The sigma-1 receptor chaperone as an inter-organelle signaling modulator (Q34356970)

1 August 2017

title

The sigma-1 receptor chaperone as an inter-organelle signaling modulator (English)

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1 August 2017

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4

Shilpa Buch

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1 August 2017

Tsung-Ping Su

1

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1 August 2017

Teruo Hayashi

series ordinal

2

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1 August 2017

Tangui Maurice

series ordinal

3

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1 August 2017

Arnold E Ruoho

series ordinal

5

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1 August 2017

publication date

1 October 2010

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Trends in Pharmacological Sciences

1 August 2017

published in

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1 August 2017

volume

31

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1 August 2017

issue

12

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1 August 2017

page(s)

557-566

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Essential regulation of cell bioenergetics by constitutive InsP3 receptor Ca2+ transfer to mitochondria.

1 August 2017

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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When the endogenous hallucinogenic trace amine N,N-dimethyltryptamine meets the sigma-1 receptor

6 July 2018

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The hallucinogen N,N-dimethyltryptamine (DMT) is an endogenous sigma-1 receptor regulator

6 July 2018

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Probing the steroid binding domain-like I (SBDLI) of the sigma-1 receptor binding site using N-substituted photoaffinity labels.

6 July 2018

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Juxtaposition of the steroid binding domain-like I and II regions constitutes a ligand binding site in the sigma-1 receptor

6 July 2018

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The sigma receptor: evolution of the concept in neuropsychopharmacology

6 July 2018

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Sigma-1 receptor chaperones at the ER-mitochondrion interface regulate Ca(2+) signaling and cell survival

6 July 2018

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Ligand-dependent localization and intracellular stability of sigma-1 receptors in CHO-K1 cells

6 July 2018

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The sigma-1 receptor modulates NMDA receptor synaptic transmission and plasticity via SK channels in rat hippocampus.

6 July 2018

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The anti-amnesic and neuroprotective effects of donepezil against amyloid beta25-35 peptide-induced toxicity in mice involve an interaction with the sigma1 receptor

6 July 2018

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Sigma-1 receptor activation prevents intracellular calcium dysregulation in cortical neurons during in vitro ischemia

6 July 2018

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Purification and characterization of the guinea pig sigma-1 receptor functionally expressed in Escherichia coli

6 July 2018

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Pharmacophore identification for sigma-1 (sigma1) receptor binding: application of the "deconstruction-reconstruction-elaboration" approach

6 July 2018

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Involvement of sigma (sigma) receptors in the acute actions of methamphetamine: receptor binding and behavioral studies

6 July 2018

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sigma Receptor activation blocks potassium channels and depresses neuroexcitability in rat intracardiac neurons

6 July 2018

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Expression of sigma 1 receptor in human breast cancer

6 July 2018

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Sigma-1 receptors at galactosylceramide-enriched lipid microdomains regulate oligodendrocyte differentiation

6 July 2018

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Small molecule antagonists of the sigma-1 receptor cause selective release of the death program in tumor and self-reliant cells and inhibit tumor growth in vitro and in vivo

6 July 2018

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Generation and phenotypic analysis of sigma receptor type I (σ1) knockout mice

6 July 2018

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Protein kinase C-dependent potentiation of intracellular calcium influx by sigma1 receptor agonists in rat hippocampal neurons.

6 July 2018

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SR31747A is a sigma receptor ligand exhibiting antitumoural activity both in vitro and in vivo

6 July 2018

1 reference

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Antagonism of NMDA receptors by sigma receptor ligands attenuates chemical ischemia-induced neuronal death in vitro

6 July 2018

1 reference

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Expression pattern of the type 1 sigma receptor in the brain and identity of critical anionic amino acid residues in the ligand-binding domain of the receptor

6 July 2018

1 reference

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Regulating ankyrin dynamics: Roles of sigma-1 receptors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993063

sigma(1)-receptor ligand 4-phenyl-1-(4-phenylbutyl)-piperidine affords neuroprotection from focal ischemia with prolonged reperfusion

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993063

Sigma receptor photolabeling and sigma receptor-mediated modulation of potassium channels in tumor cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993063

A-Current down-modulated by sigma receptor in frog pituitary melanotrope cells through a G protein-dependent pathway.

6 July 2018

1 reference

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Molecular and ligand-binding characterization of the sigma-receptor in the Jurkat human T lymphocyte cell line

6 July 2018

1 reference

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Amino acid residues in the transmembrane domain of the type 1 sigma receptor critical for ligand binding

6 July 2018

1 reference

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Cloning and functional characterization of a sigma receptor from rat brain.

6 July 2018

1 reference

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Exon-intron structure, analysis of promoter region, and chromosomal localization of the human type 1 sigma receptor gene

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993063

Purification and characterization of the human SR 31747A-binding protein. A nuclear membrane protein related to yeast sterol isomerase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993063

High affinity of sigma 1-binding sites for sterol isomerization inhibitors: evidence for a pharmacological relationship with the yeast sterol C8-C7 isomerase

6 July 2018

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Yeast sterol C8-C7 isomerase: identification and characterization of a high-affinity binding site for enzyme inhibitors

6 July 2018

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Cloning and functional expression of the human type 1 sigma receptor (hSigmaR1)

6 July 2018

1 reference

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Interactions of selective serotonin reuptake inhibitors with subtypes of sigma receptors in rat brain

6 July 2018

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Emopamil-binding protein, a mammalian protein that binds a series of structurally diverse neuroprotective agents, exhibits delta8-delta7 sterol isomerase activity in yeast

6 July 2018

1 reference

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Purification, molecular cloning, and expression of the mammalian sigma1-binding site

6 July 2018

1 reference

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Characterization of two novel sigma receptor ligands: antidystonic effects in rats suggest sigma receptor antagonism

6 July 2018

1 reference

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A unique mitochondria-associated membrane fraction from rat liver has a high capacity for lipid synthesis and contains pre-Golgi secretory proteins including nascent lipoproteins

6 July 2018

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Naloxone-inaccessible sigma receptor in rat central nervous system

6 July 2018

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Sigma opiates and certain antipsychotic drugs mutually inhibit (+)-[3H] SKF 10,047 and [3H]haloperidol binding in guinea pig brain membranes

6 July 2018

1 reference

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Interactions of metaphit with phencyclidine and sigma agonist actions in rat cerebellum: determination of specificity and selectivity

6 July 2018

1 reference

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1,3-Di(2-[5-3H]tolyl)guanidine: a selective ligand that labels sigma-type receptors for psychotomimetic opiates and antipsychotic drugs

6 July 2018

1 reference

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Evidence that the potential antipsychotic agent rimcazole (BW 234U) is a specific, competitive antagonist of sigma sites in brain

6 July 2018

1 reference

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Cocaine binding at sigma receptors.

6 July 2018

1 reference

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Steroid binding at sigma receptors suggests a link between endocrine, nervous, and immune systems

6 July 2018

1 reference

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Receptor mechanisms in antipsychotic drug action: focus on sigma receptors

6 July 2018

1 reference

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Synthesis and evaluation of optically pure [3H]-(+)-pentazocine, a highly potent and selective radioligand for sigma receptors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993063

Alterations in the stereochemistry of the kappa-selective opioid agonist U50,488 result in high-affinity sigma ligands

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993063

N-methyl-D-aspartate-induced neuronal activation is selectively modulated by sigma receptors

6 July 2018

1 reference

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The molecular pathology of Alzheimer's disease

6 July 2018

1 reference

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Sigma compounds derived from phencyclidine: identification of PRE-084, a new, selective sigma ligand

6 July 2018

1 reference

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Anti-amnesic and neuroprotective potentials of the mixed muscarinic receptor/sigma1 (σ1) ligand ANAVEX2-73, a novel aminotetrahydrofuran derivative

6 July 2018

1 reference

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Effects of dextromethorphan/quinidine on auditory event-related potentials in multiple sclerosis patients with pseudobulbar affect

27 October 2018

1 reference

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Antiamnesic and neuroprotective effects of the aminotetrahydrofuran derivative ANAVEX1-41 against amyloid beta(25-35)-induced toxicity in mice

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993063

Dimemorfan protects rats against ischemic stroke through activation of sigma-1 receptor-mediated mechanisms by decreasing glutamate accumulation

27 October 2018

1 reference

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Sigma-1 receptors bind cholesterol and remodel lipid rafts in breast cancer cell lines

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993063

Characterization of the cocaine binding site on the sigma-1 receptor

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993063

Sigma receptor activation reduces infarct size at 24 hours after permanent middle cerebral artery occlusion in rats

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993063

Cocaine-induced HIV-1 expression in microglia involves sigma-1 receptors and transforming growth factor-beta1.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993063

Chronic antidepressants potentiate via sigma-1 receptors the brain-derived neurotrophic factor-induced signaling for glutamate release

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993063

A variant of the sigma receptor type-1 gene is a protective factor for Alzheimer disease.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993063

Cocaine and sigma-1 receptors modulate HIV infection, chemokine receptors, and the HPA axis in the huPBL-SCID model

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993063

Compensatory effect by sigma1 (sigma1) receptor stimulation during alcohol withdrawal in mice performing an object recognition task

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993063

Neuroprotective effects of sigma-1 receptor agonists against beta-amyloid-induced toxicity.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993063

Sulfhydryl-reactive, cleavable, and radioiodinatable benzophenone photoprobes for study of protein-protein interaction

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993063

Intracellular Dynamics of σ-1 Receptors (σ1Binding Sites) in NG108-15 Cells

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993063

σ-1 Receptors (σ1Binding Sites) Form Raft-Like Microdomains and Target Lipid Droplets on the Endoplasmic Reticulum: Roles in Endoplasmic Reticulum Lipid Compartmentalization and Export

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993063

Spreading depression: imaging and blockade in the rat neocortical brain slice

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993063

Sigma receptors inhibit high-voltage-activated calcium channels in rat sympathetic and parasympathetic neurons

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993063

The sigma receptor as a ligand-regulated auxiliary potassium channel subunit

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993063

Neuroprotective effect of sigma(1)-receptor ligand 4-phenyl-1-(4-phenylbutyl) piperidine (PPBP) is linked to reduced neuronal nitric oxide production

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993063

Molecular cloning and pharmacological characterization of the rat sigma1 receptor

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993063

The sigma-ligand (+)-pentazocine depresses M current and enhances calcium conductances in frog melanotrophs

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993063

Sigma1 (sigma 1) receptor agonists and neurosteroids attenuate B25-35-amyloid peptide-induced amnesia in mice through a common mechanism.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993063

Structural features important for sigma 1 receptor binding

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993063

[3H](+)-pentazocine binding to rat brain sigma 1 receptors

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993063

Behavioral evidence for a modulating role of sigma ligands in memory processes. I. Attenuation of dizocilpine (MK-801)-induced amnesia

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993063

Sigma-1 and sigma-2 sites in rat brain: comparison of regional, ontogenetic, and subcellular patterns

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993063

NE-100, a novel sigma receptor ligand: in vivo tests

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993063

Cytotoxic effects of sigma ligands: sigma receptor-mediated alterations in cellular morphology and viability.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993063

Effect of NE-100, a novel sigma receptor ligand, on phencyclidine-induced delayed cognitive dysfunction in rats

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993063

Modulation by sigma ligands of intracellular free Ca++ mobilization by N-methyl-D-aspartate in primary culture of rat frontal cortical neurons

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993063

(+)-[3H]SKF 10,047, (+)-[3H]ethylketocyclazocine, mu, kappa, delta and phencyclidine binding sites in guinea pig brain membranes

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993063

Inhibition of potassium currents by the sigma receptor ligand (+)-3-(3-hydroxyphenyl)-N-(1-propyl)piperidine in sympathetic neurons of the mouse isolated hypogastric ganglion.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993063

H1 antihistamines interact with central sigma receptors

27 October 2018

1 reference

12 December 2020

Immunopharmacological profile of SR 31747: in vitro and in vivo studies on humoral and cellular responses

1 reference

12 December 2020

Is a nitrogen atom an important pharmacophoric element in sigma ligand binding?

1 reference

12 December 2020

A proposal for the classification of sigma binding sites

1 reference

12 December 2020

2-Receptor Ligand-Mediated Inhibition of Inwardly Rectifying K+ Channels in the Heart

1 reference

12 December 2020

Ca(2+) signaling via sigma(1)-receptors: novel regulatory mechanism affecting intracellular Ca(2+) concentration

1 reference

12 December 2020

Identification of regions of the sigma-1 receptor ligand binding site using a novel photoprobe

1 reference

12 December 2020

10.1016/J.TIPS.2010.08.007

Identifiers

DOI

1 reference

1 August 2017

1 reference

1 August 2017

1 reference