Neuropilin-1 functions as a VEGFR2 co-receptor to guide developmental angiogenesis independent of ligand binding (Q34340832)

1 August 2017

Neuropilin-1 functions as a VEGFR2 co-receptor to guide developmental angiogenesis independent of ligand binding (English)

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1 August 2017

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5

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3 June 2020

Joyce Bischoff

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3 June 2020

author name string

Maria V Gelfand

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3 June 2020

Nellwyn Hagan

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3 June 2020

Aleksandra Tata

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3 June 2020

Won-Jong Oh

4

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3 June 2020

Kyu-Tae Kang

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3 June 2020

Justyna Kopycinska

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3 June 2020

Jia-Huai Wang

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3 June 2020

Chenghua Gu

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3 June 2020

language of work or name

English

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publication date

22 September 2014

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1 August 2017

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3 June 2020

volume

3

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3 June 2020

page(s)

e03720

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describes a project that uses

3 June 2020

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4197402/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Neuropilin 1 (NRP1) hypomorphism combined with defective VEGF-A binding reveals novel roles for NRP1 in developmental and pathological angiogenesis

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The neuropilin 1 cytoplasmic domain is required for VEGF-A-dependent arteriogenesis

6 July 2018

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Autocrine VEGF-VEGFR2-Neuropilin-1 signaling promotes glioma stem-like cell viability and tumor growth

6 July 2018

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The cytoplasmic domain of neuropilin 1 is dispensable for angiogenesis, but promotes the spatial separation of retinal arteries and veins

6 July 2018

1 reference

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Developmental and pathological angiogenesis

6 July 2018

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Semaphorin 3E-Plexin-D1 signaling regulates VEGF function in developmental angiogenesis via a feedback mechanism

6 July 2018

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VEGF binding to NRP1 is essential for VEGF stimulation of endothelial cell migration, complex formation between NRP1 and VEGFR2, and signaling via FAK Tyr407 phosphorylation

6 July 2018

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The binding of NCAM to FGFR1 induces a specific cellular response mediated by receptor trafficking

6 July 2018

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The original Pathologische Anatomie Leiden-Endothelium monoclonal antibody recognizes a vascular endothelial growth factor binding site within neuropilin-1.

6 July 2018

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Structural basis for ligand and heparin binding to neuropilin B domains

6 July 2018

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Blocking neuropilin-1 function has an additive effect with anti-VEGF to inhibit tumor growth

6 July 2018

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Glycosaminoglycan modification of neuropilin-1 modulates VEGFR2 signaling

6 July 2018

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VEGF receptor signalling - in control of vascular function

6 July 2018

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Endothelial cells and VEGF in vascular development

6 July 2018

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Soluble VEGF isoforms are essential for establishing epiphyseal vascularization and regulating chondrocyte development and survival

6 July 2018

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Vascular development and patterning: making the right choices

6 July 2018

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Neuropilin-1 conveys semaphorin and VEGF signaling during neural and cardiovascular development

6 July 2018

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The biology of VEGF and its receptors

6 July 2018

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Spatially restricted patterning cues provided by heparin-binding VEGF-A control blood vessel branching morphogenesis

6 July 2018

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Arteriolar and venular patterning in retinas of mice selectively expressing VEGF isoforms

6 July 2018

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Impaired myocardial angiogenesis and ischemic cardiomyopathy in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188

6 July 2018

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Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor

6 July 2018

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Neuropilin-semaphorin III/D-mediated chemorepulsive signals play a crucial role in peripheral nerve projection in mice.

6 July 2018

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6 July 2018

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Neuropilin is a receptor for the axonal chemorepellent Semaphorin III

6 July 2018

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6 July 2018

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6 July 2018

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Neuropilin-1 promotes VEGFR-2 trafficking through Rab11 vesicles thereby specifying signal output

6 July 2018

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Vascular endothelial growth factor regulates stanniocalcin-1 expression via neuropilin-1-dependent regulation of KDR and synergism with fibroblast growth factor-2.

21 January 2018

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21 January 2018

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A requirement for neuropilin-1 in embryonic vessel formation.

21 January 2018

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12 December 2020

based on heuristic

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inferred from PubMed ID database lookup

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based on heuristic

Identifiers

DOI

10.7554/ELIFE.03720

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25244320%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25244320%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

1 reference

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