Insulin and hypoxia share common target genes but not the hypoxia-inducible factor-1alpha (Q42799057)

7 November 2017

Insulin and hypoxia share common target genes but not the hypoxia-inducible factor-1alpha (English)

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7 November 2017

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Sujin Yim

1

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7 November 2017

Su Mi Choi

2

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7 November 2017

Youngyeon Choi

3

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7 November 2017

Naery Lee

4

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7 November 2017

Jieun Chung

5

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7 November 2017

Hyunsung Park

6

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7 November 2017

language of work or name

English

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publication date

21 July 2003

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Journal of Biological Chemistry

7 November 2017

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7 November 2017

278

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7 November 2017

40

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7 November 2017

38260-38268

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A conserved family of prolyl-4-hydroxylases that modify HIF

7 November 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306016200

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306016200

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306016200

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306016200

Control of cell lineage-specific development and transcription by bHLH-PAS proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306016200

Activation of protein kinase B/Akt is sufficient to repress the glucocorticoid and cAMP induction of phosphoenolpyruvate carboxykinase gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306016200

Insulin and insulin-like growth factor-I induce vascular endothelial growth factor mRNA expression via different signaling pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306016200

Insulin regulates transcription of the CCAAT/enhancer binding protein (C/EBP) alpha, beta, and delta genes in fully-differentiated 3T3-L1 adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306016200

Molecular regulation of the endothelin-1 gene by hypoxia. Contributions of hypoxia-inducible factor-1, activator protein-1, GATA-2, AND p300/CBP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306016200

Insulin induces transcription of target genes through the hypoxia-inducible factor HIF-1alpha/ARNT

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306016200

Transcription factor HIF-1 is a necessary mediator of the pasteur effect in mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306016200

Glucose regulation of gene transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306016200

A novel bHLH-PAS factor with close sequence similarity to hypoxia-inducible factor 1alpha regulates the VEGF expression and is potentially involved in lung and vascular development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306016200

1-Phosphatidylinositol 3-kinase activity is required for insulin-stimulated glucose transport but not for RAS activation in CHO cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306016200

Dioxin-induced CYP1A1 transcription in vivo: the aromatic hydrocarbon receptor mediates transactivation, enhancer-promoter communication, and changes in chromatin structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306016200

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306016200

HIF-1alpha binding to VHL is regulated by stimulus-sensitive proline hydroxylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306016200

Signalling through the lipid products of phosphoinositide-3-OH kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306016200

Insulin stimulation of the fatty acid synthase promoter is mediated by the phosphatidylinositol 3-kinase pathway. Involvement of protein kinase B/Akt

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306016200

Antagonistic effects of different members of the fibroblast and platelet-derived growth factor families on adipose conversion and NADPH-dependent H2O2 generation in 3T3 L1-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306016200

Reactive oxygen species generated at mitochondrial complex III stabilize hypoxia-inducible factor-1alpha during hypoxia: a mechanism of O2 sensing

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306016200

Oxygen sensing and HIF-1 activation does not require an active mitochondrial respiratory chain electron-transfer pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306016200

Insulin stimulates hypoxia-inducible factor 1 through a phosphatidylinositol 3-kinase/target of rapamycin-dependent signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306016200

Lack of evidence for the involvement of the phosphoinositide 3-kinase/Akt pathway in the activation of hypoxia-inducible factors by low oxygen tension.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306016200

Phosphatidylinositol 3-kinase/Akt signaling is neither required for hypoxic stabilization of HIF-1 alpha nor sufficient for HIF-1-dependent target gene transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306016200

Regulation of GLUT1 gene transcription by the serine/threonine kinase Akt1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306016200

Induction of HIF-1alpha in response to hypoxia is instantaneous

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306016200

Nutritional and insulin regulation of fatty acid synthetase and leptin gene expression through ADD1/SREBP1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306016200

Sterol regulatory element-binding proteins (SREBPs): key regulators of nutritional homeostasis and insulin action

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306016200

Inhibition of PPAR gamma 2 gene expression by the HIF-1-regulated gene DEC1/Stra13: a mechanism for regulation of adipogenesis by hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306016200

Hypoxia-inducible factor 1-mediated inhibition of peroxisome proliferator-activated receptor alpha expression during hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306016200

Inhibitory PAS domain protein is a negative regulator of hypoxia-inducible gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306016200

DNA binding specificities and pairing rules of the Ah receptor, ARNT, and SIM proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306016200

Hypoxia-inducible mammalian gene expression analyzed in vivo at a TATA-driven promoter and at an initiator-driven promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306016200

The PAS domain confers target gene specificity of Drosophila bHLH/PAS proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306016200

A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306016200

21 January 2018

Identifiers

DOI

10.1074/JBC.M306016200

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7 November 2017

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