Schistosoma mansoni triggers Dectin-2, which activates the Nlrp3 inflammasome and alters adaptive immune responses (Q34377258)

1 August 2017

title

Schistosoma mansoni triggers Dectin-2, which activates the Nlrp3 inflammasome and alters adaptive immune responses (English)

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1 August 2017

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7

Jürg Tschopp

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1 August 2017

8

Laura E Layland

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Clarissa Prazeres da Costa

1 August 2017

9

object named as

Clarissa Prazeres da Costa

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1 August 2017

Manuel Ritter

1

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1 August 2017

Olaf Gross

2

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1 August 2017

Sarah Kays

3

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1 August 2017

Jürgen Ruland

4

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1 August 2017

Falk Nimmerjahn

5

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1 August 2017

Shinobu Saijo

6

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1 August 2017

language of work or name

English

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publication date

8 November 2010

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Proceedings of the National Academy of Sciences of the United States of America

1 August 2017

published in

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1 August 2017

volume

107

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1 August 2017

issue

47

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1 August 2017

page(s)

20459-20464

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Dectin-2 is a Syk-coupled pattern recognition receptor crucial for Th17 responses to fungal infection

1 August 2017

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IL-1 family members and STAT activators induce cytokine production by Th2, Th17, and Th1 cells

6 July 2018

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6 July 2018

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Omega-1, a glycoprotein secreted by Schistosoma mansoni eggs, drives Th2 responses

6 July 2018

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The major component in schistosome eggs responsible for conditioning dendritic cells for Th2 polarization is a T2 ribonuclease (omega-1)

6 July 2018

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6 July 2018

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The NALP3 inflammasome is involved in the innate immune response to amyloid-beta

6 July 2018

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Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants

6 July 2018

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Dendritic cell interaction with Candida albicans critically depends on N-linked mannan.

6 July 2018

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Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica

6 July 2018

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Dectin-2 is a pattern recognition receptor for fungi that couples with the Fc receptor gamma chain to induce innate immune responses

6 July 2018

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6 July 2018

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R406, an orally available spleen tyrosine kinase inhibitor blocks fc receptor signaling and reduces immune complex-mediated inflammation

6 July 2018

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Gout-associated uric acid crystals activate the NALP3 inflammasome

6 July 2018

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Schistosome larvae stimulate macrophage cytokine production through TLR4-dependent and -independent pathways.

6 July 2018

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6 July 2018

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6 July 2018

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The pyrin domain: a possible member of the death domain-fold family implicated in apoptosis and inflammation

6 July 2018

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Mice deficient in IL-1beta manifest impaired contact hypersensitivity to trinitrochlorobenzone.

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Downregulation of Th1 cytokine production accompanies induction of Th2 responses by a parasitic helminth, Schistosoma mansoni

6 July 2018

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A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes

6 July 2018

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Tumour necrosis factor alpha restores granulomas and induces parasite egg-laying in schistosome-infected SCID mice

6 July 2018

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Lack of antigen-specific Th1 response alters granuloma formation and composition in Schistosoma mansoni-infected MyD88-/- mice.

6 July 2018

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Schistosoma mansoni soluble egg antigens are internalized by human dendritic cells through multiple C-type lectins and suppress TLR-induced dendritic cell activation

21 January 2018

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Helminth antigens modulate immune responses in cells from multiple sclerosis patients through TLR2-dependent mechanisms

21 January 2018

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Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence

21 January 2018

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Dectin-1 stimulation by Candida albicans yeast or zymosan triggers NFAT activation in macrophages and dendritic cells

21 January 2018

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Transforming growth factor-beta and Th17 responses in resistance to primary murine schistosomiasis mansoni.

21 January 2018

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TNF is essential for the cell-mediated protective immunity induced by the radiation-attenuated schistosome vaccine.

21 January 2018

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An IL-12-based vaccination method for preventing fibrosis induced by schistosome infection

27 October 2018

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Cytokine Regulation of Periportal Fibrosis in Humans Infected with Schistosoma mansoni: IFN- Is Associated with Protection Against Fibrosis and TNF- with Aggravation of Disease

21 January 2018

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12 December 2020

Endogenous IL-1 receptor antagonist protein (IRAP) regulates schistosome egg granuloma formation and the regional lymphoid response

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12 December 2020

IL-1 receptor antagonist (IL-1ra) expression, function, and cytokine-mediated regulation during mycobacterial and schistosomal antigen-elicited granuloma formation

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Helminth antigens modulate TLR-initiated dendritic cell activation

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Identifiers

DOI

10.1073/PNAS.1010337107

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1 August 2017

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1 August 2017

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