

6 July 2018

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TEADs mediate nuclear retention of TAZ to promote oncogenic transformation

6 July 2018

1 reference

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A role for TAZ in migration, invasion, and tumorigenesis of breast cancer cells

6 July 2018

1 reference

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TAZ promotes cell proliferation and epithelial-mesenchymal transition and is inhibited by the hippo pathway

6 July 2018

1 reference

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Multiple renal cysts, urinary concentration defects, and pulmonary emphysematous changes in mice lacking TAZ

6 July 2018

1 reference

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Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control

6 July 2018

1 reference

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TAZ promotes PC2 degradation through a SCFbeta-Trcp E3 ligase complex

6 July 2018

1 reference

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Filling out the Hippo pathway

6 July 2018

1 reference

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Hippo signaling in organ size control

6 July 2018

1 reference

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Mob as tumor suppressor is activated by Hippo kinase for growth inhibition in Drosophila

6 July 2018

1 reference

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The Salvador-Warts-Hippo pathway - an emerging tumour-suppressor network

6 July 2018

1 reference

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Glomerulocystic kidney disease in mice with a targeted inactivation of Wwtr1

6 July 2018

1 reference

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From cell structure to transcription: Hippo forges a new path

6 July 2018

1 reference

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TAZ: a beta-catenin-like molecule that regulates mesenchymal stem cell differentiation

6 July 2018

1 reference

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Defects in yolk sac vasculogenesis, chorioallantoic fusion, and embryonic axis elongation in mice with targeted disruption of Yap65

6 July 2018

1 reference

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The tumour-suppressor genes NF2/Merlin and Expanded act through Hippo signalling to regulate cell proliferation and apoptosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2988322

A WW domain protein TAZ is a critical coactivator for TBX5, a transcription factor implicated in Holt-Oram syndrome

6 July 2018

1 reference

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TAZ, a transcriptional modulator of mesenchymal stem cell differentiation

6 July 2018

1 reference

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The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP

6 July 2018

1 reference

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Control of cell proliferation and apoptosis by mob as tumor suppressor, mats

6 July 2018

1 reference

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The transcriptional co-activator TAZ interacts differentially with transcriptional enhancer factor-1 (TEF-1) family members

6 July 2018

1 reference

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TAZ interacts with TTF-1 and regulates expression of surfactant protein-C

6 July 2018

1 reference

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D4476, a cell-permeant inhibitor of CK1, suppresses the site-specific phosphorylation and nuclear exclusion of FOXO1a.

6 July 2018

1 reference

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hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts

6 July 2018

1 reference

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Structural basis for phosphodependent substrate selection and orientation by the SCFCdc4 ubiquitin ligase

6 July 2018

1 reference

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salvador Promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines

6 July 2018

1 reference

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Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism

6 July 2018

1 reference

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TAZ: a novel transcriptional co-activator regulated by interactions with 14-3-3 and PDZ domain proteins

6 July 2018

1 reference

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Positional syntenic cloning and functional characterization of the mammalian circadian mutation tau.

6 July 2018

1 reference

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Hippo promotes proliferation arrest and apoptosis in the Salvador/Warts pathway

6 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.152942

The fat cadherin acts through the hippo tumor-suppressor pathway to regulate tissue size.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.152942

The tumor-suppressor gene fat controls tissue growth upstream of expanded in the hippo signaling pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.152942

Fat cadherin modulates organ size in Drosophila via the Salvador/Warts/Hippo signaling pathway.

21 January 2018

1 reference

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IC261, a specific inhibitor of the protein kinases casein kinase 1-delta and -epsilon, triggers the mitotic checkpoint and induces p53-dependent postmitotic effects

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20858893

12 December 2020

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Identifiers

DOI

10.1074/JBC.M110.152942

1 reference

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Fatcat

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30 July 2022

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