Inflammatory caspases and inflammasomes: master switches of inflammation (Q28263855)

Cell Death & Differentiation

Europe PubMed Central

title

Inflammatory caspases and inflammasomes: master switches of inflammation (English)

0 references

0 references

1 reference

2

J Tschopp

0 references

author name string

F Martinon

series ordinal

1

0 references

language of work or name

English

0 references

publication date

January 2007

0 references

published in

0 references

volume

14

0 references

page(s)

10-22

0 references

issue

1

0 references

cites work

Identification of a monocyte specific pre-interleukin 1 beta convertase activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Molecular cloning of the interleukin-1 beta converting enzyme

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Initial sequence of the chimpanzee genome and comparison with the human genome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Gene losses during human origins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Spread of an inactive form of caspase-12 in humans is due to recent positive selection

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Activation of interferon-gamma inducing factor mediated by interleukin-1beta converting enzyme

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Caspase-1 processes IFN-gamma-inducing factor and regulates LPS-induced IFN-gamma production.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Interleukin-18 and host defense against infection

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Tumor necrosis factor (cachectin) is an endogenous pyrogen and induces production of interleukin 1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Humoral links between sleep and the immune system: research issues

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Interleukin-1beta-mediated induction of Cox-2 in the CNS contributes to inflammatory pain hypersensitivity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Cytokines in atherosclerosis: pathogenic and regulatory pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Inflammation in atherosclerosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

IL-1 is required for tumor invasiveness and angiogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Infiltration of COX-2-expressing macrophages is a prerequisite for IL-1 beta-induced neovascularization and tumor growth.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Chondroprotective drugs in degenerative joint diseases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Aspects of the involvement of interleukin-1 and nitric oxide in the pathogenesis of insulin-dependent diabetes mellitus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Glucose-induced beta cell production of IL-1beta contributes to glucotoxicity in human pancreatic islets

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

The role of inflammation in CNS injury and disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Murine caspase-11, an ICE-interacting protease, is essential for the activation of ICE.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Expression analysis of the human caspase-1 subfamily reveals specific regulation of the CASP5 gene by lipopolysaccharide and interferon-gamma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

The endoplasmic reticulum is a key component of the plasma cell death pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Abeta-induced cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Caspase-12 and caspase-4 are not required for caspase-dependent endoplasmic reticulum stress-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Caspase-12 and endoplasmic reticulum stress mediate neurotoxicity of pathological prion protein.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Regulation of the expression and processing of caspase-12

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Endoplasmic Reticulum Stress Induces Apoptosis by an Apoptosome-dependent but Caspase 12-independent Mechanism

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Enhanced bacterial clearance and sepsis resistance in caspase-12-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Differential modulation of endotoxin responsiveness by human caspase-12 polymorphisms

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Human ICE/CED-3 protease nomenclature

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Mechanisms of apoptosis through structural biology

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

The PIDDosome, a protein complex implicated in activation of caspase-2 in response to genotoxic stress

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Cytochrome C-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

The CD95(APO-1/Fas) DISC and beyond

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

The apoptosome activates caspase-9 by dimerization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

A unified model for apical caspase activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

TIR, CARD and PYRIN: three domains for an antimicrobial triad

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

NLRs join TLRs as innate sensors of pathogens

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

NOD-LRR proteins: role in host-microbial interactions and inflammatory disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Identification of Ipaf, a human caspase-1-activating protein related to Apaf-1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

NALPs: a novel protein family involved in inflammation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

The gene for neuronal apoptosis inhibitory protein is partially deleted in individuals with spinal muscular atrophy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Cleavage of human inhibitor of apoptosis protein XIAP results in fragments with distinct specificities for caspases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Genomic sequence analysis of the mouse Naip gene array

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

The Birc1e cytosolic pattern-recognition receptor contributes to the detection and control of Legionella pneumophila infection

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

ASC is essential for LPS-induced activation of procaspase-1 independently of TLR-associated signal adaptor molecules

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

The PYRIN-CARD protein ASC is an activating adaptor for caspase-1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

The leucine-rich repeat as a protein recognition motif

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Association of mutations in the NALP3/CIAS1/PYPAF1 gene with a broad phenotype including recurrent fever, cold sensitivity, sensorineural deafness, and AA amyloidosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Cutting edge: CIAS1/cryopyrin/PYPAF1/NALP3/CATERPILLER 1.1 is an inducible inflammatory mediator with NF-kappa B suppressive properties

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Evolution of Ribonuclease Inhibitor by Exon Duplication

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Ribonuclease inhibitor: structure and function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Host-microbe interactions: shaping the evolution of the plant immune response

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Resistance gene signaling in plants--complex similarities to animal innate immunity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Interleukin 1 is processed and released during apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

The P2X7 receptor: a key player in IL-1 processing and release

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Kinetics and mechanism of ATP-dependent IL-1 beta release from microglial cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

ATP acts as an agonist to promote stimulus-induced secretion of IL-1 beta and IL-18 in human blood

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Absence of the P2X7 receptor alters leukocyte function and attenuates an inflammatory response

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Altered cytokine production in mice lacking P2X(7) receptors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Mechanisms of caspase-1 activation by P2X7 receptor-mediated K+ release.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Cryopyrin activates the inflammasome in response to toxins and ATP

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Gout-associated uric acid crystals activate the NALP3 inflammasome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Distinct roles of TLR2 and the adaptor ASC in IL-1beta/IL-18 secretion in response to Listeria monocytogenes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

New mutations of CIAS1 that are responsible for Muckle-Wells syndrome and familial cold urticaria: a novel mutation underlies both syndromes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Interleukin-1-receptor antagonist in the Muckle-Wells syndrome.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Prevention of cold-associated acute inflammation in familial cold autoinflammatory syndrome by interleukin-1 receptor antagonist

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Plasma interleukin (IL)-18 (interferon-gamma-inducing factor) and other inflammatory cytokines in patients with gouty arthritis and monosodium urate monohydrate crystal-induced secretion of IL-18.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Functional caspase-1 is required for Langerhans cell migration and optimal contact sensitization in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Mice deficient in IL-1beta manifest impaired contact hypersensitivity to trinitrochlorobenzone.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Release of IL-1beta via IL-1beta-converting enzyme in a skin dendritic cell line exposed to 2,4-dinitrofluorobenzene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Salmonella rapidly kill dendritic cells via a caspase-1-dependent mechanism

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Caspase-1 activation by Salmonella

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Innate immunity against Francisella tularensis is dependent on the ASC/caspase-1 axis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Internalization and phagosome escape required for Francisella to induce human monocyte IL-1beta processing and release

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Anthrax lethal toxin rapidly activates caspase-1/ICE and induces extracellular release of interleukin (IL)-1beta and IL-18.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophages

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1beta via Ipaf

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Cytosolic recognition of flagellin by mouse macrophages restricts Legionella pneumophila infection

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Flagellin-deficient Legionella mutants evade caspase-1- and Naip5-mediated macrophage immunity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Naip5/Birc1e and susceptibility to Legionella pneumophila

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Mater, a maternal effect gene required for early embryonic development in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

A human homologue of mouse Mater, a maternal effect gene essential for early embryonic development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

In silico identification and structural features of six new genes similar to MATER specifically expressed in the oocyte.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Bovine mater-like NALP9 is an oocyte marker gene.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Bovine NALP5, NALP8, and NALP9 genes: assignment to a QTL region and the expression in adult tissues, oocytes, and preimplantation embryos

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Age-associated alteration of gene expression patterns in mouse oocytes.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

The mouse germ-cell-specific leucine-rich repeat protein NALP14: a member of the NACHT nucleoside triphosphatase family.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Interacting quantitative trait loci control loss of peripheral tolerance and susceptibility to autoimmune ovarian dysgenesis after day 3 thymectomy in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Mutations in NALP7 cause recurrent hydatidiform moles and reproductive wastage in humans

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

The interleukin-1 system and female reproduction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Promoter mutations of an essential gene for pollen development result in disease resistance in rice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

An evolutionarily conserved mediator of plant disease resistance gene function is required for normal Arabidopsis development.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

ICEBERG: a novel inhibitor of interleukin-1beta generation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Cop, a caspase recruitment domain-containing protein and inhibitor of caspase-1 activation processing

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Regulation of IL-1beta generation by Pseudo-ICE and ICEBERG, two dominant negative caspase recruitment domain proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

INCA, a novel human caspase recruitment domain protein that inhibits interleukin-1beta generation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

The PAAD/PYRIN-only protein POP1/ASC2 is a modulator of ASC-mediated nuclear-factor-kappa B and pro-caspase-1 regulation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

A poxvirus-encoded pyrin domain protein interacts with ASC-1 to inhibit host inflammatory and apoptotic responses to infection.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Poxviruses aren't stuPYD.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Familial Mediterranean fever: the genetics of inflammation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Targeted disruption of pyrin, the FMF protein, causes heightened sensitivity to endotoxin and a defect in macrophage apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

The tripartite motif family identifies cell compartments

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

CATERPILLERs, pyrin and hereditary immunological disorders

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

The estrogen-responsive B box protein: a novel enhancer of interleukin-1beta secretion

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Structure of the PRYSPRY-domain: implications for autoinflammatory diseases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Cryopyrin and pyrin activate caspase-1, but not NF-kappaB, via ASC oligomerization.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Higher than expected carrier rates for familial Mediterranean fever in various Jewish ethnic groups

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Mutation and haplotype studies of familial Mediterranean fever reveal new ancestral relationships and evidence for a high carrier frequency with reduced penetrance in the Ashkenazi Jewish population.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Episodic evolution of pyrin in primates: human mutations recapitulate ancestral amino acid states

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Pyrin binds the PSTPIP1/CD2BP1 protein, defining familial Mediterranean fever and PAPA syndrome as disorders in the same pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021

Mutation of mouse Mayp/Pstpip2 causes a macrophage autoinflammatory disease.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402038

7 January 2021