RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis (Q34387272)

1 August 2017

title

RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis (English)

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1 August 2017

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Manolis Pasparakis

16

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Apostolos Polykratis

object named as

Apostolos Polykratis

4

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Laurens Wachsmuth

6

object named as

Laurens Wachsmuth

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1 August 2017

Marius Dannappel

1

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1 August 2017

Katerina Vlantis

2

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1 August 2017

Snehlata Kumari

3

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1 August 2017

Chun Kim

5

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1 August 2017

Christina Eftychi

7

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1 August 2017

Juan Lin

8

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1 August 2017

Teresa Corona

9

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1 August 2017

Nicole Hermance

10

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1 August 2017

Matija Zelic

11

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1 August 2017

Petra Kirsch

12

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1 August 2017

Marijana Basic

13

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1 August 2017

Andre Bleich

14

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1 August 2017

Michelle Kelliher

15

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1 August 2017

language of work or name

English

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publication date

17 August 2014

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1 August 2017

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1 August 2017

volume

513

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1 August 2017

issue

7516

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1 August 2017

page(s)

90-94

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Cutting edge: RIPK1 Kinase inactive mice are viable and protected from TNF-induced necroptosis in vivo

1 August 2017

cites work

1 reference

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6 July 2018

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Regulated necrosis: the expanding network of non-apoptotic cell death pathways.

6 July 2018

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Tumor necrosis factor receptor signaling in keratinocytes triggers interleukin-24-dependent psoriasis-like skin inflammation in mice

6 July 2018

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Paneth cells as a site of origin for intestinal inflammation.

6 July 2018

1 reference

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Control of life-or-death decisions by RIP1 kinase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206266

Survival function of the FADD-CASPASE-8-cFLIP(L) complex

6 July 2018

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Constitutive IKK2 activation in intestinal epithelial cells induces intestinal tumors in mice

6 July 2018

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RIG-I RNA helicase activation of IRF3 transcription factor is negatively regulated by caspase-8-mediated cleavage of the RIP1 protein

6 July 2018

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Tumor necrosis factor receptor-associated factor (TRAF) 2 controls homeostasis of the colon to prevent spontaneous development of murine inflammatory bowel disease

6 July 2018

1 reference

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Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206266

RIP3 mediates the embryonic lethality of caspase-8-deficient mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206266

Functional complementation between FADD and RIP1 in embryos and lymphocytes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206266

In TNF-stimulated cells, RIPK1 promotes cell survival by stabilizing TRAF2 and cIAP1, which limits induction of non-canonical NF-kappaB and activation of caspase-8

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206266

TNFα induced noncanonical NF-κB activation is attenuated by RIP1 through stabilization of TRAF2.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206266

Virus inhibition of RIP3-dependent necrosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206266

Intestinal bacteria and the regulation of immune cell homeostasis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206266

Inflammatory bowel disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206266

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206266

Loss of epithelial RelA results in deregulated intestinal proliferative/apoptotic homeostasis and susceptibility to inflammation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206266

Probiotic Escherichia coli Nissle 1917 inhibits leaky gut by enhancing mucosal integrity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206266

IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206266

IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206266

Impaired epidermal wound healing in vivo upon inhibition or deletion of Rac1.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206266

IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206266

IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206266

RIP1 is an essential mediator of Toll-like receptor 3-induced NF-kappa B activation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206266

Kinase RIP3 is dispensable for normal NF-kappa Bs, signaling by the B-cell and T-cell receptors, tumor necrosis factor receptor 1, and Toll-like receptors 2 and 4.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206266

High-efficiency deleter mice show that FLPe is an alternative to Cre-loxP

6 July 2018

1 reference

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Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function

6 July 2018

1 reference

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The death domain kinase RIP mediates the TNF-induced NF-kappaB signal

6 July 2018

1 reference

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A cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cells

6 July 2018

1 reference

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Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4206266

FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation.

6 July 2018

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RIP kinase-dependent necrosis drives lethal systemic inflammatory response syndrome

21 January 2018

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https://api.crossref.org/works/10.1038%2FNATURE13608

Rip1 mediates the Trif-dependent toll-like receptor 3- and 4-induced NF-{kappa}B activation but does not contribute to interferon regulatory factor 3 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13608

The kinase activity of Rip1 is not required for tumor necrosis factor-alpha-induced IkappaB kinase or p38 MAP kinase activation or for the ubiquitination of Rip1 by Traf2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13608

Canonical NF-κB Activity, Dispensable for B Cell Development, Replaces BAFF-Receptor Signals and Promotes B Cell Proliferation upon Activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13608

Oligodendrocyte-specific FADD deletion protects mice from autoimmune-mediated demyelination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13608

Cis elements of the villin gene control expression in restricted domains of the vertical (crypt) and horizontal (duodenum, cecum) axes of the intestine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13608

Tissue-specific and inducible Cre-mediated recombination in the gut epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13608

Keratin 14 Cre transgenic mice authenticate keratin 14 as an oocyte-expressed protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13608

NEMO/IKK gamma-deficient mice model incontinentia pigmenti.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13608

A T-bet gradient controls the fate and function of CCR6-RORγt+ innate lymphoid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13608

Epithelial NEMO links innate immunity to chronic intestinal inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13608

Slide preparation for single-cell-resolution imaging of fluorescent proteins in their three-dimensional near-native environment

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25132550

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The Adaptor Protein FADD Protects Epidermal Keratinocytes from Necroptosis In Vivo and Prevents Skin Inflammation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25132550

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NATURE13608

1 reference

Dimensions Publication ID

1 August 2017

1032702328

0 references

Fatcat ID

release_dntww2vnknh3hmdiskzbv7nixy

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/dntww2vnknh3hmdiskzbv7nixy

mapped directly with Wikidata item

24 November 2022

based on heuristic

PMC publication ID

4206266

1 reference

1 August 2017

1 reference