Adipokines: molecular links between obesity and atheroslcerosis (Q34384883)

1 August 2017

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title

Adipokines: molecular links between obesity and atheroslcerosis (English)

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1 August 2017

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David C W Lau

1

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1 August 2017

Bikramjit Dhillon

2

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1 August 2017

Hongyun Yan

3

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1 August 2017

Paul E Szmitko

4

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1 August 2017

Subodh Verma

5

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1 August 2017

14 January 2005

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American Journal of Physiology Heart and Circulatory Physiology

1 August 2017

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1 August 2017

288

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1 August 2017

H2031-41

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1 August 2017

5

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Adipose tissue as an endocrine organ

1 August 2017

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https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Leptin, the product of Ob gene, promotes angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Shattuck lecture--cardiovascular medicine at the turn of the millennium: triumphs, concerns, and opportunities.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Association between measures of insulin sensitivity and circulating levels of interleukin-8, interleukin-6 and tumor necrosis factor-alpha. Effect of weight loss in obese men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Acute intravenous leptin infusion increases glucose turnover but not skeletal muscle glucose uptake in ob/ob mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Resistin promotes smooth muscle cell proliferation through activation of extracellular signal-regulated kinase 1/2 and phosphatidylinositol 3-kinase pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Angiotensinogen and its cleaved derivatives inhibit angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

A prospective study of obesity and risk of coronary heart disease among diabetic women

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure<SUBTITLE>The JNC 7 Report</SUBTITLE>

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Endothelial cell apoptosis: biochemical characteristics and potential implications for atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Monocyte chemoattractant protein-1 is produced in isolated adipocytes, associated with adiposity and reduced after weight loss in morbid obese subjects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

C-reactive protein increases plasminogen activator inhibitor-1 expression and activity in human aortic endothelial cells: implications for the metabolic syndrome and atherothrombosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Bradykinin enhances sympathetic neurotransmission in rat blood vessels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Effect of weight loss and lifestyle changes on vascular inflammatory markers in obese women: a randomized trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III)

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Inflammation, insulin resistance, and obesity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Elevated levels of acute-phase proteins and plasminogen activator inhibitor-1 predict the development of type 2 diabetes: the insulin resistance atherosclerosis study

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

C-reactive protein and body mass index in children: findings from the Third National Health and Nutrition Examination Survey, 1988-1994.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Prevalence of the metabolic syndrome among US adults: findings from the third National Health and Nutrition Examination Survey

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

C-reactive protein is an independent predictor of risk for the development of diabetes in the West of Scotland Coronary Prevention Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Leptin induces endothelial cell migration through Akt, which is inhibited by PPARgamma-ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Cardiovascular risk factors in confirmed prediabetic individuals. Does the clock for coronary heart disease start ticking before the onset of clinical diabetes?

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Energy restriction and weight loss on very-low-fat diets reduce C-reactive protein concentrations in obese, healthy women

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Correlations of adiponectin level with insulin resistance and atherosclerosis in Japanese male populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Mechanisms of TNF-alpha-induced insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Mechanism by which high-dose aspirin improves glucose metabolism in type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Serum amyloid A as a predictor of coronary artery disease and cardiovascular outcome in women: the National Heart, Lung, and Blood Institute-Sponsored Women's Ischemia Syndrome Evaluation (WISE).

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Obesity and insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Reduction in the Incidence of Type 2 Diabetes with Lifestyle Intervention or Metformin

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Plasminogen-activator inhibitor type 1 and coronary artery disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Leptin-dependent platelet aggregation and arterial thrombosis suggests a mechanism for atherothrombotic disease in obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Obesity as a medical problem

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Impact of Weight Loss on Inflammatory Proteins and Their Association With the Insulin Resistance Syndrome in Morbidly Obese Patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Disruption of adiponectin causes insulin resistance and neointimal formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Insulin resistance and adiposity correlate with acute-phase reaction and soluble cell adhesion molecules in type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Elevated C-reactive protein: another component of the atherothrombotic profile of abdominal obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Disordered fat storage and mobilization in the pathogenesis of insulin resistance and type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Adipocyte differentiation factor (ADF): a protein secreted by mature fat cells that induces preadipocyte differentiation in culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Inflammation and atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Hyperglycemia-induced production of acute phase reactants in adipose tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

The adipocyte and hemostatic balance in obesity: studies of PAI-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

PPARgamma ligands increase expression and plasma concentrations of adiponectin, an adipose-derived protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Acute hyperglycemia induces an oxidative stress in healthy subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Insulin action in the vasculature: physiology and pathophysiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Obesity accelerates the progression of coronary atherosclerosis in young men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Differentiation between obesity and insulin resistance in the association with C-reactive protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Prevalence of obesity, diabetes, and obesity-related health risk factors, 2001

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Interleukin-6 stimulates hepatic triglyceride secretion in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Glucose-dependent regulation of cholesterol ester metabolism in macrophages by insulin and leptin

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Adipocyte-derived plasma protein, adiponectin, suppresses lipid accumulation and class A scavenger receptor expression in human monocyte-derived macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Adiponectin, an adipocyte-derived plasma protein, inhibits endothelial NF-kappaB signaling through a cAMP-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Novel modulator for endothelial adhesion molecules: adipocyte-derived plasma protein adiponectin

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Reciprocal association of C-reactive protein with adiponectin in blood stream and adipose tissue.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Potential role of leptin in angiogenesis: leptin induces endothelial cell proliferation and expression of matrix metalloproteinases in vivo and in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

C-reactive protein: a critical update

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

C-reactive protein, interleukin 6, and risk of developing type 2 diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Leptin induces endothelin-1 in endothelial cells in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Banting lecture 1988. Role of insulin resistance in human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Clinical application of C-reactive protein for cardiovascular disease detection and prevention

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

C-reactive protein, the metabolic syndrome, and risk of incident cardiovascular events: an 8-year follow-up of 14 719 initially healthy American women

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Body size and fat distribution as predictors of coronary heart disease among middle-aged and older US men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Atherosclerosis — An Inflammatory Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Raised interleukin-6 levels in obese patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Suppressor of cytokine signaling-3 (SOCS-3), a potential mediator of interleukin-6-dependent insulin resistance in hepatocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Arachidonic acid metabolites of the lipoxygenase as well as the cyclooxygenase pathway may be involved in regulating preadipocyte differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Leptin reverses insulin resistance and diabetes mellitus in mice with congenital lipodystrophy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Biological action of leptin as an angiogenic factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

BRL 49653 blocks the lipolytic actions of tumor necrosis factor-alpha: a potential new insulin-sensitizing mechanism for thiazolidinediones

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Adipogenesis and obesity: rounding out the big picture

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Elevated circulating free fatty acid levels impair endothelium-dependent vasodilation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

The hormone resistin links obesity to diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Weight loss reduces C-reactive protein levels in obese postmenopausal women

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Angiotensin II is associated with activation of NF-kappaB-mediated genes and downregulation of PPARs

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Lipotoxicity in the pathogenesis of obesity-dependent NIDDM. Genetic and clinical implications.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Protection from obesity-induced insulin resistance in mice lacking TNF-alpha function

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Fundamentals of endothelial function for the clinical cardiologist

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Endothelin antagonism and interleukin-6 inhibition attenuate the proatherogenic effects of C-reactive protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Resistin promotes endothelial cell activation: further evidence of adipokine-endothelial interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

A self-fulfilling prophecy: C-reactive protein attenuates nitric oxide production and inhibits angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Hyperglycemia potentiates the proatherogenic effects of C-reactive protein: reversal with rosiglitazone.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Subcutaneous and visceral adipose tissue: their relation to the metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Interleukin-6-deficient mice develop mature-onset obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

C-reactive protein upregulates angiotensin type 1 receptors in vascular smooth muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Weight, weight change, and coronary heart disease in women. Risk within the 'normal' weight range.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Correlation of the adipocyte-derived protein adiponectin with insulin resistance index and serum high-density lipoprotein-cholesterol, independent of body mass index, in the Japanese population

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Nitric oxide promotes differentiation of rat white preadipocytes in culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

The effect of thiazolidinediones on plasma adiponectin levels in normal, obese, and type 2 diabetic subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of Ikkbeta

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

C-reactive protein in healthy subjects: associations with obesity, insulin resistance, and endothelial dysfunction: a potential role for cytokines originating from adipose tissue?

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Elevated C-reactive protein levels in overweight and obese adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

Obesity in the new millennium

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01058.2004

10.1152/AJPHEART.01058.2004

21 January 2018

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DOI

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1 August 2017

1 reference