Protein phosphatase 4 interacts with and down-regulates insulin receptor substrate 4 following tumor necrosis factor-alpha stimulation (Q34343619)

1 August 2017

Protein phosphatase 4 interacts with and down-regulates insulin receptor substrate 4 following tumor necrosis factor-alpha stimulation (English)

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Kathie A Mihindukulasuriya

1 August 2017

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object named as

Kathie A Mihindukulasuriya

1

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author name string

Guisheng Zhou

2

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1 August 2017

Jun Qin

3

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1 August 2017

Tse-Hua Tan

4

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1 August 2017

language of work or name

English

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publication date

24 August 2004

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Journal of Biological Chemistry

1 August 2017

7

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based on heuristic

inferred from page(s)

published in

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1 August 2017

279

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1 August 2017

45

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1 August 2017

46588-46594

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Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein

1 August 2017

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Role of IRS-2 in insulin and cytokine signalling

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The 60-kDa phosphotyrosine protein in insulin-treated adipocytes is a new member of the insulin receptor substrate family.

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A novel 160-kDa phosphotyrosine protein in insulin-treated embryonic kidney cells is a new member of the insulin receptor substrate family

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Two New Substrates in Insulin Signaling, IRS5/DOK4 and IRS6/DOK5

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The IRS-signalling system: a network of docking proteins that mediate insulin action

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Insulin receptor substrate (IRS) transduction system: distinct and overlapping signaling potential

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Protein-protein interaction in insulin signaling and the molecular mechanisms of insulin resistance

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Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene.

21 January 2018

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Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1.

21 January 2018

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Disruption of IRS-2 causes type 2 diabetes in mice

21 January 2018

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Insulin receptor substrate 3 is not essential for growth or glucose homeostasis.

21 January 2018

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Characterization of insulin receptor substrate 4 in human embryonic kidney 293 cells

21 January 2018

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Interplay of the proto-oncogene proteins CrkL and CrkII in insulin-like growth factor-I receptor-mediated signal transduction

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The Insulin-Like Growth Factor I Receptor-Induced Interaction of Insulin Receptor Substrate-4 and Crk-II

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Insulin receptor substrate-4 enhances insulin-like growth factor-I-induced cell proliferation

21 January 2018

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Insulin receptor substrate 4 supports insulin- and interleukin 4-stimulated proliferation of hematopoietic cells

21 January 2018

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IRS-4 mediated mitogenic signalling by insulin and growth hormone in LB cells, a murine T-cell lymphoma devoid of IGF-I receptors

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Hepatocyte growth factor stimulates proliferation of pancreatic beta-cells particularly in the presence of subphysiological glucose concentrations

21 January 2018

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Insulin receptor substrate-4 signaling in quiescent rat hepatocytes and in regenerating rat liver.

21 January 2018

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Selective alterations in insulin receptor substrates-1, -2 and -4 in theca but not granulosa cells from polycystic ovaries

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Differential roles of insulin receptor substrates in brown adipocyte differentiation

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Decreasing IRS-2 expression in pancreatic β-cells (INS-1) promotes apoptosis, which can be compensated for by introduction of IRS-4 expression

21 January 2018

1 reference

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Insulin receptor substrate 3 (IRS-3) and IRS-4 impair IRS-1- and IRS-2-mediated signaling

21 January 2018

1 reference

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Insulin receptor substrate-4 is expressed in muscle tissue without acting as a substrate for the insulin receptor

21 January 2018

1 reference

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Defects of the insulin receptor substrate (IRS) system in human metabolic disorders

21 January 2018

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Insulin receptor substrate 4 associates with the protein IRAS

21 January 2018

1 reference

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SOCS-6 binds to insulin receptor substrate 4, and mice lacking the SOCS-6 gene exhibit mild growth retardation

21 January 2018

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Protein phosphatase X has been highly conserved during mammalian evolution

21 January 2018

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Alpha 4 associates with protein phosphatases 2A, 4, and 6

21 January 2018

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Alpha4 protein as a common regulator of type 2A-related serine/threonine protein phosphatases

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Purification and identification of a novel subunit of protein serine/threonine phosphatase 4

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Okadaic acid: the archetypal serine/threonine protein phosphatase inhibitor

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Protein phosphatase X interacts with c-Rel and stimulates c-Rel/nuclear factor kappaB activity

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Suppression of MEK/ERK signaling pathway enhances cisplatin-induced NF-kappaB activation by protein phosphatase 4-mediated NF-kappaB p65 Thr dephosphorylation

21 January 2018

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Protein phosphatase 4 is involved in tumor necrosis factor-alpha-induced activation of c-Jun N-terminal kinase

21 January 2018

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Protein phosphatase 4 interacts with the Survival of Motor Neurons complex and enhances the temporal localisation of snRNPs

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Genomic structure of the mouse PP4 gene: a developmentally regulated protein phosphatase

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Interaction of hematopoietic progenitor kinase 1 with adapter proteins Crk and CrkL leads to synergistic activation of c-Jun N-terminal kinase

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Stable histone deacetylase complexes distinguished by the presence of SANT domain proteins CoREST/kiaa0071 and Mta-L1

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Regulation of SRC-3 (pCIP/ACTR/AIB-1/RAC-3/TRAM-1) Coactivator activity by I kappa B kinase

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Tumour necrosis factor alpha: a key regulator of adipose tissue mass

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Tumor necrosis factor alpha produces insulin resistance in skeletal muscle by activation of inhibitor kappaB kinase in a p38 MAPK-dependent manner

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The c-Jun NH(2)-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser(307)

21 January 2018

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Serine phosphorylation of insulin receptor substrate 1 by inhibitor kappa B kinase complex.

21 January 2018

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The role of TNFalpha and TNF receptors in obesity and insulin resistance

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Molecular mechanisms of insulin receptor substrate protein-mediated modulation of insulin signalling

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Molecular mechanism of insulin-induced degradation of insulin receptor substrate 1

21 January 2018

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Tumor necrosis factor-alpha-induced insulin resistance in 3T3-L1 adipocytes is accompanied by a loss of insulin receptor substrate-1 and GLUT4 expression without a loss of insulin receptor-mediated signal transduction.

21 January 2018

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Pioglitazone ameliorates tumor necrosis factor-alpha-induced insulin resistance by a mechanism independent of adipogenic activity of peroxisome proliferator--activated receptor-gamma

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RETRACTED: A new mechanism of neurodegeneration: a proinflammatory cytokine inhibits receptor signaling by a survival peptide

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Cytokine-hormone interactions: tumor necrosis factor alpha impairs biologic activity and downstream activation signals of the insulin-like growth factor I receptor in myoblasts

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Nutrient-dependent and insulin-stimulated phosphorylation of insulin receptor substrate-1 on serine 302 correlates with increased insulin signaling

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Positive and negative regulatory role of insulin receptor substrate 1 and 2 (IRS-1 and IRS-2) serine/threonine phosphorylation.

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A novel 50 kDa protein forms complexes with protein phosphatase 4 and is located at centrosomal microtubule organizing centres

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21 January 2018

Identifiers

DOI

10.1074/JBC.M408067200

1 reference

1 August 2017

1 reference