Sortilin-mediated endocytosis determines levels of the frontotemporal dementia protein, progranulin. (Q34346014)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21092856%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

title

Sortilin-mediated endocytosis determines levels of the frontotemporal dementia protein, progranulin (English)

1 reference

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16 January 2020

0 references

1 reference

GOA release 2020-03-11

Sortilin 1

1 reference

GOA release 2020-03-11

endocytosis

1 reference

GOA release 2020-03-11

frontotemporal dementia

1 reference

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21092856%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Anders Nykjaer

8

1 reference

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16 January 2020

Stephen M. Strittmatter

9

1 reference

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16 January 2020

author name string

Fenghua Hu

1

1 reference

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16 January 2020

Thihan Padukkavidana

2

1 reference

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16 January 2020

Christian B Vægter

3

1 reference

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16 January 2020

Owen A Brady

4

1 reference

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16 January 2020

Yanqiu Zheng

5

1 reference

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16 January 2020

Ian R Mackenzie

6

1 reference

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16 January 2020

language of work or name

English

0 references

publication date

1 November 2010

1 reference

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16 January 2020

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16 January 2020

volume

68

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16 January 2020

issue

4

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16 January 2020

page(s)

654-667

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Accelerated lipofuscinosis and ubiquitination in granulin knockout mice suggest a role for progranulin in successful aging

16 January 2020

cites work

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Exaggerated inflammation, impaired host defense, and neuropathology in progranulin-deficient mice

6 July 2018

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Valosin-containing protein (VCP) is required for autophagy and is disrupted in VCP disease

6 July 2018

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6 July 2018

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Progranulin is expressed within motor neurons and promotes neuronal cell survival

6 July 2018

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Synergistic effect between proteasome and autophagosome in the clearance of polyubiquitinated TDP-43.

6 July 2018

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The inactivation of the sortilin gene leads to a partial disruption of prosaposin trafficking to the lysosomes

6 July 2018

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Rapamycin rescues TDP-43 mislocalization and the associated low molecular mass neurofilament instability

6 July 2018

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6 July 2018

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Cellular prion protein mediates impairment of synaptic plasticity by amyloid-beta oligomers

6 July 2018

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Plasma progranulin levels predict progranulin mutation status in frontotemporal dementia patients and asymptomatic family members

6 July 2018

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Ligands bind to Sortilin in the tunnel of a ten-bladed beta-propeller domain

6 July 2018

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Nomenclature for neuropathologic subtypes of frontotemporal lobar degeneration: consensus recommendations

6 July 2018

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VPS10P-domain receptors - regulators of neuronal viability and function.

6 July 2018

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Low plasma progranulin levels predict progranulin mutations in frontotemporal lobar degeneration.

6 July 2018

1 reference

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Sortilin mediates the lysosomal targeting of cathepsins D and H

6 July 2018

1 reference

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Progranulin functions as a neurotrophic factor to regulate neurite outgrowth and enhance neuronal survival

6 July 2018

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TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis

6 July 2018

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TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis

6 July 2018

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Neuropathologic diagnostic and nosologic criteria for frontotemporal lobar degeneration: consensus of the Consortium for Frontotemporal Lobar Degeneration

6 July 2018

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The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease

6 July 2018

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Pro-NGF secreted by astrocytes promotes motor neuron cell death

6 July 2018

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Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

6 July 2018

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Mutations in progranulin are a major cause of ubiquitin-positive frontotemporal lobar degeneration

6 July 2018

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Sortilin, SorCS1b, and SorLA Vps10p sorting receptors, are novel gamma-secretase substrates

6 July 2018

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Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17

6 July 2018

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Null mutations in progranulin cause ubiquitin-positive frontotemporal dementia linked to chromosome 17q21

6 July 2018

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Tumour necrosis factor alpha-converting enzyme mediates ectodomain shedding of Vps10p-domain receptor family members

6 July 2018

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Neuronal sorting protein-related receptor sorLA/LR11 regulates processing of the amyloid precursor protein

6 July 2018

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ProBDNF induces neuronal apoptosis via activation of a receptor complex of p75NTR and sortilin.

6 July 2018

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6 July 2018

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Inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia is caused by mutant valosin-containing protein

6 July 2018

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Sortilin is essential for proNGF-induced neuronal cell death

6 July 2018

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The lysosomal trafficking of sphingolipid activator proteins (SAPs) is mediated by sortilin

6 July 2018

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6 July 2018

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Progranulin is a mediator of the wound response

6 July 2018

1 reference

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The sortilin cytoplasmic tail conveys Golgi-endosome transport and binds the VHS domain of the GGA2 sorting protein

6 July 2018

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Identification of a receptor mediating Nogo-66 inhibition of axonal regeneration

6 July 2018

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Vps10p cycles between the late-Golgi and prevacuolar compartments in its function as the sorting receptor for multiple yeast vacuolar hydrolases.

6 July 2018

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Transgenic mice expressing mutant forms VCP/p97 recapitulate the full spectrum of IBMPFD including degeneration in muscle, brain and bone.

6 July 2018

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Axonal ligation induces transient redistribution of TDP-43 in brainstem motor neurons

27 October 2018

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Serum biomarker for progranulin-associated frontotemporal lobar degeneration

27 October 2018

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Roles for the pro-neurotrophin receptor sortilin in neuronal development, aging and brain injury

27 October 2018

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Alteration of behavioural phenotype in mice by targeted disruption of the progranulin gene.

27 October 2018

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The neuropathology of frontotemporal lobar degeneration caused by mutations in the progranulin gene.

27 October 2018

1 reference

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Divergent patterns of cytosolic TDP-43 and neuronal progranulin expression following axotomy: implications for TDP-43 in the physiological response to neuronal injury

27 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21092856

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The lysosomal trafficking of acid sphingomyelinase is mediated by sortilin and mannose 6-phosphate receptor

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21092856

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.NEURON.2010.09.034

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21092856%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21092856%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

1 reference